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Physician-scientists at IU School of Medicine conduct ground-breaking research studies to understand recurrent C. difficile.

Recurrent C. difficile Research Studies

Clostridium difficile, also known as Clostridioides difficile and often referred to as C. difficile or C. diff, is a bacterium that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon.

Investigators

4964-Fischer, Monika

Monika Fischer, MD

Professor of Medicine

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Open Research Studies for Recurrent C. difficile

IMT Database (U. Minnesota)

Enrolling: Yes

Principle Investigator: Monika Fischer, MD

Duration: 1 year

Patient Population:  Adult patients receiving  treatment for recurrent CDI

Study Intervention:  Oral IMT or colonic IMT – questionnaire follow up for 1 year.

Interested in this study? Please contact the IBD research team: iuibd@iu.edu

Vedanta RestoratiVE303

Enrolling: Yes
Principle Investigator: Monika Fischer, MD
Duration: 24 weeks, 17 visits
Patient Population: Adult patients with recurrent C.Diff Infections.
Interested in this study? Please contact the IBD research team: iuibd@iu.edu

Closed Recurrent C difficile Research Studies

Duration: 26 weeks

Patient Population:  Adult patients with IBD and CDI undergoing an FMT as standard of care

Study Intervention:  Bezlotuxumab Infusion in conjunction with FMT

Possibility of Placebo:  50% of not receiving Bezlotuxumab