Research in the Department of Neurology focuses on Alzheimer’s disease, epilepsy, movement disorders, pediatric neurology, stroke and more.

Neurology Research

The Department of Neurology at Indiana School of Medicine has made great strides in transforming patient lives through comprehensive research. Built on a long tradition of work in cerebrovascular disease, the department's preclinical and clinical neurologic research programs are dynamic, multidisciplinary groups focused on improved prevention and treatment.

The department is home to the nation’s most comprehensive study of early-onset Alzheimer’s disease as well as innovative investigations in a wide array of therapeutic areas supported by federal grants from the National Institute of Neurological Disorders and Stroke (NINDS), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute on Aging (NIA), and the National Science Foundation. Faculty in this department have an extensive track record of successfully partnering with other academic medical centers throughout the United States and the pharmaceutical industry to test and refine new treatments.

Participate in Research

Want to help researchers find new ways to diagnose and treat neurologic conditions? Contact the Neurology Clinical Trials team to get connected to ongoing studies in Indiana.

Email Clinical Trials Team

130 publications in 2023
27.8 million dollars in 2023 research funding
85 clinical trials
research programs
close up of lab bench equipment

Indiana Alcohol Research Center

The Indiana Alcohol Research Center is a specialized center where experts study behavioral, genetic and central nervous system factors that contribute to alcohol-use disorders.
Learn More Indiana Alcohol Research Center


The Longitudinal Early-onset AD Study (LEADS) is funded by the National Institute on Aging to address several major gaps in Alzheimer’s disease and related dementias research.
Learn More LEADS

Neurology Clinical Trials

The Department of Neurology clinical trials program specialists help connect participants and their families with the support needed to improve both their health and quality of life.
Learn More Neurology Clinical Trials
faculty labs
liana apostolova and colleague review results on a computer monitor

Apostolova Lab

The Apostolova lab focuses on early-onset Alzheimer’s disease and the development and validation of imaging and genetics biomarkers. 
Learn More Apostolova Lab
Jeffrey Dage lab

Dage Lab

The Dage Lab is focused on the discovery and development of biomarkers to aid in the understanding of neurodegenerative diseases.
Learn More Dage Lab

Kareken Lab

The Kareken Lab uses neuroimaging to understand the human brain’s reward system in studies of alcoholism and obesity.
Learn More Kareken Lab

Obeid Lab

The Obeid lab studies the mechanisms of seizures and the accompanying cognitive and behavioral deficits using electrophysiological, behavioral and molecular techniques.
Learn More Obeid Lab
research image under microscope

Wilcock Lab

The Wilcock lab was established in 2011 with a focus on vascular contributions to cognitive impairment and dementia (VCID) and neuroinflammation in VCID and Alzheimer’s disease.
Learn More Wilcock Lab

Liana G. Apostolova, MD, MS

Associate Dean of Alzheimer's Disease Research

Jared R. Brosch, MD

Associate Professor of Clinical Neurology

David G. Clark, MD

Associate Professor of Clinical Neurology

Jeff Dage, PhD

Senior Research Professor of Neurology

Yansheng Du, PhD

Professor of Neurology

Mario Dzemidzic, PhD

Associate Research Professor of Neurology

Huiying Gu, M.D.

Assistant Research Professor of Neurology

Dustin Hammers, PhD

Associate Professor of Neurology

Naazneen Khan, PhD

Assistant Research Professor of Neurology

Ann E. Kosobud, PhD

Associate Scientist in Neurology

Makram Obeid, MD

Assistant Professor of Neurology

Erica M. Weekman, PhD

Assistant Research Professor of Neurology

Donna M. Wilcock, PhD

Barbara and Larry Sharpf Professor of Alzheimer's Disease Research

Meichen Yu, PhD

Assistant Professor of Radiology & Imaging Sciences