Kidney Transplant Recipient, African American Genotyping Panel

CPT Code(s): 81226 (CYP2D6), 81230 (CYP3A4), 81231 (CYP3A5), 81479 (APOL1)

Service Code (IU Health): 8184626715

Ordering Recommendation: Information about genotype may be used as an aid to clinicians in determining therapeutic strategy for individuals undergoing kidney transplant.

Synonyms: CYP2D6, CYP3A4, CYP3A5, APOL1, kidney transplant, tacrolimus, pain, opioids

Methodology: Real-time polymerase chain reaction (PCR) and hydrolysis probe analysis

Performed: Weekly

Reported: 7-10 days

Collect: Preferred: Lavender (EDTA); Acceptable: Yellow (ACD Solution A or B), Green (Heparin), Saliva (Oragene collection device)

Specimen Volume: Blood: 3 mL whole blood (minimum 1 mL); Saliva: 2 mL

Storage/Transport: Refrigerated/Room temperature

Unacceptable Conditions: Grossly hemolyzed or clotted

Stability: One month refrigerated; One month frozen