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About the Biochemical Genetics Laboratory

The Biochemical Genetics Laboratory was founded in 2017 under the direction of Marcus J. Miller, PhD, FACMG. The lab is a division of the Indiana University School of Medicine Genetic Testing Laboratories in Indianapolis, IN.

The mission of the Biochemical Genetics Lab is to provide core biochemical genetics testing services to IU Health and surrounding hospitals. Enabled by state-of-the-art liquid chromatography tandem mass spectrometry equipment, the lab has created a number of novel laboratory developed tests that provide unique advantages in terms of expanded clinical utility through the addition of atypical analytes, ultra low-specimen volume requirements, and rapid analysis times. We specialize in small molecule metabolite analyses (e.g., amino acids, acylcarnitines and organic acids). Many of our tests contain unique combinations of analytes that would require multiple individual tests if ordered elsewhere. Our test menu has broad applications beyond clinical diagnostics—a secondary focus of our lab is to provide high quality targeted metabolomics testing to the research community.

Work with the Biochemical Genetics Laboratory

The Biochemical Genetics Laboratory is actively looking for clinical and research partners.

2 Average test turn around time (days) in 2020
81 Human metabolites quantified by our tests
0.1 Volume (mL) of sample needed for most tests

Quality Assurance

The Biochemical Genetics Laboratory is accredited by the College of American Pathologists (CAP), certified by CLIA, and holds state specific licensure for numerous states. To ensure the quality of our testing, we participate in multiple different proficiency testing schemes including: CAP Chemistry/Therapeutic Drug Monitoring, CAP Biochemical Genetics, and European Research Network for evaluation and improvement of screening, Diagnosis and treatment of Inherited disorders of Metabolism (ERNDIM). Our performance in these schemes demonstrates the high quality of our testing.
38384-Miller, Marcus

Marcus J. Miller, PhD

Associate Professor of Clinical Medical & Molecular Genetics

Director, Biochemical Genetics Laboratory

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2831-Vance, Gail

Gail H. Vance, MD

Sutphin Professor Emeritus of Cancer Genetics

Director, IU Genetic Testing Laboratories

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