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Top 10 recipients of NIH funding for federal fiscal year 2019

NIH awards Liana Apostolova

Liana Apostolova, MD, MSc, FAAN, and Apoorva Sanjay Bharthur

Liana Apostolova, MD, MSc, FAAN, and Apoorva Sanjay Bharthur

At Indiana University School of Medicine, the 2019 fiscal year set another record for NIH-funded research, with the school’s faculty attracting federal support for research targeting Alzheimer’s disease, pediatric health, global research and more. Here are the projects that were awarded the largest grants:

1. Longitudinal Early-Onset Alzheimer’s Disease Study, led by Liana Apostolova, MD, MSc, FAAN – $14,470,241

This is a two-year observational study designed to look at disease progression in adults with early-onset Alzheimer’s disease (between ages 40-64). Researchers are also recruiting cognitively normal volunteers for a one-year comparison.

2. National Cell Repository for Alzheimer’s Disease, led by Tatiana Foroud, PhD – $11,163,442

This is a program where researchers store and provide biological materials (like DNA, plasma and brain tissue) which enable Alzheimer’s disease research locally and nationwide.

3. Indiana Clinical and Translational Sciences Institute, led by Anantha Shekhar, MD, PhD – $6,615,062

This institute works to accelerate research, grow talent and improve health by bringing together Indiana’s brightest minds to solve the state’s most pressing health challenges.

4. Indiana University/ Jackson Laboratory Model Organism Development & Evaluation for Late-Onset Alzheimer’s Disease, led by Bruce Lamb, PhD – $6,508,146

This consortium is working to develop the next generation of in vivo Alzheimer’s disease models based on human data for researchers across the country.

5. Alzheimer’s Disease Drug Discovery Center, led by Alan Palkowitz, PhD – $5,774,436

Researchers at this center are working to improve, diversify and reinvigorate the Alzheimer’s disease drug development pipeline.

6. International epidemiology Databases to Evaluate AIDS, led by Kara Kay Wools-Kaloustian, MD – $3,729,014

This international research consortium works to collect, consolidate and analyze data about treatment of HIV and evaluates outcomes of people living with HIV/AIDS.

7. Indiana Alzheimer’s Disease Center, led by Andrew Saykin, PSYD – $2,870,314

This is one of 32 Alzheimer’s disease research centers that are national hubs for clinical trials and patient support programs.

8. Implementing Genomics in Practice, led by Todd Skaar, PhD – $2,795,541

The goals of this project are to recruit minority and underserved patients and test effects of genotype-guided opioid therapy on pain control and opioid-related adverse events.

9. Indiana University Simon Cancer Center, led by Pat Loehrer, MD – $2,759,704

This grant supports basic and translational research being done at the IU Simon Cancer Center.

10. Morphogenesis and growth of the ventricular wall in development and disease, led by Anthony Firulli, PhD – $2,386,125

Pediatric researchers are working to understand the role certain proteins play during heart development, as they strive to minimize congenital heart defects, which are the most common birth defect.

The views expressed in this content represent the perspective and opinions of the author and may or may not represent the position of Indiana University School of Medicine.
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Anna Carrera

Research Communications Manager

Anna Carrera is the research communications manager for Indiana University's Precision Health Initiative, IU School of Medicine and the Indiana Clinical and Translational Sciences Institute. She joined the team in June 2019 after working as a TV news rep...