Gastroparesis Research Studies

Gastroparesis, or paralysis of the stomach, refers to a stomach that empties slowly. Gastroparesis is characterized by symptoms by bloating, nausea, vomiting and feeling full after eating only a small amount of food. Some patients can be quite sick with nausea, retching, vomiting and weight loss requiring ER visits and hospitalizations. Gastroparesis can occur as a result of several conditions, especially in people with diabetes. However, the cause of gastroparesis is not known in many patients. It is more common in women than men.

Enrolling: Yes

Principle Investigator: John M. Wo, MD

Primary Outcomes Measured: Compare 3D--dimensional gastric peristalsis progression before & after test meals in healthy volunteers and patients with gastroparesis

Secondary Outcomes Measured:

1. Compare colored 3-D heat map of stomach contraction frequency before & after test meals in healthy volunteers and patients with gastroparesis
2. Compare pylorus mean opening diameter before & after test meals in healthy volunteers and patients with gastroparesis 

Interested in this study? Please contact the coordinator below:

Kara Murphy
clarkara@iu.edu

Anita Gupta
anigupta@iu.edu

Enrolling: Yes

Principle Investigator: Thomas V. Nowak, MD

Duration: TBD

Primary Outcomes Measured: To measure the amplitude of vagal nerve compound action potentials in gastroparetic subjects with symptoms of nausea and vomiting with skin electrodes over right and left vagus nerve during ABVN stimulation and also during the vagal maneuvers phase.

Secondary Outcomes Measured: To measure changes in the amplitude of the surface electrogastrogram during ABVN and also during the vagal maneuvers phase.

Interested in this study? Please contact the coordinator below

Anita Gupta

(317) 278-0406
anitgupta@iu.edu