Researchers at Indiana University School of Medicine are learning more about how a person’s genes play a role in the possibility they’ll suffer from alcoholic cirrhosis with the discovery of a gene that could make the disease less likely.
A study conducted by Indiana University School of Medicine researchers has shown that asymptomatic COVID-19 infection is possible in children younger than 10 years old. The researchers have shared the results of their novel COVID-19 study of asymptomatic children and adults in Marion County known as TACTIC (Tracking Asymptomatic COVID-19 Through Indianapolis Communities).
Researchers at Indiana University School of Medicine have discovered new information about how a dangerous parasite takes control of a patient’s cells as it spreads throughout their body, an important finding that could help in the development of new drugs to treat this infection.
Indiana University School of Medicine researchers Milan Radovich, PhD, and Bryan Schneider, MD, have discovered that the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in the plasma of women’s blood who have undergone chemotherapy prior to surgery for the treatment of stage 1, 2 or 3 triple negative breast cancer are critical indicators for the prediction of disease recurrence and disease-free survival.
A team of international researchers has learned that dose escalation of hydroxyurea treatment for children in Uganda with sickle cell anemia is more effective and has similar side effects than a lower fixed dose of the same drug. The study, known as NOHARM MTD (Novel use Of Hydroxyurea in an African Region with Malaria – Maximum Tolerated Dose), focused on children in Uganda, but the results could impact use of hydroxyurea worldwide, including the United States and Europe. The findings are being published in the June 25 issue of the New England Journal of Medicine.
INDIANAPOLIS — More than 3 million Americans have glaucoma, a serious eye condition causing vision loss. Using human stem cell models, researchers at Indiana University School of Medicine found they could analyze deficits within cells damaged by glaucoma, with the potential to use this information to develop new strategies to slow the disease process.
Building on years of groundbreaking discoveries in stem cell research, scientists from Indiana University School of Medicine and Harvard Medical School have determined how to grow hairy skin using human stem cells—developing one of the most complex skin models in the world. The study, published June 3 in Nature, shows that skin generated from pluripotent stem cells can be successfully grafted on a nude mouse to grow human skin and hair follicles. That discovery could lead to future studies in skin reconstruction, disease modeling and treatment.
As COVID-19 continues its sweep around the globe, dialysis units have continued to be hotspots for the virus’ spread. Researchers at Indiana University School of Medicine hope to combat that threat, through a novel study published May 14, 2020 in JAMA.