My work balances teaching and research on the neurobiology and genetics of aging and Alzheimer’s disease (AD). I particularly enjoy working with and teaching medical students, graduate students, residents and fellows. I also give presentations on my research at national and international conferences. My main research interest is to understand how degeneration of brain cells under laboratory conditions can be more closely made to resemble the “natural” neurodegeneration of AD. This can be used to test drugs to prevent or even reverse AD-related degeneration. In particular, I am most interested in how stress from the environment leads to brain nerve cell damage in AD.
I have published over 300 peer-reviewed articles, authored four books and received several patents, much of that in collaboration with others. I have received external grants from National Institute on Aging/NIH (R01, R03, R21, R41 and P30), the Alzheimer’s Association, and drug companies, e.g., Baxter Healthcare, Forest Research, Janssen, Novartis, and QR Pharma. I mentor Masters, PhD, MD/PhD students, and postdoctoral fellows. In my commitment to disseminate knowledge, I also serve as the Editor-In-Chief of a respected, peer-reviewed international journal, Current Alzheimer Research, which publishes articles on basic, clinical, and translational research from diverse areas of AD. I am a Core leader and member of the Indiana Alzheimer’s Disease Center (IADC) Executive Committee. I was particularly humbled to receive the Zenith Fellow Award.