
John J. Turchi, PhD
Tom and Julie Wood Family Foundation Professor of Lung Cancer Research
Professor of Medicine
Professor of Biochemistry & Molecular Biology
Bio
Dr. John J. Turchi is a professor and researcher at the Indiana University School of Medicine. He holds the Tom and Julie Wood Family Foundation Professorship in Lung Cancer Research and is a Professor of Medicine in the Division of Hematology/Oncology, as well as a Professor of Biochemistry and Molecular Biology.
Year | Degree | Institution |
---|---|---|
1993 | Postdoctoral Training | University of Rochester, Rochester, NY |
1990 | PhD | University of Missouri |
1985 | BS | Clemson University |
John Turchi's laboratory research primarily focuses on developing novel therapies for lung cancer by targeting DNA repair and DNA damage response pathways. Work in his lab involves using small drug-like molecules to inhibit sensors of DNA damage and DNA replication stress, which are crucial for cancer cell survival. By disrupting these pathways, Turchi aims to induce cell death specifically in cancer cells, offering a greater therapeutic window and reduced off-target toxicity for treatment of lung and ovarian cancer. Efforts are geared towards translating these findings from the lab to clinical applications to benefit patients with limited treatment options.
Turchi JJ; VanderVere-Carozza PS; Methods in molecular biology (Clifton, N.J.) 2019
Keller EJ; Porter M; Garrett JE; Varie M; Wang H; Pollok KE; Turchi JJ; Zaleski JM; Dynlacht JR; Radiation research 2018 May 15
Gavande NS; VanderVere-Carozza P; Mishra AK; Vernon TL; Pawelczak KS; Turchi JJ; Journal of medicinal chemistry 2017 Sep 21
Pawelczak KS; Gavande NS; VanderVere-Carozza PS; Turchi JJ; ACS chemical biology 2017 Dec 20
Sears CR; Cooney SA; Chin-Sinex H; Mendonca MS; Turchi JJ; DNA repair 2016 Mar 3
Gavande NS; VanderVere-Carozza PS; Hinshaw HD; Jalal SI; Sears CR; Pawelczak KS; Turchi JJ; Pharmacology & therapeutics 2016 Feb 16
Woods DS; Sears CR; Turchi JJ; PloS one 2015 May 15
Fang F; Munck J; Tang J; Taverna P; Wang Y; Miller DF; Pilrose J; Choy G; Azab M; Pawelczak KS; VanderVere-Carozza P; Wagner M; Lyons J; Matei D; Turchi JJ; Nephew KP; Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Oct 14
Turchi JJ; Woods DS; VanderVere-Carozza P; Cancer discovery 2014 Oct
Mishra AK; Dormi SS; Turchi AM; Woods DS; Turchi JJ; Biochemical pharmacology 2014 Nov 4
Peng X; Wang F; Li L; Bum-Erdene K; Xu D; Wang B; Sinn AA; Pollok KE; Sandusky GE; Li L; Turchi JJ; Jalal SI; Meroueh SO; Molecular bioSystems 2014 Jan 9
Xu J; Zeng LF; Shen W; Turchi JJ; Zhang ZY; Biochemical and biophysical research communications 2013 Sep 13
Yakubov B; Chelladurai B; Schmitt J; Emerson R; Turchi JJ; Matei D; Neoplasia (New York, N.Y.) 2013 Jun
Woods D; Turchi JJ; Cancer biology & therapy 2013 Feb 4
Sears CR; Turchi JJ; The Journal of biological chemistry 2012 May 23
Jalal S; Earley JN; Turchi JJ; Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Sep 9
Dynlacht JR; Batuello CN; Lopez JT; Kim KK; Turchi JJ; Radiation research 2011 Jun 23
Earley JN; Turchi JJ; Antioxidants & redox signaling 2011 Jan 23
Khanna M; Chelladurai B; Gavini A; Li L; Shao M; Courtney D; Turchi JJ; Matei D; Meroueh S; Molecular cancer therapeutics 2011 Feb 17
Neher TM; Bodenmiller D; Fitch RW; Jalal SI; Turchi JJ; Molecular cancer therapeutics 2011 Aug 16
Neher TM; Shuck SC; Liu JY; Zhang JT; Turchi JJ; ACS chemical biology 2010 Oct 15
Pawelczak KS; Turchi JJ; DNA repair 2010 Mar 27
Neher TM; Rechkunova NI; Lavrik OI; Turchi JJ; Biochemistry 2010 Feb 2
Anciano Granadillo VJ; Earley JN; Shuck SC; Georgiadis MM; Fitch RW; Turchi JJ; Journal of nucleic acids 2010 Dec 6
Pawelczak KS; Bennett SM; Turchi JJ; Antioxidants & redox signaling 2010 Dec 2
Shuck SC; Turchi JJ; Cancer research 2010 Apr 15
Bennett SM; Neher TM; Shatilla A; Turchi JJ; BMC molecular biology 2009 Aug 28
Pawelczak KS; Turchi JJ; Nucleic acids research 2008 May 31
Shuck SC; Short EA; Turchi JJ; Cell research 2008 Jan
Andrews BJ; Lehman JA; Turchi JJ; The Journal of biological chemistry 2006 Mar 13
Turchi JJ; Proceedings of the National Academy of Sciences of the United States of America 2006 Mar 13
Desc: Trustees' Teaching Award
Scope: University
Date: 2023-05-01