CPT Code(s): 88230, 88261, 88280, 88289
Service Code (IU Health): 53100293, 53100566, 53100715, 53100772
Ordering Recommendation: Detection of numerical and structural abnormalities of autosomes and sex chromosomes. G-banded karyotyping allows for the visualization and analysis of chromosomes for chromosomal rearrangements, including genomic gains and losses. Post-natal peripheral blood (leukocyte) chromosomes are indicated for an array of physical and/or mental difficulties. Approximately 7/1,000 live-births each year have a chromosome abnormality. Chromosomal microarray (CMA) is recommended if congenital anomalies are present that are not well defined by a known syndrome. CMA is also recommended for developmental delay and autism spectrum disorders. Companion fluorescence in-situ hybridization (FISH) testing may also be utilized.
Synonyms: Karyotype, G-bands, Constitutional, Congenital, Klinefelter Syndrome, Turner Syndrome, XYY Syndrome, Trisomy X, Triple X Syndrome, XXX, XXY, XYY, XXYY, XO
Methodology: Tissue culture, high resolution microscopic analysis of G-banded chromosomes. If ordered, fluorescence in-situ hybridization (FISH) analysis of metaphase cells.
Performed: Monday through Saturday
Reported: 7-10 days