Faculty Labs

Successful biomedical research demands collaboration among scientists with varying specialties. Faculty throughout IU School of Medicine's 25 academic departments work together to advance knowledge and treatment for patients in the world's most critical areas of medicine.

Allen Lab

The Allen Laboratory (Indianapolis) is studying the tissue-level mechanisms responsible for musculoskeletal integrity in health and disease by utilizing numerous in vivo model systems that help investigators understand how disease and pharmaceutical intervention influence bone structure, cellular activity, tissue-level properties, and biomechanical properties.

Principal Investigator Matthew R. Allen, PhD

Phone (317) 274-1283

Clauss Lab

The research lab (Indianapolis) of Matthias Clauss, PhD, is focused on vascular function and repair are involved in many diseases, in particular in those of the cardiopulmonary system.

Principal Investigator Matthias A. Clauss, PhD

Phone

Conway Lab

The Conway Lab (Indianapolis) is located in the Herman B Wells Center for Pediatric Research and focuses on the examination and manipulation of the molecular regulatory mechanisms that govern cardiopulmonary development and disease.

Principal Investigator Simon J. Conway, PhD

Phone (317) 278-8780

Cornetta Lab

The Cornetta Lab (Indianapolis) is using viral-based gene transfer as a means of introducing genetic sequences to correct mutations and ameliorate disease.

Principal Investigator Kenneth G. Cornetta, MD

Phone

Dent Lab

The Dent Laboratory (Indianapolis) is focused on the regulation of the immune response by CD4 T helper and regulatory T cells.

Principal Investigator Alexander L. Dent, PhD

Phone (317) 274-7524

Field Lab

The Field Lab (Indianapolis) focuses on regenerative growth of the heart. The lab works to develop strategies to monitor the intrinsic rates of cardiomyocyte cell cycle renewal in normal and injured adult hearts, as well as strategies to induce regenerative growth following myocardial injury.

Principal Investigator Loren J. Field, PhD

Phone

Han Lab

The long-term goal of the research in the laboratory of Renzhi Han, PhD, (Indianapolis) is to shed light on the molecular mechanisms underlying muscular dystrophy, cardiomyopathy and dyslipidemia-associated cardiovascular diseases, and to develop adeno-associated viral (AAV) based gene replacement and gene editing therapies for these genetic and metabolic diseases.

Principal Investigator Renzhi Han, PhD

Phone (317) 274-5642

Kim Lab

The Kim Lab (Indianapolis) investigates genetic regulation and signaling pathways in cardiac disease using state-of-the-art cell approaches and mouse model systems. The lab is particularly interested in transcriptional regulation and noncoding RNA regulatory network by seven-transmembrane receptor (also known as G protein-coupled receptor)-mediated signaling pathways in heart failure.

Principal Investigator Il-Man Kim, PhD

Phone 317-278-2086

Kline Lab

The Kline Lab (Indianapolis) focuses on venous thromboembolism, and his lab conducts clinical and applied laboratory research intended to improve the therapeutic index of all steps of venous thromboembolism diagnosis and treatment.

Principal Investigator Jeffrey A. Kline, MD

Phone (317) 880-3869

Lai Lab

The Lai Lab (Indianapolis) investigates pathogenesis and development of alternative therapies for effective treatment of cardiopulmonary diseases, with the particular emphasis of metabolic syndrome, pulmonary hypertension, and heart failure with preserved ejection fraction (PH-HFpEF).

Principal Investigator Yen-Chun (Charly) Lai, PhD

Phone