Showing results for Alzheimer's disease

Protein found in brain linked to frontotemporal dementia

An international team of researchers including experts at the Indiana University School of Medicine has identified a protein found in the brains of people with frontotemporal dementia (FTD), discovering a new target for potential treatments for the disease.

IU School of Medicine | Dec 07, 2023

IU researchers develop new brain network modeling tools to advance Alzheimer's disease research

Indiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously developed to analyze brains of patients in the clinic—to investigate Alzheimer’s disease progression in preclinical animal models.

IU School of Medicine | Nov 30, 2023

A researcher works in a IU School of Medicine biomarker lab.

IU scientists part of NIH-funded national consortium focused on improving Alzheimer’s disease diagnoses

Researchers at Indiana University School of Medicine will play key roles in a national consortium led by Wake Forest University School of Medicine to study the use, interpretation and implementation of biomarkers to diagnose Alzheimer’s disease.

IU School of Medicine | Oct 27, 2023

a close up photo of gloved hands preparing a sample in the lab

IU researchers identify new gene mutation that alters Alzheimer’s disease risk

A groundbreaking study led by experts from Indiana University School of Medicine has shed new light on the genetic underpinnings of Alzheimer's disease.

IU School of Medicine | Sep 06, 2023

close up photo of a person's hand being held in support by a caregiver

Statewide project to provide care and support to people living with dementia and their care partners

An Indiana University School of Medicine statewide project in collaboration with Indiana University Health was recently funded to support people living with dementia as well as their family care partners find more support and resources, thanks to a new $686,000 grant from the National Institute on Aging IMPACT Collaboratory.

IU School of Medicine | Aug 29, 2023

Tau protein in Alzheimer's disease, illustration. The insets show two ways in which pathological phosphorylation (yellow) of Tau proteins (red-orange) by kinases (blue-purple) affect nerve cells in what is called a neurofibrillary tangle. The main illustration showing a nerve cell (neuron, blue, lower left) and its axon (across bottom), shown in a misshapen and abnormal state. Pathological aggregations of tau proteins cause disintegration of microtubules (inset at left). The transport of synaptic vesicles (orange-blue spheres, inset at right) is also interrupted. A neurofibrillary tangle consists of abnormal aggregates and insoluble fibres of the protein tau. Tau protein is an abundant neural protein, aggregations of which are thought to play a role in Alzheimer's disease and other neural disorders.

Neuroscientists create new resource to improve Alzheimer’s disease research models

Genetic diversity key to new study on abnormal protein accumulation in the brain—a hallmark of Alzheimer’s disease development

IU School of Medicine | Aug 22, 2023

Cristian Lasagna-Reeves, PhD presents at AAIC 2023.

IU School of Medicine researchers share expertise at international Alzheimer’s disease conference

Researchers from Indiana University School of Medicine will have a large presence and leadership role at the upcoming Alzheimer’s Association International Conference 2023 in Amsterdam, Netherlands, with involvement in more than 150 presentations at the four-day meeting.

IU School of Medicine | Jul 17, 2023

IU School of Medicine names Apostolova associate dean for Alzheimer’s disease research

Liana G. Apostolova, MS, MD, FAAN, has been named associate dean for Alzheimer’s disease research at Indiana University School of Medicine. The role is a newly established leadership position on the research cabinet of Tatiana Foroud, PhD, executive associate dean for research affairs at the school.

IU School of Medicine | May 11, 2023

IU neuroscientists lead new study laying groundwork for Alzheimer’s disease precision medicine

Researchers at Indiana University School of Medicine are co-leading a 5-year, $41 million study to better understand the biological pathways underlying Alzheimer’s disease and ultimately create more personalized patient care.

IU School of Medicine | Mar 28, 2023

Alzheimer’s disease researchers study gene associated with the brain’s immune cells

Indiana University School of Medicine researchers are studying how the reduction of a gene variant found in the brain’s immune cells could diminish the risk of late-onset Alzheimer’s disease.

IU School of Medicine | Jan 05, 2023