PGX IL28B (IFNL3) Genotyping

CPT Code(s): 81400

Service Code (IU Health): 53102265

Ordering Recommendation: Information about genotype may be used as an aid to clinicians in determining therapeutic strategy and treatment dose for PEG-interferon-alpha.

Synonyms: IL28B, IFNL3, pegylated interferon

Methodology: Realtime polymerase chain reaction (PCR) and microarray analysis

Performed: Weekly

Reported: 7-10 days

Collect: Preferred: Lavender (EDTA); Acceptable: Yellow (ACD Solution A or B), Green (Heparin), Saliva (Oragene collection device)

Specimen Volume: Blood: 3 mL whole blood (minimum 1 mL); Saliva: 2 mL

Storage/Transport: Refrigerated/Room temperature

Unacceptable Conditions: Grossly hemolyzed or clotted

Stability: One month refrigerated; One month frozen