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Showing results for Global health

IU School of Medicine selected for COVID-19 vaccine clinical trial

As researchers around the world work feverishly to discover a vaccine in the battle to prevent COVID-19, Indiana University School of Medicine has been selected as a site for a vaccine trial. Biopharmaceutical company AstraZeneca, in partnership with Oxford University, is moving forward with its late-stage clinical trial for a vaccine known as AZD1222

IU School of Medicine  |  Sep 03, 2020

Researchers discover improved treatment for children with sickle cell anemia

A team of international researchers has learned that dose escalation of hydroxyurea treatment for children in Uganda with sickle cell anemia is more effective and has similar side effects than a lower fixed dose of the same drug. The study, known as NOHARM MTD (Novel use Of Hydroxyurea in an African Region with Malaria – Maximum Tolerated Dose), focused on children in Uganda, but the results could impact use of hydroxyurea worldwide, including the United States and Europe. The findings are being published in the June 25 issue of the New England Journal of Medicine. 

IU School of Medicine  |  Jun 25, 2020

IU School of Medicine’s new global health leader draws from extensive experience in Kenya

INDIANAPOLIS — Adrian Gardner, MD, MPH, a global health leader who spent the last seven years in Kenya as part of the Indiana University School of Medicine-led AMPATH program, has been named the school’s associate dean for global health. He will also serve as director of the IU Center for Global Health, an umbrella institute […]

Karen Spataro  |  Jan 24, 2020

Scientists link behavioral problems to malaria-related kidney injury

Earlier this year, researchers determined that a common complication for children recovering from severe malaria is linked to long-term cognitive impairment. Now, they’ve worked to define how those impairments translate to behavioral outcomes for the thousands of children affected—especially in sub-Saharan Africa, where they are at high risk for parasite exposure. In a study published […]

IU School of Medicine  |  Dec 17, 2019

Brain injury marker linked to long-term impairment in children with malaria

Malaria continues to be a major threat to public health for much of the world’s population. In 2017, more than 400,000 malaria-related deaths were reported globally, and over 90 percent were in sub-Saharan Africa. Almost two-thirds of the deaths were in children. The most severe and deadliest form of the parasitic disease is cerebral malaria, […]

IU School of Medicine  |  Jun 04, 2019

Study finds link between kidney injury, neurocognitive impairment in children with malaria

More than 200 million children around the world are at risk of failing to meet their developmental potential, and the risk is highest for children in sub-Saharan Africa. In that part of the world, severe malaria is a leading cause of acquired neurodisability—leaving many children with developmental delay even years after recovery. Scientists don’t fully […]

IU School of Medicine  |  May 21, 2019

Medical students to experience health care in Kenya

Hands-on global health opportunities and challenges await four first-year IU School of Medicine students selected to travel to the AMPATH program in western Kenya this summer. Students Sean Buehler, Michael Harding, Bilal Jawed and Grace Rushton form this year’s class of student ambassadors, called Slemenda Scholars, who will learn about every facet of AMPATH’s programs […]

IU School of Medicine  |  Mar 13, 2019

Braters to chair IU Center for Global Health development board

During more than a dozen visits over the last 24 years, Stephanie and Craig Brater have witnessed the transformative development of the health care system in western Kenya and that experience will fuel more global health advances as they assume leadership of the Indiana University Center for Global Health development board. Established in 2010, the […]

IU School of Medicine  |  Mar 11, 2019

IU researchers identify way to block malaria-causing parasites’ ability to shield themselves against popular drug treatment

Indiana University School of Medicine researchers have identified a way to block the ability of parasites that cause malaria to shield themselves against drug treatments in infected mice—a finding that could lead to the development of new approaches to combat this deadly disease in humans.

IU School of Medicine  |  Dec 13, 2017

Study: Sickle cell anemia treatment does not increase malaria risk in Africa

The drug hydroxyurea does not appear to increase the risk of malaria infection in patients with sickle cell anemia who live in malaria-endemic regions, according to a study published online today in Blood, a Journal of the American Society of Hematology (ASH).

IU School of Medicine  |  Oct 19, 2017