Lu said developing T-Ama has been a team effort, as researchers at the Vera Bradley Foundation Center for Breast Cancer Research—such as Xinna Zhang, PhD, Bryan Schneider, MD, Milan Radovich, PhD, and Kathy Miller, MD—have collaborated with Heidelberg Pharma, a German pharmaceutical company. Zhang, Schneider, Radovich and Miller are also physician-scientists at IU School of Medicine and the IU Simon Comprehensive Cancer Center. Two of Lu’s lab members, Yujing Li, PhD, and Yifan Sun, are co-first authors of the study. Li did a large amount of the benchwork for this study, while Sun contributed on the bioinformatic side.
Lu is co-leading a cancer immunotherapy program for triple negative breast cancer as part of the Indiana University Precision Health Initiative. Zhang is also involved in the initiative for developing novel breast cancer immunotherapy. The Precision Health Initiative, the first recipient of funding from the Indiana University Grand Challenges Program, is enhancing the prevention, treatment, and health outcomes of human diseases through a more precise analysis of genetic, developmental, behavioral and environmental factors that shape an individual’s health.
This study was supported by the IU Grand Challenge Precision Health Initiative, Indiana University Strategic Research Initiative fund, Vera Bradley Foundation for Breast Cancer, and National Cancer Institute.
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