Faculty Labs

Successful biomedical research demands collaboration among scientists with varying specialties. Faculty throughout IU School of Medicine's 25 academic departments work together to advance knowledge and treatment for patients in the world's most critical areas of medicine.

Hawkins Lab

Investigators in the Hawkins laboratory (Indianapolis) use next generation sequencing, mouse models, 3D bioprinting, and human samples to study benign and malignant diseases of the female reproductive tract, including endometriosis, endometriosis-associated ovarian cancer, endometrial dysfunction, and endometrial cancer.

Principal Investigator Shannon M. Hawkins, MD, PhD

Phone

Herbert Lab

The Herbert Lab (Indianapolis) studies the roles of telomeres and telomerase in aging and cancer.

Principal Investigator Brittney-Shea Herbert, PhD

Phone (317) 278-6147

Herzog Lab

The Herzog Lab (Indianapolis) develops adeno-associated viral (AAV) based gene therapies and immune tolerance induction protocols for the X-linked bleeding disorder hemophilia and other diseases. Investigations aim at uncovering immune mechanisms leading to rejection or, conversely, lasting therapy. Detailed studies address the interactions between the viral vector and its transgene products and the immune system.

Principal Investigator Roland W. Herzog, PhD

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Huang Lab

The Huang Lab (Indianapolis) is focused on uncovering how NQO1 bioactivatable drugs stimulate anti-cancer immunity. The goal is to develop novel antitumor therapies to treat cancers with elevated levels of NQO1.

Principal Investigator Xiumei Huang, PhD

Phone 317-278-6449

Huang Lab

The lab of Yunjie Huang, PhD, (Indianapolis) is interested in the cellular quality control systems for the biogenesis of membrane proteins. The lab focuses on a multi-pass transmembrane protein called cystic fibrosis transmembrane conductance regulator (CFTR) to identify the potential therapeutic targets that may lead to novel treatment for the underlying diseases. Dr. Huang conducts his research within the Pediatric Translational Research program at the Herman B Wells Center for Pediatric Research.

Principal Investigator Yunjie Huang, PhD

Phone (317) 274-8931

Hulvershorn Lab

The research lab (Indianapolis) of Leslie Hulvershorn, MD at Indiana University School of Medicine is focused on understanding more about risky decision-making in youth, including how the brain processes risky decisions and how it influences health like acquiring infectious diseases, suicidal behavior and using drugs of abuse.

Principal Investigator Leslie A. Hulvershorn, MD

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Hurley Lab

The Hurley Lab (Indianapolis) is exploring, at the molecular level, the processes involved in the recognition and binding of molecules that are directed to the active sites of enzymes. Recent work has challenged the team to understand the functional distinction between active site directed inhibitors as well as activators.

Principal Investigator Thomas D. Hurley, PhD

Phone (317) 278-2008

Hurwitz Lab

The laboratory of Stephanie Hurwitz, MD, PhD, (Indianapolis) seeks to better understand the interaction of hematopoietic stem and progenitor cells (HSPCs) with the bone marrow microenvironment. Using a variety of in vitro and in vivo models, the lab studies the complex HSPC-niche signaling that underlies physiologic and therapeutic mechanisms of HSPC marrow homing and niche occupancy.

Principal Investigator Stephanie Hurwitz, MD, PhD

Phone

Ivan Lab

The Ivan Lab (Indianapolis) is studying the metabolic branches of the hypoxic response and how they can be exploited for synergistic anticancer combinations in solid tumors (with emphasis on brain cancer).

Principal Investigator Mircea Ivan, MD, PhD

Phone

Jin Lab

Research in the Jin Lab (Indianapolis) focuses on the organization and plasticity of neural circuits in the cerebral cortex, and the mechanisms of epileptogenesis following traumatic brain injury.

Principal Investigator Xiaoming Jin, MD, PhD

Phone (317) 278-5766