5034-Vuppalanchi, Raj

Raj Vuppalanchi, M.D.

Professor of Medicine

Director of Hepatology

Associate Program Director

702 Rotary Circle, Suite 225

Indianapolis , IN 46202
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Dr. Raj Vuppalanchi is a tenured Professor of Medicine and holds the position of Director of Hepatology. He became a part of the division in 2007 following the successful completion of dual fellowships in Clinical Pharmacology and Gastroenterology/Hepatology at Indiana University School of Medicine. With extensive clinical experience, he continues to provide comprehensive care for patients grappling with various liver disorders at the Digestive and Liver Disorder Clinic, located at Indiana University Hospital.

His research primarily revolves around patient-centered approaches, with a specific focus on advancing innovative therapies for conditions such as metabolic dysfunction-associated steatohepatitis (MASH), cholestatic and autoimmune liver diseases (including PSC, PBC, and AIH), and cirrhosis. Dr. Vuppalanchi has made notable contributions in the field of non-invasive tests for assessing the severity of liver disease, employing techniques like transient elastography for liver and spleen stiffness measurements.

Moreover, he has published in the field of hepatic safety of pharmaceuticals, as well as herbal and dietary supplements. Dr. Vuppalanchi serves as a principal clinical investigator for both industry-driven and NIH-sponsored multi-center clinical trials, notably contributing to initiatives led by the NASH Clinical Research Network (NASH CRN) and the Drug-Induced Liver Injury Network (DILIN). In addition, he assumes the pivotal role of being the primary investigator for the Indiana Clinical and Translational Sciences Institute's (CTSI) Phase I clinical trials, with a specialized focus on hepatic impairment clinical trials. Dr. Vuppalanchi's comprehensive contributions to hepatology exemplify his unwavering dedication to advancing clinical knowledge and therapeutic interventions in liver disorders.

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