Physician-scientists at IU School of Medicine conduct ground-breaking research studies to understand eosinophilic GI disorders.

Eosinophilic GI Disorders Research Studies

Eosinophilic esophagitis (EoE) is a chronic, allergic inflammatory disease of the esophagus. EoE affects children and adults. It occurs when a type of white blood cell, the eosinophil, accumulates in the esophagus. The elevated number of eosinophils causes injury and inflammation to the esophagus. Eventually leading to scar tissues. Adults with EoE usually present with difficulty swallowing. Many patient have other allergic diseases, such as seasonal allergies, asthma, allergic reactions to foods and environment.

Investigators

William R. Kessler, MD

Associate Professor of Clinical Medicine

Read Bio William R. Kessler, MD

John M. Wo, MD

Douglas Rex Professor of Gastroenterology and Hepatology

Read Bio John M. Wo, MD

Akira Saito, MD

Assistant Professor of Clinical Medicine

Read Bio Akira Saito, MD

Robert M. Siwiec, MS, MD

Associate Professor of Clinical Medicine

Read Bio Robert M. Siwiec, MS, MD

Open Research Studies for Eosinophilic Eosophagitis

Changes in Esophageal Distensibility in Patients with Esophageal Eosinophilia with Proton Pump Inhibitors in Patients with Eosinophilic Esophagitis: A Pilot Study

Enrolling: Yes
Principle Investigator: Akita Saito, MD
Duration: 4 months
Primary Outcomes Measured: To measure the changes in esophageal distensibility before and after treatment with PPI, topical steroids, or elimination diet in patients with esophageal eosinophilia.

Secondary Outcomes Measured: To correlate the changes in esophageal distensibility with dysphagia before and after treatment with PPI, topical steroids, or elimination diet in patients with esophageal eosinophilia.

Interested in this study? Please contact the coordinator below:
Kara Murphy
clarkara@iu.edu
(317) 278-0612

View the study on clinicaltrials.gov