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Supporting your musculoskeletal health research

The Clinical Research Center serves as the cornerstone for human subjects research conducted in the Indiana Center for Musculoskeletal Health and receives funding through a P30 grant from NIH NIAMS. This team is working to better define musculoskeletal diseases that have common pathogenesis and clinical presentations.

With the exemplary team of investigators, the core has integrated a network of electronic health records and molecular profiles to identify genetic factors, clinical and biochemical phenotypes, and to standardize physical function measurements and imaging modalities to define the diseases’ functional and morphologic phenotypes. Improving the definition and diagnosis of these musculoskeletal conditions could lead to personalized medicine advances, enabling health care providers to prescribe tailored treatment for each patient.

org chart of the clinical research cores. At the top, the cores are led by Sharon Moe and Michael Econs. Internal and external steering committees give guidance to the cores. Under that, the Administrative Core is over the Methodology Core and Resource (FIT) Core. Under methodology, there are groups for statistics, computational services, regenstrief data service core, and data navigator. Under the Resource (FIT) Core, there are groups for the biobank and FIT core coordinators.
Explore the Cores
medical illustration of the human spine and integrated muscles

Function, Imaging and Tissue Resource Core 

The Function, Imaging and Tissue (FIT) Resource Core offers standardized imaging outcomes for bone and muscle health assessments and a standardized data entry platform for physical function outcomes and training in the performance and interpretation of these outcomes. Specimens and tissues related to musculoskeletal health are available through the Indiana Biobank.

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Big Data, Informatics and Omics Core

The Big Data, Informatics and Omics Core contains the Computable Phenotype Research Core and the Clinical Trial Design and Omic Service Core. This group connects investigators and facilitates multi-disciplinary research that leverages the use of novel technologies and resources to improve musculoskeletal health.

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three members of the administrative core team wearing lab coats

Administrative Core

The administrative core facilitates cross-disciplinary research by working with the Indiana Center for Musculoskeletal Health researchers. This core also enhances internal and external communications, provides pilot funding, trains the next generation of musculoskeletal researchers, and provides oversight and evaluation of the other clinical research cores.

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