Raj Vuppalanchi, M.D.
Professor of Medicine
Director of Hepatology
Associate Program Director
Bio
Dr. Raj Vuppalanchi is a tenured Professor of Medicine and holds the position of Director of Hepatology. He became a part of the division in 2007 following the successful completion of dual fellowships in Clinical Pharmacology and Gastroenterology/Hepatology at Indiana University School of Medicine. With extensive clinical experience, he continues to provide comprehensive care for patients grappling with various liver disorders at the Digestive and Liver Disorder Clinic, located at Indiana University Hospital.
His research primarily revolves around patient-centered approaches, with a specific focus on advancing innovative therapies for conditions such as metabolic dysfunction-associated steatohepatitis (MASH), cholestatic and autoimmune liver diseases (including PSC, PBC, and AIH), and cirrhosis. Dr. Vuppalanchi has made notable contributions in the field of non-invasive tests for assessing the severity of liver disease, employing techniques like transient elastography for liver and spleen stiffness measurements.
Moreover, he has published in the field of hepatic safety of pharmaceuticals, as well as herbal and dietary supplements. Dr. Vuppalanchi serves as a principal clinical investigator for both industry-driven and NIH-sponsored multi-center clinical trials, notably contributing to initiatives led by the NASH Clinical Research Network (NASH CRN) and the Drug-Induced Liver Injury Network (DILIN). In addition, he assumes the pivotal role of being the primary investigator for the Indiana Clinical and Translational Sciences Institute's (CTSI) Phase I clinical trials, with a specialized focus on hepatic impairment clinical trials. Dr. Vuppalanchi's comprehensive contributions to hepatology exemplify his unwavering dedication to advancing clinical knowledge and therapeutic interventions in liver disorders.
Year | Degree | Institution |
---|---|---|
2007 | Fellowship | IU School of Medicine, Indianapolis, IN |
2005 | Fellowship | IU School of Medicine, Indianapolis, IN |
2003 | Residency | Long Island College Hospital, Brooklyn, NY |
1998 | MB,BS | Gandhi Medical College |
His research interests include pathogenesis and therapy for nonalcoholic steatohepatitis (NASH) and drug induced liver injury (DILI). His other research interests include studying alterations in drug metabolism in patients who underwent gastric bypass and patients who have cirrhosis. He is currently working on understanding the pathogenesis and treatment of muscle cramps in patients with cirrhosis.
Eadon MT; Rosenman MB; Zhang P; Fulton CR; Callaghan JT; Holmes AM; Levy KD; Gupta SK; Haas DM; Vuppalanchi R; Benson EA; Kreutz RP; Tillman EM; Shugg T; Pierson RC; Gufford BT; Pratt VM; Zang Y; Desta Z; Dexter PR; Skaar TC; The pharmacogenomics journal 2023 Sep 9
Sanyal AJ; Shankar SS; Yates KP; Bolognese J; Daly E; Dehn CA; Neuschwander-Tetri B; Kowdley K; Vuppalanchi R; Behling C; Tonascia J; Samir A; Sirlin C; Sherlock SP; Fowler K; Heymann H; Kamphaus TN; Loomba R; Calle RA; Nature medicine 2023 Sep 7
Murillo Perez CF; Ioannou S; Hassanally I; Trivedi PJ; Corpechot C; van der Meer AJ; Lammers WJ; Battezzati PM; Lindor KD; Nevens F; Kowdley KV; Bruns T; Cazzagon N; Floreani A; Mason AL; Gulamhusein A; Ponsioen CY; Carbone M; Lleo A; Mayo MJ; Dalekos GN; Gatselis NK; Thorburn D; Verhelst X; Parés A; Londoño MC; Janssen HLA; Invernizzi P; Vuppalanchi R; Hirschfield GM; Hansen BE; Levy C; Global PBC Study Group; Liver international : official journal of the International Association for the Study of the Liver 2023 May 8
Noureddin M; Mena E; Vuppalanchi R; Samala N; Wong M; Pacheco F; Polanco P; Sakkal C; Antaramian A; Chang D; Noureddin N; Kohli A; Harrison SA; Gawrieh S; Alkhouri N; Truong E; Hepatology communications 2023 May 4
Chalasani N; Vuppalanchi R; Lammert C; Gawrieh S; Braun JV; Zhuang J; Ibarra A; Ross DA; Nerenberg M; Quake SR; Sninsky JJ; Toden S; Hepatology communications 2023 May 23
Sarkis Y; Saleem N; Vuppalanchi R; Gromski M; Hepatic medicine : evidence and research 2023 Mar 28
Vuppalanchi R; Are V; Telford A; Young L; Mouchti S; Ferreira C; Kettler C; Gromski M; Akisik F; Chalasani N; JHEP reports : innovation in hepatology 2023 Jun 29
Culver A; Hamang M; Wang Y; Jiang H; Yanum J; White E; Gawrieh S; Vuppalanchi RK; Chalasani NP; Dai G; Yaden BC; Biomedicines 2023 Jul 6
Vilar-Gomez E; Vuppalanchi R; Gawrieh S; Samala N; Chalasani N; Hepatology (Baltimore, Md.) 2023 Jan 3
Vilar-Gomez E; Vuppalanchi R; Gawrieh S; Pike F; Samala N; Chalasani N; The American journal of gastroenterology 2023 Feb 16
Orman ES; Desai AP; Ghabril MS; Nephew LD; Patidar KR; Holden J; Samala NR; Gawrieh S; Vuppalanchi R; Sozio M; Lacerda M; Vilar-Gomez E; Lammert C; Liangpunsakul S; Crabb D; Masuoka H; Dakhoul L; Pan M; Gao S; Chalasani N; The American journal of gastroenterology 2023 Aug 7
Kowdley KV; Bowlus CL; Levy C; Mayo MJ; Pratt DS; Vuppalanchi R; Younossi ZM; The American journal of gastroenterology 2022 Sep 21
Halegoua-DeMarzio D; Navarro V; Ahmad J; Avula B; Barnhart H; Barritt AS; Bonkovsky HL; Fontana RJ; Ghabril MS; Hoofnagle JH; Khan IA; Kleiner DE; Phillips E; Stolz A; Vuppalanchi R; The American journal of medicine 2022 Oct 14
Wong VW; Tak WY; Goh GBB; Cheng PN; Lawitz EJ; Younossi ZM; Vuppalanchi R; Younes Z; Alkhouri N; Wang L; Liu J; Kersey K; Myers RP; Harrison SA; Goodman Z; Trauner M; Romero-Gomez M; Anstee QM; Nguyen MH; Okanoue T; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2022 Jan 22
Vuppalanchi R; Karpen SJ; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2022 Dec 11
Vilar-Gomez E; Vuppalanchi R; Mladenovic A; Samala N; Gawrieh S; Newsome PN; Chalasani N; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2021 Dec 25
S-Are V; Yoder L; Samala N; Nephew L; Lammert C; Vuppalanchi R; Annals of hepatology 2020 Sep 12
Dr. Vuppalanchi's clinical interests include management of cirrhosis, non-alcoholic fatty liver, chronic hepatitis C and B, primary biliary cirrhosis, primary sclerosing cholangitis, alcoholic liver disease and drug induced liver injury.
Desc: Trustee Teaching Award
Scope: University
Date: 2017-05-01