The Electrophysiology Core performs rodent brain slice recordings. Examples of recordings include measures of synaptic transmission, long-term plasticity, cellular excitability, and testing pharmacological responses. The Core is capable of utilizing optogenetic and chemogenetic tools. Electrophysiological assessments of brain function in rodent models is a specialty of the Core. Services include data collection, data analysis, and write up of results if requested.
Request Services
In need of services at the Electrophysiology Core? Submit this request form. IU employees can access more information about the core on the SNRI Intranet.
What can the Core do for you?
- Assess how a genetic mutation affects action potential firing or synaptic plasticity such as long-term potentiation.
- Perform concentration-response assessments of drug treatments.
- Validate that an in vivo manipulation produces a neurobiological effect at the cellular level.
- Identify physiological mechanisms that underlie measured behaviors.
- Determine the functional consequences of biochemical or anatomical changes measured at synapses, neurons, and/or glia.
- Assess cell type-specific mechanisms or consequences of a treatment.
- Determine how manipulations of one cell type affect other nearby cell types and neuronal population responses.
Available Services
- Synaptic plasticity
- Synaptic strength
- Neuronal excitability
- Drug effects
- Optogenetics
- Chemogenetics
Core Leadership
