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Showing results for Research Findings

Blood test predicts psychosis risk, most effective treatments

A team of researchers led by Indiana University School of Medicine faculty have developed a breakthrough new blood test for schizophrenia, a psychiatric disorder that includes hallucinations and delusions.

IU School of Medicine  |  Feb 08, 2024

Protein found in brain linked to frontotemporal dementia

An international team of researchers including experts at the Indiana University School of Medicine has identified a protein found in the brains of people with frontotemporal dementia (FTD), discovering a new target for potential treatments for the disease.

IU School of Medicine  |  Dec 07, 2023

Researchers reveal uncharted liver-focused pathway in gene therapy immune responses

Indiana University School of Medicine researchers have uncovered vital insights regarding a liver trigger that blocks an undesired immune response from gene therapy, surprisingly resulting in the activation of specific immune cells, despite the liver's typical role in suppressing immune responses. The findings, published in Molecular Therapy, may pave the way for change in immunomodulation strategies for desired and long-lasting effects of gene therapy.

IU School of Medicine  |  Dec 07, 2023

IU researchers develop new brain network modeling tools to advance Alzheimer's disease research

Indiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously developed to analyze brains of patients in the clinic—to investigate Alzheimer’s disease progression in preclinical animal models.

IU School of Medicine  |  Nov 30, 2023

New target identified for pulmonary hypertension treatment

Indiana University School of Medicine researchers at the school’s South Bend regional campus, in collaboration with colleagues at the University of Notre Dame, have identified a new therapeutic target for pulmonary hypertension, a type of high blood pressure that affects the blood vessels in the lungs. Their findings were recently published in Circulation Research.

IU School of Medicine  |  Nov 17, 2023

Repurposed drug offers new potential for managing type 1 diabetes

A recent study led by Indiana University School of Medicine in collaboration with the University of Chicago Medicine presents exciting future possibilities for the management of type 1 diabetes and the potential reduction of insulin dependency.

IU School of Medicine  |  Nov 01, 2023

First ever clinical classification of heart attacks based on tissue damage adopted by Canadian Cardiovascular Society

The Canadian Cardiovascular Society (CCS) released the world’s first classification of acute myocardial infarction (AMI) — or heart attack — based on heart tissue damage research that was driven by two cardiovascular investigators within the Ischemic Heart Disease Program of Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine and Northern Ontario School of Medicine.

IU School of Medicine  |  Oct 29, 2023

Specific gut bacteria increase risk of severe malaria

Indiana University School of Medicine researchers have identified multiple species of bacteria that, when present in the gut, are linked to an increased risk of developing severe malaria in humans and mice.

IU School of Medicine  |  Oct 27, 2023

IU cancer center researchers identify biology behind aggressive breast cancers in Black women

Researchers at Indiana University Melvin and Bren Simon Comprehensive Cancer Center are unlocking the biology behind aggressive breast cancers in Black women.

IU Simon Comprehensive Cancer Center  |  Oct 25, 2023

IU researchers identify new gene mutation that alters Alzheimer’s disease risk

A groundbreaking study led by experts from Indiana University School of Medicine has shed new light on the genetic underpinnings of Alzheimer's disease.

IU School of Medicine  |  Sep 06, 2023