Showing results for Alzheimer's disease

Alzheimer’s researchers study drug efficacy in early stages of disease

Most drugs developed to treat Alzheimer’s disease have for years been ineffective in clinical trials. Researchers from Indiana University School of Medicine recently evaluated the efficacy of a failed clinical trial drug using their rigorous pipeline.

IU School of Medicine | Jul 25, 2022

IU School of Medicine-Evansville faculty receives grant to lead new study on Alzheimer’s disease

An Indiana University School of Medicine-Evansville faculty member has received a grant from the Alzheimer’s Association for new research to enhance detection of cortical atrophy in patients diagnosed with Alzheimer's disease.

IU School of Medicine | Jun 28, 2022

a close up photo of an elderly couple's clasped hands

IU physicians, researchers using new screening tools for early detection of Alzheimer’s

Some patients in Indiana are now able to receive new screenings for early detection of Alzheimer’s disease thanks to a pilot program at Indiana University School of Medicine and Indiana University Health.

Christina Griffiths | Jun 01, 2022

Alzheimer’s disease blood test research at IU continues to advance the field with a community-based study

An Indiana University School of Medicine researcher is gaining ground on the development of novel, cutting-edge blood tests to aid in the diagnosis and treatment of Alzheimer’s disease.

IU School of Medicine | May 31, 2022

Researchers investigate connection between loss of motivation and Alzheimer’s disease progression

Researchers are studying why neuropsychiatric symptoms, such as apathy and irritability, appear in most Alzheimer’s disease patients before the onset of memory loss.

IU School of Medicine | Apr 25, 2022

Researchers discover new information about amyloid filaments in neurodegenerative diseases

Experts at Indiana University School of Medicine have helped identify that a common protein found in neurodegenerative diseases forms amyloid filaments in an age-dependent manner without a connection to disease.

IU School of Medicine | Mar 28, 2022

New study shows pathological differences in inherited versus sporadic Alzheimer's disease

Indiana University School of Medicine researchers are making new discoveries about the pathological changes in people who have inherited Alzheimer’s disease versus developing the disease sporadically. These findings could lead to new ways of preventing and treating the disease.

Christina Griffiths | Jan 18, 2022

Alzheimer’s disease research programs at IU School of Medicine collaborate on disease models, drug discovery of gene

Investigators from two of Indiana University School of Medicine’s largest funded research programs are collaborating on a study investigating the biology behind a gene associated with Alzheimer’s disease, with the hopes of developing a drug to treat the disease.

IU School of Medicine | Nov 09, 2021

Researchers investigate role of gene associated with Alzheimer’s disease in brain’s immune cells

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them. Researchers at Indiana University School of Medicine have been investigating how these immune cells in the brain—microglia—relate to a gene mutation recently found in Alzheimer’s disease patients.

IU School of Medicine | Nov 03, 2021

IU researcher member of expert panel on Alzheimer's disease drug

When the Food and Drug Administration approved the use of the drug aducanumab to treat Alzheimer’s disease in early June, leaders in neurodegeneration research quickly created an expert panel to issue guidance to physicians on how to best administer the drug.

IU School of Medicine | Sep 08, 2021