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Hepatology Clinical Care

Faculty physicians in the Division of Gastroenterology and Hepatology who specialize in hepatology are renowned nationally as leading authorities in the field and are engaged in the comprehensive care of patients with liver disease. Our hepatology team ranks among the nation's largest general hepatology groups, boasting a roster of 18 MDs and Advanced Practice Providers (APPs) together providing specialized hepatology care. Raj Vuppalanchi, MD currently serves as the director of hepatology while Marco Lacerda, MD serves as the medical director for the Liver Transplant program. As the only academic hepatology group in Indiana, we endeavor to enhance health care delivery using comprehensive and innovative strategies within both traditional inpatient and outpatient settings.

Focus Areas

As the sole academic hepatology group in Indiana, our physicians and APPs strive to optimize the care of patients with chronic liver disease through the implementation of novel healthcare delivery models. Our faculty lead several clinics dedicated to specific liver diseases that are based on the diverse clinical and research interests of the division.

Looking for patient care?

To schedule an appointment with an IU School of Medicine faculty hepatologist or hepatology physician assistant, contact Indiana University Health at (317) 944-0980 or access the Find a Provider portal.

Expert care of those with acute or chronic hepatitis B and chronic hepatitis C with or without cirrhosis with support from our IU Specialty Pharmacy. Open access referrals from IU emergency departments for linkage to care and treatment.

Metabolic dysfunction-Associated Steatotic Liver Disease

Aligning patient oriented clinical research with comprehensive care led by Niharika Samala, MD with an emphasis on addressing multidisciplinary risk factors associated with the development of MASLD/MASH including genetic, environmental, dietary, lifestyle, and comorbid conditions in coordinated care with dieticians, endocrinologists, cardiologists, medical weight loss specialists, and primary care providers.

Specialized care for women who are pregnant and have concomitant liver disease such as elevated liver tests, cholestasis, cirrhosis, and hepatic adenomas.

Pairing clinical research and innovative clinical care with an emphasis on novel therapies/therapeutics for rare liver diseases.

Pairing patient-oriented clinical research along with the most up-to-date care standards led by Archita Desai, MD, with an emphasis on measuring quality of life and patient reported outcomes.

Led by John Holden, MD, the multidisciplinary liver tumor board brings specialists in transplant and hepatobiliary surgery, transplant hepatology, medical and radiation oncology, and Interventional Radiology together weekly to review new and recurrent cases of primary liver cancer enabling personalized care recommendations and access to highly specialized cancer treatments and clinical trials with the support of our dedicated hepatology nurse navigator, Mary Kiefer, RN, and coordinated by Michelle Haugh, PA-C.

Dedicated weekly clinic for the evaluation and treatment of those with hepatocellular carcinoma (HCC), cholangiocarcinoma, or undiagnosed liver nodules led by our director of Liver Oncology and the PA who collaborates with him as well as coordinates our weekly tumor board.

Dedicated weekly appointments allowing access within a few days (Transfer Avoidance) or less than 2 weeks (Hep Urgent) to an expertly trained hepatology PA or hepatologist to patients with new onset or severe symptoms of liver disease, or high-acuity liver conditions that cannot wait (current or new patients) with the intention of preventing ER visits, readmissions, and hospital transfers.

Allows patients to remain at their local hospital within the IU Health system and receive expert hepatology care from dedicated hepatology PAs with the support of hepatologists virtually, delivering sub-specialty expertise to rural communities and minimizing transfers downtown to our Academic Health Center. Currently, inpatient coverage with telemedicine consultation services is offered at IU Health West, IU Health Bloomington and IU Health Saxony with expansion to other IU Health facilities planned.

Enables patients to shorten an inpatient hospital admission stay and recover at home with family support while still receiving specialized medical care by APPs and RNs with support of the hepatology team.

3 clinics every week at both our downtown and northside DaLD clinic locations dedicated to continuing care for patients with decompensated liver disease during their transition from an inpatient hospital admission to their outpatient destination after discharge to prevent readmissions. All patients are seen by a hepatology PA within 14 days of discharge either in-person or virtually.

Home to the only liver transplant (LT) program in the state, we completed 189 successful liver transplants in 2023 and include a living-donor program. Led by director, Marco Lacerda, MD, along with Marwan Ghabril, MD who serves as the director of Inpatient Hepatology at the AHC, our transplant hepatologists receive internal referrals from all over the state of Indiana and bordering states as well, including our own general hepatology LT referrals. Lauren Nephew, MD is nationally recognized for her research focused on health disparities in liver disease and equitable access to liver transplantation.

Clinical Liver Research

The Division of Gastroenterology and Hepatology is a leading liver research institute in the country, conducting over 100 active studies, including NIH-funded and investigator-initiated trials. Our significant advancements in Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Steatotic Liver Disease research, along with our expertise in drug safety, position our investigators as key opinion leaders. We are at the forefront of developing new treatments for liver conditions such as Primary Biliary Cholangitis (PBC), Primary Sclerosing Cholangitis (PSC), cirrhosis, Autoimmune Hepatitis (AIH), and alcohol-associated liver disease (ALD), contributing greatly to the field while improving patient care for Hoosiers and others affected by liver disease.

Learn more about clinical liver research

Urgent questions or concerns regarding outpatient referrals?

Please contact Mary Kiefer, RN, BSN, the clinical nurse navigator with hepatology.