Cardiovascular Clinical Trials

The Krannert Cardiovascular Research Center at Indiana University School of Medicine offers patients with cardiovascular disease an opportunity to participate in clinical trials.

Through clinical trials, faculty try to better understand ischemic heart disease, heart failure, arrhythmia, cardio-oncology, cardio-pulmonary research, lipid disorders and health equity in cardiovascular disease. We search for solutions to slow disease progression and improve outcomes and quality of life.

We are committed to understanding, preventing and treating cardiovascular diseases and improving cardiovascular health here in Indiana and worldwide.

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A track record of excellence

Over the last 70 years, IU School of Medicine faculty have contributed to pivotal clinical research. That work has led to understanding the mechanics of fibrillation and defibrillation, the development of echocardiography and the pathogeneses and molecular mechanisms associated with heart failure. Our contributions to clinical research have helped inform how cardiologists can better care for patients at various stages of cardiovascular disease and we continue to discover new pathways to guide the profession. Many of our clinical faculty are recognized internationally for their research and clinical contributions.

Our interdisciplinary team conducts research that integrates imaging, informatics, pathology and engineering to develop novel diagnostics and therapeutics. With dedication to rigorous enrollment procedures, participants receive thorough explanations of risks and benefits before participating in clinical studies.

Studies can range from federal-funded investigator-initiated clinical trials to industry-sponsored clinical trials and foundational/non-profit-sponsored clinical trial research, like those made available through the American Heart Association and the American College of Cardiology. Our current federally funded research includes those supported by the National Institutes of Health and the U.S. Department of Defense.

Find a clinical trial

The Krannert Cardiovascular Research Center leads and contributes to clinical trials that seek participants in a variety of cardiovascular subspecialties. For clinical trial opportunities, visit All IN for Health.

Subspecialties
Arrhythmia and electrophysiology
Cardiooncology
Cardiopulmonary
Heart failure
Ischemic heart disease
Lipid disorders

Find a study

Participate in a clinical trial

Contact the Clinical Research Team to participate in a clinical trial.

Email us

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Why should I participate in a clinical trial?

An advantage of specialty cardiovascular care at an academic health center is access to clinical trials, which could provide lifesaving or life-changing alternatives to regular medical treatments. Clinical trials may be available to you at one of our affiliated clinics or a partnering site that may be closer to home. Contact us to learn more.

Clinical research has led to several advances in cardiovascular medicine since the 1950s. New and improved therapies have brought more treatment options to patients, reduced mortality and improved quality of life. These advances have ranged from implantable defibrillators, blood pressure medications, blood thinners, beta blockers and even aspirin.

Advances in clinical research are not possible without patients who volunteer to participate. Many people enroll in a clinical trial to see if their symptoms or condition can improve, to help other patients and to increase knowledge about treating and preventing cardiovascular disease.

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What do clinical trials accomplish?

Clinical trials evaluate the safety and effectiveness of a potential drug or medical device to advance medical care. Today’s treatments are based on the findings of previous clinical trials. Results of clinical trials add to the body of knowledge that the next generation of innovative therapies are based on.

Clinical trials range from an early phase to a late stage clinical trial that examines the uses of procedures or medicines that are in the last phases of approval before they become broadly available.

Am I eligible?

Clinical trials have strict eligibility requirements. Criteria may vary depending on age, gender, disease progression or other specifications outlined in the trial. Our research coordinators may be able to answer questions and help you enroll once your eligibility is confirmed. Please contact us to learn more.

You can also join the All IN for Health Registry to be alerted about an upcoming study.

This illustrates a hand of a person signing a consent form while a health care professional's hand points to the paper.

What is informed consent?

Before you or your loved one decide to enroll in a clinical trials, our team will describe the study in detail. This is an opportunity to ask questions and get them answered. They will share the possible benefits and risks of participating in specific clinical trials and outline what is required from a study participant, including the clinical trial duration. Once informed about the clinical research study, you can decide whether to enroll in a clinical trial.

Clinical trials that are offered by IU School of Medicine uphold the highest ethical standards to protect patient information and confidentiality.

Participating in clinical research is always voluntary, and you can withdraw at any time during a trial.

Our clinical research team

Our clinical research team consists of clinical research coordinators, physician-scientists, clinician research leadership and administrators to ensure the successful delivery of clinical trials from start to finish. They are responsible for the continuous enrollment of eligible participants, clinical data reporting, patient care and monitoring and ethical and regulatory concerns.

Suparna C. Clasen, MD

Director, Clinical Research Operations
Assistant Professor of Clinical Medicine

Read Bio

Doris Muriathiri, MPH, CCRP

Clinical Research Leader