PGX Warfarin Genotyping

CPT Code(s): 81227, 81355, 81479

Service Code (IU Health): 53102208, 53102216

Ordering Recommendation: Information about genotype may be used as an aid to clinicians in determining therapeutic strategy and treatment dose for warfarin.

Synonyms: CYP2C9, VKORC1, CYP4F2, warfarin, Coumadin®

Methodology: Realtime polymerase chain reaction (PCR) and microarray analysis

Performed: Weekly

Reported: 7-10 days

Collect: Preferred: Lavender (EDTA); Acceptable: Yellow (ACD Solution A or B), Green (Heparin), Saliva (Oragene collection device)

Specimen Volume: Blood: 3 mL whole blood (minimum 1 mL); Saliva: 2 mL

Storage/Transport: Refrigerated/Room temperature

Unacceptable Conditions: Grossly hemolyzed or clotted

Stability: One month refrigerated; One month frozen