Faculty Labs

Successful biomedical research demands collaboration among scientists with varying specialties. Faculty throughout IU School of Medicine's 25 academic departments work together to advance knowledge and treatment for patients in the world's most critical areas of medicine.

Garcia Lab

The Garcia lab (Evansville) focuses on understanding the processes of brain development and degeneration, as well as their relationships to neurological and psychiatric disorders. We use magnetic resonance imaging (MRI) and mechanics-based modeling to gain insight into the processes of brain folding, maturation, and atrophy. We also engage in collaborative clinical and translational research studies, through which we aim to eventually “bridge the gap” between scientific understanding and clinical intervention related to observed brain phenomena.

Principal Investigator Kara Garcia, PhD

Phone (812) 909-7230

Gaston Lab

The Gaston lab (Indianapolis) does basic and translational research focused on improving the management of childhood respiratory disease. The experimental methods involve cell and molecular biology, imaging, single cell analyses, biochemistry, human translational protocols and informatic analyses. Diseases studied include apnea, asthma, viral pneumonia and bronchiolitis, primary ciliary dyskinesia, bronchopulmonary dysplasia and septic shock.

Principal Investigator Benjamin Gaston, MD

Phone (317) 278-2705

Georgiadis Lab

Research in the Georgiadis lab focuses on understanding the mechanisms by which protein-nucleic acid interactions regulate biological processes including transcription, replication, and DNA repair. Investigation of these functionally significant protein-nucleic acid interactions involves structural work, primarily X-ray crystallography, NMR, and cryoEM, complementary biochemistry and/or enzymology, development of small molecule probes, and cell-based approaches. (Indianapolis)

Principal Investigator Millie M. Georgiadis, PhD

Phone (317) 278-8486

Gingery Lab

The primary focus of the Gingery Lab (Indianapolis) is on musculoskeletal pathology injury, repair, regeneration and therapeutics.

Graham Lab

The Graham Laboratory (Indianapolis) is studying the genetics of metabolic function and disease through the manipulation of genetic model systems, particularly the mouse and the fruit fly, Drosophila melanogaster.

Principal Investigator Brett A. Graham, MD

Phone

Greenfield Lab

The Greenfield Lab (Indianapolis) has long-standing research interests focusing on basic and translational aspects of bone biology, and on osteosarcoma metastasis.

Principal Investigator Ed Greenfield, PhD

Phone (317) 278-5585

Guo Lab

The Guo Laboratory (Indianapolis) focuses on the viral pathogenesis of hepatitis B virus (HBV) and antiviral discovery.

Han Lab

The long-term goal of the research in the laboratory of Renzhi Han, PhD, (Indianapolis) is to shed light on the molecular mechanisms underlying muscular dystrophy, cardiomyopathy and dyslipidemia-associated cardiovascular diseases, and to develop adeno-associated viral (AAV) based gene replacement and gene editing therapies for these genetic and metabolic diseases.

Principal Investigator Renzhi Han, PhD

Phone (317) 274-5642

Hashino Lab

The Hashino Lab (Indianapolis) leverages expertise in CRISPR/Cas9 genome-editing technology to generate inner ear/brain organoids harboring disease-associated mutations and also various reporter stem cell lines for prompt identification of specific cell types.

Principal Investigator Eri Hashino, PhD

Phone (317) 278-1215

Hato Lab

The long-term goal of the Hato Laboratory (Indianapolis) is to develop targeted therapies for acute kidney injury in sepsis. Research focuses on defining the timeline of sepsis-induced kidney injury using a combination of imaging and sequencing tools.

Principal Investigator Takashi Hato, MD

Phone