PGX Pharmacogenomics Genotyping Panel

CPT Code(s): 81225, 81226, 81227, 81230, 81231, 81232, 81247, 81306, 81328, 81335, 81355, 81479

Ordering Recommendation: Information about genotype may be used as an aid to clinicians in determining therapeutic strategy for individuals.

Synonyms: CYP2D6, TPMT, NUDT15, CYP2C19, SLCO1B1, VKORC1, CYP2C9, CYP3A4, CYP3A5, CYP2B6, DPYD, CYP4F2, G6PD, CYP2C cluster

Methodology: Real-time polymerase chain reaction (PCR) and hydrolysis probe analysis. Copy number for CYP2D6 was performed using the delta delta Ct method.

Performed: Weekly

Reported: 7-10 days

Collect: Preferred: Lavender (EDTA); Acceptable: Yellow (ACD Solution A or B), Green (Heparin), Saliva (Oragene collection device)

Specimen Volume: Blood: 3 mL whole blood (minimum 1 mL); Saliva: 2 mL

Storage/Transport: Refrigerated/Room temperature

Unacceptable Conditions: Grossly hemolyzed or clotted

Stability: One month refrigerated; One month frozen