Investigators
Open Research Studies for Diabetes
A Prospective Study to Establish a New Onset Hyperglycemia and Diabetes (NOD) Cohort
Enrolling: No
Principle Investigator: Zeb Saeed, MD
Primary Objective:
To prospectively assemble a cohort of subjects ≥50 and ≤85 years of age with New-onset Hyperglycemia and Diabetes (NOD), called the NOD Cohort, in order to:
- Estimate the probability of pancreatic ductal adenocarcinoma (PDAC) in the NOD Cohort
- Establish a biobank of clinically annotated biospecimens including a reference set of biospecimens from pre-symptomatic PDAC and control new-onset Hyperglycemia and type 2 Diabetes Mellitus (DM) subjects
- Facilitate validation of emerging tests for identifying NOD subjects at high risk for having PDAC using the reference set
A Prospective, Randomized, Double-Blind, Sham-Controlled, Multi-Center Pivotal Study to Evaluate the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita System in Subjects With Type 2 Diabetes on Insulin Therapy
Enrolling: Yes
Principle Investigators: Mark Gromski, MD, Zeb Saeed, MD, Raj Vuppalanchi, MD
Primary Outcome Measurement: Percentage of subjects who achieve a HbA1c ≤ 7.0% at Week 24 without the need for insulin at Week 24, DMR vs Sham.