Basic scientists at Indiana University School of Medicine conduct leading-edge research on the neurobiology and molecular genetics of Alzheimer’s disease to define disease mechanisms using animal models, identify therapeutic targets, rigorously test drugs using preclinical testing protocols, and create molecules for potential drugs.
Researchers span many departments at IU School of Medicine and many collaborate on their investigations and grant-funded research through the Stark Neurosciences Research Institute. Model Organism Development and Evaluation for Late-Onset Alzheimer’s Disease (MODEL-AD) and the Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) work in tandem to advance discoveries in Alzheimer's research. The two National Institutes of Health funded grant programs are among the largest federally-funded studies at IU.