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Services

The Center for Medical Genomics at Indiana University School of Medicine offers state-of-the-art genomic technology and staff expertise to investigators conducting biomedical research. The center is equipped with a variety of advanced genomics instrumentation and offers services at all stages of the experiment.

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Please contact the Center for Medical Genomics program manager for a service quote or to schedule a consultation.

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  • DNA/RNA Analysis

    The Center for Medical Genomics offers DNA/RNA quantification, DNA quality control and fragment-size analysis, RNA quality (measure of fragmentation/degradation), and miRNA quality. DNA/RNA Analysis services include quality/quantity assessment as well as shearing and sample extraction. Instruments include NanoDrop, Agilent 2100 Bioanalyzer, Qubit Fluorometer, and Covaris S2 Focused-ultrasonicator.

  • Single Cell Analysis
    Single cell analysis includes single cell RNA-seq, single nucleus RNA-seq, single cell ATAC-seq, single cell copy number variation (CNV) and single cell immune profiling. The center is equipped with three 10x Genomics Chromium Systems. Investigators are responsible for preparing high-quality single-cell suspension from biological specimens. FAQs about single cell studies give additional details about this service.
  • DNA Sequencing 

    The Center for Medical Genomics offers whole genome sequencing, whole exome sequencing, gene panel target sequencing, 10x LinkedRead sequencing and ChIP-seq.

  • RNA Sequencing

    RNA sequencing services include whole transcriptome sequencing, mRNA sequencing, and miRNA sequencing. FAQs about RNA-sequencing give additional details about this service.

  • Metagenomics

    Metagenomics services include 16S sequencing and shotgun sequencing.

  • High-throughput Genotyping

    The Center for Medical Genomics offers high-throughput targeted genotyping using single-nucleotide polymorphism (SNP), allele-specific expression and validation of methylation sites. The center uses the Sequenom MassArray® system for targeted genotyping, generally in groups of up to 25 or 30 SNPs per assay and can be used to genotype SNPs in any organism.