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IU School of Medicine findings set new standard for use of blood-based biomarkers in clinical trials for prediction of cancer recurrence

Indiana University School of Medicine researchers Milan Radovich, PhD, and Bryan Schneider, MD, have discovered that the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in the plasma of women’s blood who have undergone chemotherapy prior to surgery for the treatment of stage 1, 2 or 3 triple negative breast cancer are critical indicators for the prediction of disease recurrence and disease-free survival.

IU School of Medicine  |  Jul 09, 2020

IU cancer researcher earns $1.6 million NCI grant for multiple myeloma bone disease therapies

An IU Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $1.6 million grant from the National Cancer Institute to study ways to build bone and decrease tumor growth in multiple myeloma bone disease.

IU School of Medicine  |  May 11, 2020

Cancer center researchers identify checkpoint target for colorectal cancer immunotherapy

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a target for colorectal cancer immunotherapy.

IU School of Medicine  |  May 07, 2020

Researchers develop publication with collaborator quarantined in China during COVID-19 outbreak

IU School of Medicine scientists published research in Nature Communications this week, overcoming significant obstacles of the current COVID-19 pandemic.

IU School of Medicine  |  Apr 15, 2020

IU cancer researcher identifies new areas in human genomes linked to skin cancer risk

INDIANAPOLIS — An Indiana University cancer researcher has identified eight new genomic regions that increase a person’s risk for skin cancer. Jiali Han, Ph.D., and colleagues discovered eight new loci—locations on a person’s genome—that are susceptible to the development of squamous cell skin cancer. Han is the Rachel Cecile Efroymson Professor in Cancer Research at […]

Michael Schug  |  Feb 18, 2020

IU Simon Cancer Center researchers receive $3 million in NIH grants to investigate cell functions within bone marrow

INDIANAPOLIS — More than $3 million from the National Institutes of Health will allow Indiana University Melvin and Bren Simon Cancer Center researchers to improve understanding of the complex system of how hematopoietic stem cells (HSC) survive and sustain their function in the bone marrow. Edward F. Srour, Ph.D., the Robert J. and Annie S. […]

IU School of Medicine  |  Jan 30, 2020

IU School of Medicine hosting “Us vs. HPV” webinars for HPV Prevention Week

The Indiana University School of Medicine National Center of Excellence in Women’s Health is getting ready for a week of raising awareness about human papilloma virus (HPV). “We have to protect our community,” said Theresa Rohr-Kirchgraber, MD, FACP, FAMWA, executive director of the National Center of Excellence. “We have to protect our children, and we […]

Christina Griffiths  |  Jan 21, 2020

Indiana University School of Medicine researchers discover emerging combination therapy that halts tumor growth based on Tyler Trent’s cell lines

INDIANAPOLIS – Researchers at Indiana University School of Medicine have found a combination therapy that significantly slows tumor growth in models, built from cells taken from Tyler Trent’s tumors. Tyler was a Purdue University student and football superfan who died on January 1, 2019, after waging a long and valiant fight against an aggressive form […]

IU School of Medicine  |  Jan 16, 2020

IU School of Medicine researchers predict which triple negative breast cancer patients may avoid recurrence and those who are at high-risk of relapse

SAN ANTONIO — Indiana University School of Medicine researchers have discovered how to predict whether triple negative breast cancer will recur, and which women are likely to remain disease-free. They will present their findings on December 13, 2019, at the San Antonio Breast Cancer Symposium, the most influential gathering of breast cancer researchers and physicians in the world.   Milan Radovich, PhD, and Bryan Schneider, […]

IU School of Medicine  |  Dec 13, 2019

Trial seeks to reduce neuropathy, improve outcomes for black women with breast cancer

Researchers at Indiana University School of Medicine have launched a new, unique study recruiting black women with breast cancer designed to better understand and treat neuropathy, a side effect from chemotherapy. The National Cancer Institute-sponsored clinical trial, EAZ171, is led by Bryan P. Schneider, MD, professor of medicine and medical and molecular genetics and the […]

IU School of Medicine  |  Sep 05, 2019