4931-Twigg III, Homer

Homer L. Twigg III, MD

Floyd and Reba Smith Professor of Pulmonary Disease

Professor of Medicine

Address
Willis Gatch Hall, CL 260
1120 W. Michigan St.
CL 260
Indianapolis, IN 46202
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Bio

Homer L. Twigg III, M.D. is a Professor of Medicine in the Pulmonary, Allergy, Critical Care, and Sleep Medicine Division at Indiana University. Dr. Twigg did his Medical School training at Georgetown University, Internal Medicine Residency at the University of Alabama at Birmingham, and Pulmonary/Critical Care Fellowship at the University of Texas Health Science Center at Dallas (Parkland). He joined the faculty at Indiana University in 1989 and served as the Chief of the Division 2000 to 2017. Dr. Twigg has a long research interest in pulmonary host defense in HIV infection and has served on many special emphasis panels sponsored by the NHLBI in this area. He also served a term as a standing member of the Lung Cellular, Molecular, and Immunobiology (LCMI) study section.  Most recently Dr. Twigg has been investigating the lung Microbiome and Virome in healthy subjects and patients with HIV infection, attempting to link the microbial milieu to chronic inflammation and chronic diseases found in the HIV-infected and aging population.

Key Publications

Effect of highly active antiretroviral therapy on viral burden in the lungs of HIV-infected subjects.
Twigg HL III, M Weiden, F Valentine, CT Schnizlein-Bick, R Basset, L Zheng, J Wheat, RB Day, H Rominger, R Collman, L Fox, R Coombs, RP Bucy, for the Adult AIDS Clinical Trials Group Protocol 723 Team. J Inf Dis 197:109-116, 2008.
 
Impact of antiretroviral therapy on lung immunology and inflammation.
Twigg HL III, KS Knox. Clin Chest Med 34:155-164, 2013.
 
Effect of Advanced HIV Infection on the Respiratory Microbiome.
Twigg HL III, KS Knox, J Zhou, KA Crothers, DE Nelson, E Toh, RB Day, H Lin, X Gao, Q Dong, D Mi, BP Katz, E Sodergren, GM Weinstock.  Am J Respir Crit Care Med 194:226-235, 2016.
 
Lung microbiome in human immunodeficiency virus infection.
Twigg HL III, GM Weinstock, KS Knox.  Translational Research 179:97-107, 2017.
 
Refining Current Scientific Priorities and Identifying New Scientific Gaps in HIV-Related Heart, Lung, Blood, and Sleep Research.
Twigg HL III, R Crystal, J Currier, P Ridker, N Berliner, HP Kiem, G Rutherford, S Zou, S Glynn, R Wong, E Perprah, E Caler.  AIDS Res Hum Retroviruses.  33:889-897, 2017.
 

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