MolecuLight i:X fluorescence image reveling widespread bacterial fluorescence (red/pink color) in and around a wound.

Indiana Center for Regenerative Medicine and Engineering

The Indiana Center for Regenerative Medicine and Engineering is a multidisciplinary research center focused on the development of novel technologies that regenerate cells and tissues affected by age, disease, damage or congenital effects, ultimately leading to wound care and healing for patients in Indiana and beyond. Located on the Indiana University School of Medicine – Indianapolis campus, the center is comprised of more than 30 scientists and staff working to reduce the number of amputations in the state of Indiana and deliver critically acclaimed science.

Research Updates

To stay current on the medical research work at IU School of Medicine’s statewide campuses, follow the IU School of Medicine research blog, where investigators throughout the school’s academic departments post updates about their work.

Blog

Center Leadership

Chandan Sen, PhD

Director, Center for Regenerative Medicine and Engineering

Chandan Sen, PhD, serves as the Vice Chair of Research at Indiana University School of Medicine Department of Surgery. He also serves as the Director of the Indiana Center for Regenerative Medicine and Engineering. Dr. Sen’s team is made up of more than 30 scientists and staff who study how to tap into the power of regenerative medicine and engineering to heal burns, develop new therapies for diabetic complications, treat injured soldiers, and even regrow damaged and diseased tissue.

Check out what the Indiana Center for Regenerative Medicine and Engineering is doing in the monthly director’s update.

Mervin C. Yoder, MA, MD

Director Emeritus, Indiana Center for Regenerative Medicine and Engineering

Mervin C. Yoder, MA, MD, became an Assistant Professor of Pediatrics at the Indiana University School of Medicine in 1985. He was awarded tenure in 1991, and promoted to Professor of Pediatrics and of Biochemistry and Molecular Biology in 2000. In 2004, Dr. Yoder was named the Richard and Pauline Klingler Professor of Pediatrics. In March 2008, he was promoted to Director of the Herman B. Wells Center for Pediatric Research and Associate Chair for Basic Research in the Department of Pediatrics. In 2011 he was chosen to serve as Assistant Dean for Entrepreneurial Research for the IU School of Medicine and Associate Director for Entrepreneurship for the Indiana Clinical and Translational Sciences Institute. He was promoted to Distinguished Professor in 2013.

Check out what the Indiana Center for Regenerative Medicine and Engineering is doing in the monthly director’s update.

Gayle M. Gordillo, MD

Director of the Comprehensive Wound Care Center at IU Methodist Hospital

Gayle Gordillo, MD, is a plastic surgeon in Indianapolis, Indiana and is affiliated with Indiana University Health Medical Center. She has worked on multiple different projects studying mechanisms regulating angiogenesis in both wound healing and endothelial cell tumor biology. She has expertise in the design and execution of both sponsored clinical trials and investigator-initiated clinical and translational research. Additional funded projects that she has worked on are thermal burns, oxygen imaging, and nutritional interventions to treat diabetes and stroke. She received her medical degree from The Ohio State University College of Medicine and has been in practice for more than 20 years. She is one of 20 doctors at Indiana University Health Medical Center who specialize in Plastic Surgery Dr. Gordillo has co-authored many articles in well-known publications, including Antioxidants and Redox Signaling, Journal of Biological Chemistry, American Journal of Physiology-Cell Physiology and Plastic and Reconstructive Surgery.

Check out what the Indiana Center for Regenerative Medicine and Engineering is doing in the monthly director’s update.

Sashwati Roy, PhD

Director of Clinical Research at Comprehensive Wound Care Center at IU Methodist Hospital

Sashwati Roy, PhD is a Professor of Surgery and Director of Clinical Research at IU Health Comprehensive Wound Center. She is an expert in inflammation and macrophage biology in chronic wounds. She did her PhD from the University of Kuopio, Finland, and post-doc from the University of California, Berkeley. Her research interests include wound inflammation, mechanisms of resolution of diabetic wound infection, tissue repair, and cellular plasticity. Her laboratory recently highlighted immune cell plasticity in wound repair. The work published in Nature Communication in March 2018.

Interdisciplinary Collaboration

Regenerative medicine solutions require expertise across disciplines in medicine and engineering to develop transformative solutions in science and health care. With support from the state of Indiana, philanthropic donors, foundations and the federal government, the center partners with private industry to develop new treatments for disease.

The center’s team of investigators are located throughout the state of Indiana, converging toward excellence in regenerative medicine and engineering, in partnership with industry and government agencies. Together, this team is working to address four core pillars: Cell-Based Therapies; Tissue Engineering; Wound, Burn, and Inflammation; and Military Health.

Cell-Based Therapies

Tissue Engineering

Wound, Burn, and Inflammation

Military Medicine

Video

The power of healing through innovative technology

Indiana Center for Regenerative Medicine and Engineering

Emerging Training Program

The Center for Regenerative Medicine and Engineering at IU School of Medicine is in the process of developing the nation’s first PhD program in regenerative medicine and engineering with opportunities for industry internship.

Tissue Nanotransfection

Investigators at the Center have developed a non-invasive, nanochip device that uses tissue nanotransfection technology to reprogram one type of tissue into another with a simple touch and electric spark that is harmless to the body.

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What is regenerative medicine?

Regenerative medicine is the process of creating living, functional tissues to repair or replace tissue or organ function loss due to age, disease, damage or congenital effects.

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Schedule an Interview

To set up an interview with IU School of Medicine faculty or receive material and resources about a specific area of medical research and education, contact Christina Griffiths, media relations and communications coordinator, by phone at 317-671-3114 or by email with the link below.

Email Christina Griffiths