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Ulcerative Colitis Research Studies

Ulcerative colitis (UC) is an inflammatory bowel disease. It causes irritation, inflammation, and ulcers in the lining of the large intestine.


5139-Bohm, Matthew

Matthew Bohm, BA, DO

Assistant Professor of Clinical Medicine

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4964-Fischer, Monika

Monika Fischer, MD

Associate Professor of Medicine

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5125-Sagi, Sashi

Sashi Sagi, MBBS

Assistant Professor of Clinical Medicine

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Open Research Studies for Ulcerative Colitis

Seres Eco-Reset

Enrolling: Yes

Principle Investigator: Monika Fischer, MD

Duration: 17 Months (Approx. 7 clinic visits + two colonoscopies)

Patient Population:  Adult patients with mild to moderate Ulcerative Colitis

Study Intervention:  SER-287 Investigational Microbiome Drug

Possibility of Placebo:  1 in 3


Enrolling: Will Begin Enrollment near the end of 2020

Principle Investigator: Sashidhar Sagi, MD

Duration: 15 months (with the option of an additional 2 years of treatment after)

Patient Population:  Adult patients with moderate to severe Ulcerative Colitis

Study Intervention:  Guselkumab

Possibility of Placebo: 1 in 3


Enrolling: On Hold

Principle Investigator:  Matthew Bohm, DO

Duration:  All bio-specimen collections and chart reviews will continue until 2026

Patient Population: Any patient with either Crohn’s Disease or Ulcerative Colitis

Study Intervention:  Medical chart reviews and biological specimen collection.


Enrolling: Yes

Principle Investigator:  Monika Fischer, MD

Duration:  12 months

Patient Population: Any patient with Ulcerative Colitis starting Tofacitinib (Xeljanz) for the first time as part of their standard treatment for UC.

Study Intervention:  Medical chart review and e-mail patient questionnaires (Enrollment and participation is done via phone.)