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Faculty

By carefully selecting training faculty, the Medical Scientist Training Program is able to provide the best possible research experience that propels students toward success as physician scientists and physician engineers. Training faculty are chosen amongst the graduate faculty at IU School of Medicine and the Weldon School of Biomedical Engineering at Purdue. Faculty are members of both basic science and clinical departments and represent areas of strengths amid both institutions.

Criteria for these faculty include a track record in training pre-doctoral PhD or MD-PhD students, evidence of high-quality research as judged by peer-reviewed publications, and extramural peer reviewed funding.

Program Co-Directors

43800-Gaston, Benjamin

Benjamin Gaston, MD

Billie Lou Wood Professor of Pediatrics

Dr. Gaston is a physician-scientist who has been continuously funded by NIH for over 20 years. He is currently principal investigator on a Program Project Grant and several other NIH grants. Trainees are involved in each of these projects. He is particularly focused on translating basic science discoveries from his group into therapies and diagnostic tools relevant to respiratory medicine. Specific projects include new therapies for severe asthma and other obstructive lung diseases; and for opioid-induced respiratory depression and other causes of apnea. Novel diagnostics include technologies for measuring airway inflammation and vascular S-nitrosothiol delivery. In recent work, he has discovered an important role for pulmonary androgen receptor expression in asthma; this appears to have important therapeutic implications. Recent discoveries also include the role of the voltage-gated potassium channel in stereoselective S-nitrosocysteine signaling.

Dr. Gaston went to medical school at the University of Virginia. He served in the US Navy aboard the USS Iwo Jima and at Naval Hospital, Camp Lejeune. He developed a keen interest in studying respiratory diseases when he was a general pediatrician. He did a research-intensive fellowship at Boston Children’s Hospital. Since then, he has had over 190 publications and is an inventor on many patents. He has helped to start five companies that are currently active. He has trained over 20 pre-doctoral students and mentored over 25 successful post-doctoral trainees. He is currently Vice Chair for Translational Research at the Riley Children’s Hospital, the IU Department of Pediatrics and the Wells Center for Pediatric Research; and he has a pediatric pulmonology practice at Riley.

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3060-Herbert, Brittney-Shea

Brittney-Shea Herbert, PhD

Assistant Dean for Physician Scientist Development

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Program Associate Directors

5100-Evans-Molina, Carmella

Carmella Evans-Molina, PhD, MD

Director, Indiana Diabetes Research Center

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Program Advisor

Associate Program Director Sherry Harbin, PhD, of the MD PhD Program

Sherry Harbin, PhD

Professor of Biomedical Engineering and Basic Medical Sciences - Purdue University

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9949-Clapp, D.

D. W. Clapp, MD

Chair, Department of Pediatrics

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Cancer and Hematologic Disease

9949-Clapp, D.

D. W. Clapp, MD

Chair, Department of Pediatrics

The Clapp lab focuses on the molecular pathogenesis of neurofibromatosis type 1 and neurofibromatosis type 2. A major effort in the laboratory is understanding the genetic, biochemical and cell-cell interactions that lead to the genesis and progression of plexiform neurofibromas that are often congenital in origin and become clinically apparent in babies and young children.

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26940-Dave, Utpal

Utpal Dave, MD

Associate Professor of Medicine

The Dave lab is committed to understanding basic aspects of oncogene function, which should lead to novel therapeutic approaches for difficult-to-treat cancers. They study two oncogenic pathways in the pathogenesis of T-cell leukemias and lymphomas.

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11378-Fehrenbacher, Jill

Jill C. Fehrenbacher, PhD

Associate Professor of Pharmacology & Toxicology

The long-term goal of the Fehrenbacher lab is to understand how diseases and drugs can modulate the function of peripheral sensory neurons to underlie clinical neuronal dysfunction. In addition, they also are interested in how sensory neuron function can alter cancer growth and metastasis.

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13517-Kapur, Reuben

Reuben Kapur, PhD

Frieda and Albrecht Kipp Professor of Pediatrics

Dr. Kapur's lab focuses on understanding the mechanisms of childhood leukemias including acute myeloid leukemias, Juvenile myelomoncytic leukemias and pediatric bone marrow failure syndromes such as Fanconi Anemia and Diamond Blackfan Anemia. The ultimate goal of Dr. Kapur's work is to develop novel therapies for the treatment of these diseases.

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13975-Kelley, Mark

Mark R. Kelley, PhD

Betty and Earl Herr Professor of Pediatric Oncology Research

Dr. Kelley's work has focused on translational research in DNA damage and repair, specifically, to determine how those activities can be exploited therapeutically to treat cancers and protect normal cells from oxidative and DNA base damage.

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196-Liu, Yunlong

Yunlong Liu, PhD

Director, Center for Computational Biology & Bioinformatics

The Liu lab (Laboratory for Computational Genomics) uses systems biology approaches to understand regulatory mechanisms of gene expression, including transcriptional regulation, post-transcriptional regulation, and epigenetic regulation.

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21607-Lu, Tao

Tao Lu, PhD

Associate Professor of Pharmacology & Toxicology

The Lu lab research centers on the multi-functional transcription factor nuclear factor κB (NF-κB). As a hallmark in many cancers and a key link between inflammation and cancer, the pivotal transcription factor NF-κB is a “hot” target for disease treatment. The lab's research focuses on addressing how NF-κB is regulated and how this regulation contributes to tumorigenesis.

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14059-Mayo, Lindsey

Lindsey D. Mayo, PhD

Associate Professor of Pediatrics

The Mayo lab has continued to make novel discoveries in the area of Mdm2, p53 and PTEN related to the regulation of their respective activity and how that relates to the tumor microenvironment.

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20748-Mosley, Amber

Amber L. Mosley, PhD

Associate Professor of Biochemistry & Molecular Biology

The Mosley lab is focused on the regulation of RNA Polymerase II elongation and termination using systems level approaches including next-generation sequencing and protein mass spectrometry.

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6511-Paczesny, Sophie

Sophie Paczesny, MD, PhD

Adjunct Professor of Pediatrics

The focus of the Paczesny lab is research of discovery and validation of biomarkers of complications post-transplantation as well as bring new targeted therapies to the clinic and explore novel pathways in GVHD.

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13544-Pollok, Karen

Karen E. Pollok, PhD

Associate Professor of Pediatrics

The Pollok lab focuses on the development of novel multi-phase therapies that target primary and secondary treatment response networks. To evaluate mechanisms of action and efficacy, 3D cultures, patient-derived xenografts, and orthotopic modeling approaches are being utilized.

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6480-Renbarger, Jamie

Jamie L. Renbarger, MD

Caroline Symmes Professor of Pediatric Cancer Research

The Renbarger lab research involves a major effort to identify biomarkers of drug toxicity and efficacy in the treatment of pediatric cancers. The ultimate goal is to use these biomarkers to develop simple, robust and practical clinical predictors of response to medications in individual patients that can be used to optimize dosing in the treatment of children, many of whom have curable malignancies.

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5060-Turchi, John

John J. Turchi, PhD

Tom and Julie Wood Family Foundation Professor of Lung Cancer Research

The Turchi lab research is focused on determining the molecular mechanism by which cisplatin imparts its efficacy. They are involved in the identification and development of agents that target specific proteins involved in cisplatin metabolism with the goal of enhancing cisplatin activity in tumors and cancer types that typically do not respond well to cisplatin. They are also involved in research geared towards understanding the interaction of cisplatin and ionizing radiation and how this treatment regimen influences DNA repair pathways.

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43871-Yeh, Elizabeth

Elizabeth S. Yeh, PhD

Associate Professor of Pharmacology & Toxicology

Research in the Yeh Lab focuses on the study of a protein kinase called HUNK, which stands for Hormonally Upregulated Neu-associated Kinase. Prior studies in the lab indicate a role for HUNK in refractory HER2-positive breast cancer as well as in the development of metastatic breast cancer.

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Cardiovascular and Kidney Disease

5054-Basile, David

David P. Basile, PhD

Professor of Anatomy, Cell Biology & Physiology

Work in the Basile lab has been directed toward elucidating the pathophysiology of acute kidney injury and chronic kidney disease. Since 2001, the lab has focused on studying the functional chronic consequences of acute kidney injury with particular questions related to the altered vasculature.

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4912-Dagher, Pierre

Pierre C. Dagher, MD

Professor of Medicine

The Dagher lab investigates the mechanisms of acute kidney injury (AKI) in animal models of renal ischemia- reperfusion and sepsis. In particular, they study the interplay between tubular apoptosis, inflammation, metabolism and innate immunity in shaping the renal response to injury and therapy.

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4906-Field, Loren

Loren J. Field, PhD

Distinguished Professor

Dr. Field and his IU colleagues were the first to show that relatively simple genetic modifications can induce mammalian heart cells to regenerate. His current research is focused on identify genes and molecules that promote heart muscle regeneration by coaxing healthy cells to proliferate. The success of this research would offer the potential for seriously ill patients whose tissue has been damaged by heart attack to "re-grow" their own hearts.

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15691-Firulli, Anthony

Anthony B. Firulli, PhD

Carleton Buehl McCulloch Professor of Pediatrics

Dr. Firulli's career focus has been on gaining an understanding of the role that the bHLH Hand/Twist-family of proteins plays during heart development. His lab group has established that these factors have broad dimerization characteristics and that phosphoregulation of these proteins helps define bHLH partner choice.

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4976-Moe, Sharon

Sharon M. Moe, MD

Associate Dean for Clinical and Translational Research

The Moe lab investigates the relationship of kidney disease, vascular calcification, bone, and disorders of mineral metabolism known as CKD-Mineral Bone Disorder (CKD-MBD). Their research is funded by the NIH, Veterans Administration, Food and Drug Administration, and industry and utilizes in vivo, ex vivo and in vitro techniques to investigate the pathophysiology of arterial medial calcification and bone disease.

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4981-Molitoris, Bruce

Bruce A. Molitoris, MD

Distinguished Professor

The Molitoris lab has dedicated their time toward the study of acute kidney injury (AKI) from both ischemic and nephrotoxic compounds, primarily secondary to aminoglycosides. They have helped to understand mechanistically, and developed therapeutically, many potential approaches for acute kidney injury.

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6504-Sturek, Michael

Michael Sturek, PhD

Professor of Anatomy, Cell Biology & Physiology

The general aim of the Sturek lab is to understand cellular and molecular Ca signaling mechanism for in vivo cardiovascular phenomena. Their research encompasses experimental approaches at all levels – clinical, whole animal, organ, tissue, cell, and molecular.

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22816-Ware, Stephanie

Stephanie Ware, MD, PhD

Professor of Pediatrics

The Ware lab has research programs that focus on the genetic and developmental basis of pediatric heart disease. The two main areas of interest are disorders of cardiac function (cardiomyopathies) and structure (congenital heart disease).

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Diabetes and Metabolism

20977-Corson, Timothy

Timothy W. Corson, PhD

Associate Professor of Ophthalmology

The Corson lab applies chemical biology to problems in vision science. The lab uses a wide variety of techniques, including high-throughput compound screening, novel compound development, and biochemical approaches to compound mechanism of action as well as more traditional techniques, including tissue culture, expression analyses, in vivo modeling, and molecular biology.

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19563-Dong, X

X C. Dong, PhD

Professor of Biochemistry & Molecular Biology

The Dong lab is studying the mechanisms regulating nutrient homeostasis, energy expenditure, cell signaling, gene transcription, epigenetic control of chromatin remodeling in normal physiology, aging, cancer, diabetes, obesity, and alcoholic and non-alcoholic fatty liver diseases.

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13333-Elmendorf, Jeffrey

Jeffrey S. Elmendorf, PhD

Associate Professor of Anatomy, Cell Biology & Physiology

The Elmendorf lab dissects mechanisms of insulin action that regulate glucose uptake by fat and muscle cells, and defines defects contributing to insulin resistance associated with obesity and type 2 diabetes.

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5100-Evans-Molina, Carmella

Carmella Evans-Molina, PhD, MD

Director, Indiana Diabetes Research Center

The goals of the Evans-Molina lab are (1) to define the molecular and inflammatory etiologies of b cell dysfunction in Type 1 and Type 2 diabetes and (2) to identify novel stem cell based strategies to improve b cell survival in diabetes. The goal of the translational arm of this research program is to define and validate novel serum biomarkers that identify early b cell stress in clinically silent Type 1 diabetes.

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9738-Hurley, Thomas

Thomas D. Hurley, PhD

Associate Dean for Graduate Education

The major focus of the Hurley lab is to understand, at the molecular level, the processes involved in the recognition and binding of molecules that are directed to the active sites of enzymes.

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26337-Linnemann, Amelia

Amelia K. Linnemann, PhD

Assistant Professor of Pediatrics

The primary focus of the Linnemann lab is to understand mechanisms of pancreatic β-cell death/survival, islet compensatory adaptation to cellular stress, and how these factors contribute to diabetes pathogenesis.

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26336-Ren, Hongxia

Hongxia Ren, PhD

Assistant Professor of Pediatrics

The primary focus of the Ren lab is to study the metabolic fundtion of Gpr17 in the gasstrointestinal tract.

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15102-Roach, Peter

Peter J. Roach, PhD

Distinguished Professor

The Roach lab is primarily focused on the metabolism of glycogen, its regulation, and the clinical consequences of its defects, as exhibited in glycogen storage diseases (glycogenoses).

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18596-Sims, Emily

Emily K. Sims, MD

Assistant Professor of Pediatrics

My primary focus of the Sims lab lies in identifying and understanding risk factors predisposing susceptible individuals to diabetes development, with an ultimate goal of improved risk prediction and development of novel treatments to predict or slow progression of diabetes.

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15110-Wek, Ronald

Ronald C. Wek, PhD

Showalter Professor of Biochemistry

The Wek lab addresses how cells cope with stress. This research is important for the development of new strategies for the diagnosis and treatment of diabetes and related metabolic disorders, skin disorders, infectious diseases, cancers, and neuropathologies.

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22650-Zimmers, Teresa

Teresa A. Zimmers, PhD

H.H. Gregg Professor of Cancer Research

The Zimmers lab seeks to fill the knowledge gap regarding the molecular and cellular pathways leading to weight loss and dysmetabolism in cachexia by using novel animal models and correlative phenotypic and molecular data from patients to identify molecular, cellular and organ system mechanisms leading to cachexia.

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Immunology and Microbiology

20638-Androphy, Elliot

Elliot J. Androphy, MD

Chair, Department of Dermatology

The Androphy lab studies molecular biology and oncogenic properties of papillomaviruses.

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21736-Arrizabalaga, Gustavo

Gustavo A. Arrizabalaga, PhD

Assistant Dean for Diversity Affairs

The Arrizabalaga lab focuses on various aspects of the cellular and molecular biology of the protozoan parasite Toxoplasma gondii.

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14633-Brutkiewicz, Randy

Randy R. Brutkiewicz, PhD

Professor of Microbiology & Immunology

The Brutkiewicz lab studies immune evasion by microbial pathogens and tumors, as well as the regulation of antigen presentation by various signal transduction pathways, in both innate and adaptive immune responses.

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4848-Gupta, Samir

Samir K. Gupta, MD

Professor of Medicine

The Gupta lab is active in the general field of HIV therapeutics and complications.

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13430-Harrington, Maureen

Maureen A. Harrington, PhD

Associate Dean for Medical Student Education, Foundational Sciences

Studies underway in the Harrington lab are focused on determining the molecular mechanism through which SIMPL mediates the synergistic enhancement of p65 activity.

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906-Kaplan, Mark

Mark H. Kaplan, PhD

Chair, Department of Microbiology & Immunology

The Kaplan lab studies transcription factors that are involved in the development of T helper cell subsets and how those cells contribute to inflammation in allergic and autoimmune diseases.

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5018-Nelson, David

David E. Nelson, PhD

Professor of Microbiology & Immunology

The Nelson lab is focused on chlamydial pathogenesis, microbiome pathogen interactions and pathogen discovery.

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13502-Sullivan, William

William J. Sullivan, PhD

Showalter Professor of Pharmacology & Toxicology

The Sullivan lab studies cellular signaling and the regulation of gene expression in a protozoan parasites Plasmodium (malaria) called Toxoplasma. Transmitted by cats and contaminated food/water, Toxoplasma causes congenital birth defects as well as opportunistic infection in immune compromised patients.

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13357-Tepper, Robert

Robert S. Tepper, MD, PhD

Mary Agnes Kennedy and Katheryn Kennedy Weinberger Professor of Pediatrics

The Tepper lab focuses on lung structure and function as it relates to airway hyper-reactivity, as well as lung growth and development.

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6507-Yu, Andy

Andy Q. Yu, MD, PhD

Professor of Microbiology & Immunology

Research in the Yu lab is centered on HIV immunopathogenesis, latency, and eradication, and the clinical and immunological interactions between HIV and other human persistent viruses like HBV and HCV.

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18402-Zhou, Baohua

Baohua Zhou, PhD

Associate Professor of Pediatrics

The Zhou lab studies the development and function of effector T helper (Th) cells and regulatory T (Treg) cells, and their impact on immune mediated inflammatory diseases.

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Musculoskeletal Disease

5035-Allen, Matthew

Matthew R. Allen, PhD

Assistant Dean for Faculty Affairs and Professional Development

The Allen lab studies the tissue-level mechanisms responsible for musculoskeletal integrity in health and disease by utilizing numerous in vivo model systems that help investigators understand how disease and pharmaceutical intervention influence bone structure, cellular activity, tissue-level properties (such as mineralization, microdamage, collagen, hydration), and biomechanical properties.

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26803-Bonewald, Lynda

Lynda F. Bonewald, PhD

Director, Indiana Center for Musculoskeletal Health

The Bonewald lab focuses on the biology and function of the osteocyte. Investigators in this lab have two major focus areas: the crosstalk between osteocyte and muscle and the role of the osteocyte in calcium homeostasis under calcium demanding conditions.

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13418-Hashino, Eri

Eri Hashino, PhD

Ruth C. Holton Professor of Otology

The Hashino lab is one of three faculty research labs within the 3D Stem Cell Biology Research Group at Indiana University School of Medicine. Leading investigators within the group discovered a three-dimensional (3D) culture method for deriving mini inner ear organs, called inner ear organoids, which contain the sensory cells to the inner ear and function similarly to native inner ear organs.

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18628-Kacena, Melissa

Melissa A. Kacena, PhD

Professor of Orthopaedic Surgery

The Kacena lab is exploring the interaction of the bone and hematopoietic systems, thereby potentially improving the treatment of metabolic bone disease, hematopoietic disorders and fracture healing.

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17979-Obukhov, Alexander

Alexander G. Obukhov, PhD

Associate Professor of Anatomy, Cell Biology & Physiology

The Obukhov lab currently focuses on establishing the role of TRPC channels in the metabolic syndrome-associated atherosclerosis using the Ossabaw pig model. The other projects investigate the mechanisms regulating the contractility of the uterus, the mechanisms underlying endothelial dysfunction in a mouse aorta model, traumatic brain injury-associated vascular dysfunction, diabetic neuropathy, catecholamine secretion regulation in adrenal chromaffin cells, and the function of SLC4A11 transporters in the corneal endothelium.

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19291-Plotkin, Lilian

Lilian I. Plotkin, PhD

Professor of Anatomy, Cell Biology & Physiology

The Plotkin lab focuses on the role of connexins in the transduction of signals induced by hormonal, pharmacotherapeutic and mechanical stimuli in osteoblasts and osteocytes. For this, the laboratory utilizes in vitro techniques including tissue culture, analysis of protein expression by Western blotting and of gene expression by real time PCR.

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10972-Robling, Alexander

Alexander G. Robling, PhD

Chair, Anatomy, Cell Biology & Physiology

The Robling lab seeks to discover the molecular mechanisms by which bone tissue senses mechanical loading, by studying how several signal transduction pathways affect bone accumulation, and how cellular activity is altered by mechanical stimulation. This goal is addressed by investigating bone cell proliferation, differentiation and apoptosis, after mechanical loading in mice harboring various mutations in the Wnt/Akt/Bmp signaling pathways.

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5147-Roodman, G. David

G. David D. Roodman, MD, PhD

Distinguished Professor

The Roodman lab focuses on osteoclasts and osteoblast activity in both normal and pathological states including Paget’s disease and Multiple Myeloma.

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23070-Sankar, Uma

Uma Sankar, PhD

Associate Professor of Anatomy, Cell Biology & Physiology

The Sankar lab uses global and conditional knockout mouse models, biochemical, molecular biology and cell biology techniques as well as pharmacological inhibitors to investigate the mechanisms by which members of the Calcium/calmodulin dependent protein kinase (CaMK) signaling cascade, CaMKK2 along with its downstream kinases AMPK, CaMKI and CaMKIV; regulate the fate and function of bone marrow-derived mesenchymal stem cells, osteoblasts and osteoclasts.

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1931-White, Kenneth

Kenneth E. White, PhD

Chancellor's Professor

The White lab is studying the molecular genetics of metabolic bone diseases involving the osteocyte-derived hormone fibroblast growth factor-23 (FGF23).

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Neuroscience

18765-Atwood, Brady

Brady K. Atwood, PhD

Assistant Professor of Pharmacology & Toxicology

The Atwood lab is focused on understanding the functions of specific synapses in the brain and how these functions are impacted in disease states.

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15856-Brustovetsky, Nickolay

Nickolay Brustovetsky, PhD

Professor of Pharmacology & Toxicology

The Brustovetsky lab studies the mechanisms of mitochondrial dysfunction, calcium deregulation, and neuronal loss in neurodegeneration such as Huntington’s disease.

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276-Foroud, Tatiana

Tatiana Foroud, PhD

Executive Associate Dean for Research Affairs

The central focus of the Foroud lab is the identification of genes contributing to disease. Research is currently focused on a variety of complex disorders including Parkinson disease, Alzheimer disease, intracranial aneurysms, alcohol dependence, and cancer.

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20178-Hoang, Quyen

Quyen Q. Hoang, PhD

Associate Professor of Biochemistry & Molecular Biology

The Hoang lab applies a broad range of methodologies to investigate the molecular mechanisms of Parkinson’s disease and other neurodegenerative diseases.

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20790-Jones, Kathryn

Kathryn J. Jones, PhD

Professor of Anatomy, Cell Biology & Physiology

The Jones lab focuses on neural Injury and repair; gonadal steroids as neurotherapeutics; neuroimmunology; and ALS.

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41977-Kim, Jungsu

Jungsu Kim, PhD

P. Michael Conneally Professor of Medical and Molecular Genetics

The Kim lab is interested in understanding the molecular and cellular basis of neuronal and glial dysfunction in Alzheimer’s disease, other aging-associated neurodegenerative diseases, and normal brain aging.

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27243-Landreth, Gary

Gary E. Landreth, PhD

Martin Professor of Alzheimer's Research

The Landreth lab focuses on the biological basis of Alzheimer’s disease (AD)—specifically how genetic risks factor influence disease pathogenesis. The work in the laboratory employs contemporary animal models of AD.

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13390-Lahiri, Debomoy

Debomoy K. Lahiri, PhD

Distinguished Professor

The Lahiri lab main research interest is to understand how degeneration of brain cells under laboratory conditions can be more closely made to resemble the “natural” neurodegeneration of Alzheimer's Disease (AD). This can be used to test drugs to prevent or even reverse AD-related degeneration. In particular, they are most interested in how stress from the environment leads to brain nerve cell damage in AD.

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23627-Lamb, Bruce

Bruce T. Lamb, PhD

Executive Director, Paul and Carole Stark Neurosciences Research Institute

Dr. Lamb’s lab works on the basic science of Alzheimer’s disease, with a focus on: genetic modifiers identified from mouse and human studies; animal models of Alzheimer’s disease (including Director of the NIH-Funded Model Organism Development and Evaluation for Late-onset Alzheimer’s Disease program, MODEL-AD); microglia and neuronal-microglial communication in the development and progression of Alzheimer’s pathologies; traumatic brain injury as an environmental modifier for the development of Alzheimer’s pathologies; and Alzheimer’s disease drug discovery as Co-Director of the NIH-Funded IU School of Medicine/Purdue UniversityTarget Enablement to Advance Therapy Development for Alzheimer’s Disease (TREAT-AD) Center.

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25526-Meyer, Jason

Jason Meyer, PhD

Associate Professor of Medical & Molecular Genetics

The Meyer lab focuses on mechanisms of neural development and neurodegeneration using human pluripotent stem cell-derived neurons. Fundamentally, the research emphasizes the in vitro three dimensional organization and differentiation of these stem cells into organoids which serve as a model of the temporal and spatial organization of neural tissue. From these organoids, different individual cell types are isolated and utilized for studies of neurodegeneration.

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22290-McAllister, Thomas

Thomas W. McAllister, MD

Chair, Department of Psychiatry

The McAllister lab has focused on characterizing the biomechanical basis of concussion, and the effects of repetitive head impacts on brain structure and function in contact sport athletes.

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6962-Saykin, Andrew

Andrew J. Saykin, Psy.D.

Director, Center for Neuroimaging

The Saykin lab uses brain imaging and genomic methods to study mechanisms of memory dysfunction and treatment response in neurological and psychiatric disorders. Current research examines advanced imaging methods for early preclinical detection of Alzheimer’s, the neural basis of cancer chemotherapy-induced cognitive changes and the alterations in brain activity and connectivity in schizophrenia.

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15720-Truitt, William

William A. Truitt, PhD

Associate Professor of Anatomy, Cell Biology & Physiology

The Truitt lab is focused on determining how social interactions can be used to overcome anxiety. The lab team hopes to contribute to elucidating the neural mechanism by which psychotherapy helps patients overcome anxiety.

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20353-White, Fletcher

Fletcher A. White, PhD

Vergil K. Stoelting Professor of Anesthesia

Research in the White lab focuses on the mechanistic development and chronicity of pain due to traumatic brain injury (TBI), peripheral nerve injury, polytrauma, chemotherapeutics and disease.

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23323-Yamamoto, Bryan

Bryan K. Yamamoto, PhD

Chair, Department of Pharmacology & Toxicology

Research in the Yamamoto lab over the last 27 years has focused on how drugs of abuse affect the neurochemistry of brain. The lab has studied how amphetamines and their interaction with stress and the immune system alter the blood-brain barrier, brain neurochemistry, and produce damage to regions of the brain that are critically involved in controlling movement and memory processes.

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6553-Yoder, Karmen

Karmen K. Yoder, PhD

Professor of Radiology & Imaging Sciences

Dr. Yoder’s research interests have expanded to other cutting-edge in vivo magnetic resonance (MR) neuroimaging methods such as functional connectivity, structural connectivity, and magnetic resonance spectroscopy, with the ultimate goal of developing sound multi-modality (i.e., PET, MR) data analyses approaches that will better inform how neurochemical systems are regulated in the brain.

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