The Indiana Spinal Cord and Brain Injury Research Group (ISCBIRG) at Indiana University School of Medicine is an integrated component of Stark Neurosciences Research Institute. The group, led by Xiao-Ming Xu, PhD, is comprised of a crital mass of key principal investigators who study molecular mechanisms underlying spinal cord injury (SCI) and traumatic brain injury (TBI) and develop novel repair strategies to promote neural reorganization and functional recovery in experimental models of these injuries. The long-term goal of these studies is to translate promising treatments from animal models to humans. Additionally, several faculty conduct behavioral, pharmacological and neuroimaging research in human pediatric, adolescent and adult TBI.