Wu Lab

The research lab of Yu-Chien Wu, MD, PhD, is actively investigating a wide range of radiology and imaging topics. Dr. Wu is particularly focused on studying diffusion physics in biologic system using diffusion MRI.

members of the wu lab

Wu Lab featured in national IU commercial

Expertise

The Wu Lab is a national leader in neuroscience expertise. From working on studies like the CARE Consortium, the world's most comprehensive concussion study, to uncovering early diagnosis treatments for Alzheimer's disease, the Wu Lab is a pioneering hub for research excellence at IU School of Medicine and across the country.


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Stay up to date on the latest research by the Wu Lab and reach out to current team members.

14 countries represented
$11 million in grant funding
213 publications
Research Topics
Images of brain scans for Alzheimer's.

Alzheimer's disease

With current treatments only managing symptoms, research is needed to address early diagnosis and intervention.

Imagings of brain scans for animials.

Animal Imaging

In vivo assessments on a mouse model find disruptions in microstructural integrity and neurite organization.

Images of brain scans for concussion.

Sport-Related Concussion

The relationship between blood-based neural biomarkers and white matter neuroimaging in collegiate athletes.

Images of brain scans.

Human Imaging

The lab highlights the growing impact of computational methods, combined imaging techniques, and animal models in advancing neuroscience research.

Images of brain scans for TBI.

Traumatic Brain Injury (TBI)

The lab addresses the sensitivity issues of conventional medical imaging techniques in detecting mild traumatic brain injury (mTBI) by utilizing hybrid diffusion imaging (HYDI).

Research Funding

Salman Shahid (left) and Yu-Chien Wu (right) sitting on a bench smiling at the camera. A small tree is in the background.

Research collaborations are pivotal in advancing research within the Wu Lab. These partnerships help foster synergy, pooling diverse expertise and resources to tackle complex challenges. From access to specialized equipment, funding, and data, to amplifying research capabilities — shared knowledge accelerates innovation, refining diagnostic techniques and potential treatment strategies.

Ultimately, partnerships amplify a lab's impact, driving transformative progress in neuroscience.

news & publications

Dr. Wu wins Radiology Faculty Mentorship Award

Yu-Chien Wu, MD, PhD, was recently recognized with the 2024 Radiology Faculty Mentorship Award.

The award was established to recognize faculty mentors in the Department of Radiology and Imaging Sciences who exemplify excellence as they support and contribute to the career development and advancement of other faculty members and learners (students, residents, fellows and postdocs) in the areas of research, education, service and/or clinical practice. 

Alterations of brain microstructures in mouse model

Images of six brain scans over black background.

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Differential vulnerability of hippocampal microstructure

Two images of brain scans.

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Understanding the role of amyloid to cerebral microvasculature in AD

Images of brain scans in grays, blues and greens over black background.

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Role of neurochemistry in amyloid pathology

Image of graph

View Abstract