Alzheimer's disease

The projected rise in Alzheimer's disease cases underscores the urgency of finding effective treatments, as current options only manage symptoms. Early intervention before significant cognitive decline is vital, necessitating reliable biomarkers to identify at-risk individuals. Promising research on quantitative cerebral blood flow suggests its potential as an early biomarker, but further studies are needed to fully understand its spatiotemporal patterns in Alzheimer's disease and to account for potential confounding factors in analyses.

Images of brain scans for Alzheimer's

Active Research

Assessing Diffusion MRI Metrics for Detecting Changes of Synaptic Density in Alzheimer's Disease

Grant: R01AG083951
PI: Yu-Chien Wu and Scott Snyder
2023-28
Imaging Signatures of Anticholinergic Medications in the Context of Alzheimer's Disease and Related Dementia (ADRD) Biomarkers

Grant: R01AG085547
PI: Shannon Risacher
2023-28
Investigating Pathways from Adverse Pregnancy Outcomes to Alzheimer's Disease and Related Dementias: the nuMoM2b-Brain Study

Grant: R01 PAR-22-093
PI: E. Miller, E. and David Haas
2023-28
Long-Term Nicotine Treatment of Mild Cognitive Impairment

Grant: R01AG047992
PI: P. Newhouse, P. and Andrew Saykin
2023-27
IU/JAX/PITT MODEL-AD Center

Grant: U54AG054345
PI: Bruce Lamb, Adrian Oblak and Paul Territo
2022-27
Indiana Alzheimer's Disease Research Center

Grant: P30AG072976
PI: Andrew Saykin
2021-26
Multi-Domain Sensory Measures as Biomarkers of Alzheimer's Disease in Preclinical and Prodromal Stages

Grant: R01AG061788
PI: Shannon Risacher
2019-23

Get Research Updates

To stay current on the medical research work at IU School of Medicine’s statewide campuses, follow the IU School of Medicine research blog, where investigators throughout the school’s academic departments post updates about their work.

Blogs Hub

Discover active research areas