The Hawkins laboratory focuses on studying benign and malignant diseases in the female reproductive tract. Researchers in this lab study ovarian cancer from the perspective of the endometriotic tumor microenvironment. They also create models that recapitulate human disease. In addition, the lab is active in training gynecologists, emergency medicine physicians and medical, graduate, undergraduate and high school students.
Published Work
View a complete list of published work by the Hawkins Laboratory.
Endometriosis
The Hawkins Lab uses well-characterized endometriosis tissues and next generation sequencing as an unbiased approach to determining new pathways that can be targeted for therapy.
Ovarian Cancer
The Hawkins Lab is developing a 3D-bioprinted model of ovarian cancer within the endometriotic tumor microenvironment.
Endometrial Cancer
The Hawkins Lab is focusing on steroid hormone effects, the role of specific miRNA molecules in aggressive tumors and the role of uterine stem cells in endometrial cancer.
Active Research
- Creation and Validation of Novel Mouse and In Vitro Models of Endometriosis
- 3D Bio-Assembled Model of Endometriosis-Associated Ovarian Cancer Using the Kenzan Method
- Dissecting the Role of ARID1A in Ovarian Cancer Using a 3D Bio-Assembled Model of the Endometriotic Tumor Microenvironment
- Novel Integration of miRNA for Discovery of Unique Molecular Networks in Endometrioid Ovarian Cancer with Concurrent Endometriosis
- Biologic and Molecular Impact of Dicer Haploin Sufficiency on miRNA Processing, Tumor Transcriptome and RNA Binding Proteins in the Pathogenesis of Endometrial Cancer
Research Team
Shannon M. Hawkins, MD, PhD
Associate Professor of Obstetrics & Gynecology
Yuliya Klymenko, MD, PhD
Assistant Research Professor of Obstetrics & Gynecology
The research team also includes Kaitlyn Collins, Medical Science Training Program (MSTP) student.