This project’s co-principal investigator is Navnath Gavande, PhD, a former post-doctoral researcher in Turchi’s lab who originally synthesized the new drug compounds. Gavande joined Wayne State University in 2019 as an assistant professor of pharmaceutical sciences and continues to work closely with Turchi to optimize the drug for clinical use. The project also involves collaborators Karen Pollok, PhD, and Joe Dynlacht, PhD, who bring expertise in animal models and radiation oncology. These collaborations are critical to help the researchers better understand DNA damage stress and how to use this knowledge to develop novel anticancer therapeutics.
IU School of Medicine is the largest medical school in the U.S. and is annually ranked among the top medical schools in the nation by U.S. News & World Report. The school offers high-quality medical education, access to leading medical research and rich campus life in nine Indiana cities, including rural and urban locations consistently recognized for livability.