Investigators
Open Research Studies for Other Motility Research
Indiana University GI Neuromuscular Pathology Prospective Registry
Enrolling: Yes
Principle Investigator: John M. Wo, MD
Duration: 2 years
Primary Outcomes Measured:
- Follow up clinical data will be obtained before, 6 months, 1.5 years, and 2 years after the full thickness biopsy
- Follow up data PAGI_SYM Overall Treatment Effect by Patient Overall Treatment Effect by Physician
Secondary Outcomes Measured:
- Responders will be defined as >50% improvement of the GCSI total score at 6 month after surgical GES.
- Patients with gastroparesis from type 1 DM versus patients with idiopathic gastroparesis.
- Patients with gastroparesis from type 1 DM versus gastroparesis from type 2 DM.
- Neuromuscular pathology results of the gastric body and proximal jejunum will be correlated with the following: Symptom severity (GCSI total score), predominant symptom presentation, severity of delayed gastric emptying.
Interested in this study? Please contact the coordinator below:
Kara Murphy
clarkara@iu.edu
Anita Gupta
anigupta@iu.edu
GI Motility Diagnosis Registry
Enrolling: Yes
Principle Investigator: John M. Wo, MD
Duration: TBD
Primary Outcomes Measured: Identification of patients by accurate motility diagnosis.
Secondary Outcomes Measured:
- To develop Patient Reported Outcome (PRO) measurements in patients with small intestinal bacterial overgrowth (SIBO)
- To develop Patient Reported Outcome (PRO) measurements in patients with gastroparesis
Kara Murphy
clarkara@iu.edu
(317) 278-0612
Clinical Outcomes Assessment (COA) for Chronic Intestinal Pseudo-Obstruction (CIPO)
Enrolling: Yes
Principle Investigator: Akira Saito, MD
Duration: Recruiting 50 patients based in the US.
Primary Outcomes Measured:
- Develop a de novo CIPO-specific PRO that is able to capture change in core CIPO visible signs and symptoms across all etiologies and severity levels.
- Develop a de novo CIPO-specific PRO that is fit-for-purpose for use as a primary endpoint in a clinical trial setting.
Interested in this study? Please contact the coordinator below:
Kara Murphy
clarkara@iu.edu
(317) 278-0612