Neuropsychology Alcohol Studies Lab

The Kareken Lab, led by David A. Kareken, PhD, uses neuroimaging to understand the human brain’s reward system in studies of alcoholism and obesity. The alcohol research conducted in this laboratory is funded by the National Institute of Alcohol Abuse and Alcoholism.

Participate in a Study

The Kareken lab is seeking participants who drink alcohol and are between the ages of 21 and 30. Compensation for lab studies range between $325 and $575. Interested candidates are encouraged to sign up to participate in a Kareken lab study. Additionally, applicants can create a volunteer profile with All IN for Health to learn more about health research opportunities throughout the state.

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fMRI Study of Taste and Alcohol Use

This study takes place over two days. On the first day, participants undergo an MRI while tasting both still and sweetened water. On a separate day, participants are able to give themselves alcohol as delivered intravenously through a vein in the arm. The study and prerequisite in-person screening take place in Indianapolis at Goodman Hall and University Hospital and are conducted Monday through Friday. Participants in this study receive up to $325 and have the opportunity for additional payment during the study visit.

PET Study of Alcohol

In addition to an in-person screening, this study requires an overnight stay at University Hospital’s Clinical Research Center in Indianapolis. On the first day, subjects briefly experience intravenously administered alcohol and have two PET scans at Goodman Hall while they perform a task. Depending on task performance, subjects may then have the opportunity to give themselves intravenous alcohol following the PET scans. Subjects then spend the night at University Hospital and are discharged at 7 am the following day. This study is conducted primarily on Tuesdays, Wednesdays and Thursdays. Participants in this study receive up to $575 and have the opportunity for additional payment during the study visit.

Faculty Research Team

David A. Kareken, PhD

Professor of Neurology

Mario Dzemidzic, PhD

Associate Research Professor of Neurology

Additional Research Team Members

Other research team members include Sarine Janetsian-Fritz, PhD; Shreya Patel; MaKayla Picklesimer; and Yitong Shen.