Clinical Research Centers

The Indiana Clinical Research Center (ICRC), where groundbreaking medical discoveries come to life! As an integral part of the Indiana Clinical Translational Science Institute (CTSI), we have been at the forefront of clinical research since its establishment in July 1962, backed by unwavering federal funding. IUPUI campus Program Director, Dr. Scott Denne, has been leading the team since 2008, building upon the impressive legacy of Dr. Munro Peacock. Spanning across the state, our four state-of-the-art facilities offer unrivaled resources, empowering both investigators and participants to embark on an exciting journey toward transformative breakthroughs.

Since its establishment in 2010, the CTSI Human Subjects Research Recruitment Office (RRO) has been dedicated to helping Indiana CTSI investigators successfully identify and recruit participants for clinical trials. As a part of the Indiana CTSI, the Research Recruitment Office consists of a team of nine experienced staff members with over 14 years of recruitment expertise. This office provides comprehensive support to researchers, from pre-award planning to participant recruitment.

Regenstrief Institute is the central point of access to the Indiana Network for Patient Care (INPC), which contains over 15 billion observations for more than 18 million individuals since its inception, aids the RRO in determining potential patient eligibility for research trials based on specific criteria. By leveraging the information within the INPC, the RRO can approach eligible patients during their clinic appointments. Indiana CTSI investigators can request a complimentary patient eligibility assessment for clinical trials through the RRO and INPC. To approach and consent individuals for research trials, the RRO employs ResNet, a network of highly trained clinic-based personnel who actively recruit and screen patients in primary care clinics staffed by Eskenazi and IU Health. ResNet effectively matches eligible patients with the clinic's appointment system, facilitating efficient recruitment. Since 2000, ResNet has successfully recruited over 21,500 patients for more than 64 studies, supported by extramural grants totaling over $22 million. Notably, approximately 68% of the patients approached were African-American or Hispanic, highlighting the RRO's ability to recruit from diverse populations.

In addition to ResNet, the RRO maintains a volunteer recruitment registry called INresearch.org, available to all Indiana University investigators. This registry, established in 2011, aims to engage Indiana residents interested in participating in research conducted at various Indiana CTSI-affiliated institutions. By providing information about ongoing research studies at Indiana University, the registry encourages community involvement in research. INresearch.org is a free resource offered by the Indiana CTSI to assist researchers in finding willing volunteers for their studies. Researchers utilizing the INresearch.org volunteer registry collaborate with the Indiana CTSI Research Recruitment Office (RRO) to identify the specific individuals needed for their studies. Currently, there are 22,000 registered Indiana residents who have joined the registry in the past 18 months through recruitment efforts in healthcare clinics, health fairs, provider websites, and other media sources. To register, individuals create their own health profiles, which include relevant health information and medication usage, enabling them to connect with investigators and their studies