IU USCAP Presentations
March 23
10:30 AM - 12:30 PM
BCEC Room 210 A
COMPANION MEETING: International Society of Bone & Soft Tissue Pathology
The Classification of Rhabdomyosarcoma, Beyond FOXO1!
Carina A. Dehner, MD, PhD
5:30 PM - 7:30 PM
BCEC NW Lobby A
FELLOWSHIP FAIR
March 24
8:00 AM - 12:00 PM
BCEC Room 210 A
Platform - Dermatopathology
Moderators: Matthew Kuhar, MD , Wonwoo Shon, DO
11:45 AM - 12:00 PM
BCEC Room 205 PM B
PLATFORM - GENITOURINARY PATHOLOGY
Analysis of microRNA 371-373 Cluster and 12p Status in Somatic Carcinomas with Phenotypic Similarities to Yolk Sac Tumor
J. Lobo; N. Tavares; D. Fonseca; R. Henrique; C. Jeronimo; C. Ricci; A. De Leo; T. Ulbright; S. Gupta; A. Acosta
1:15 PM – 1:30 PM
BCEC Room 210 B
PLATFORM - GI PATHOLOGY
Clinicopathologic and Molecular Characterization of Primary Anorectal Mucosal Melanomas
Y. Feng; S. Zhang; C. Dehner; B. Umphress; I. González
1:30 PM – 1:45 PM
BCEC Room 205 B
Platform - Genitourinary Pathology
Renal Sarcoma with MEIS1::NCOA1 Fusion: A Rare Entity with Pathologic Overlap with Mixed Epithelial and Stromal Tumor and Metanephric Stromal Tumor
B. Smith; P. Argani; S. Wangsiricharoen; K. Wakeman; Y. Neff; M. Tretiakova; F. Brimo; K. Collins; S. Falzarano; J. Gross; C. Antonescu; A. Agaimy; G. Charville; A. Sangoi
PLATFORM- GENITOURINARY PATHOLOGY
Comprehensive microRNA Profiling of Testicular Leydig Cell Tumors Supports the Existence of a Signature Predictive of Malignant Behavior -
J. Lobo; N. Tiago Tavares; D. Fonseca; V. Constâncio; A. Teixeira Marques; R. Henrique; C. Jeronimo; K. Michalova; K. Cornejo; M. Colecchia; C. Ricci; M. Idrees; F. Contreras; I. Fernandez; W. Anderson; F. Maclean; A. Osunkoya; C. Kao; T. Ulbright; A. Acosta
2:15 PM – 3:00 PM
BCEC Room 207
Short Course 02 - Bone and Soft Tissue Pathology
Classic and Emerging Fusion-Driven Mesenchymal Neoplasms: An Overview and Practical Approach
Carina A. Dehner, MD
March 25
10:00 AM - 11:30 AM
BCEC Room 156 A
INTERACTIVE MICROSCOPY IM21 - BONE AND SOFT TISSUE PATHOLOGY
Benign and Malignancy Giant Cell-Ric Lesions: An Overview and A Practical Approach
Carina A. Dehner, MD, PhD
2:00 PM - 2:15 PM
BCEC Room 210 A
Platform - Genitourinary Pathology
Perivascular Epithelioid Cell Tumors of the Urinary Bladder: A Clinicopathologic and Comprehensive Molecular Analysis including Microsatellite Instability Status and Tumor Mutational Burden in a Contemporary Cohort of 21 cases
A. Lobo; A. Tiwari; A. Agaimy; M. Akgul; A. Sangoi; S. Kandukuri; A. Acosta; K. Al-Obaidy; S. Jha; S. Kaushal; S. Satturwar; J. Dhillon; A. Osunkoya; S. Williamson; D. Pradhan; R. Shah; A. Parwani; L. Cheng; S. Mohanty
1:O0 PM - 1:15 PM
BCEC Room 210 B
Platform - Gastrointestinal Pathology
Gastrointestinal Neuroendocrine Carcinoma Associated with Adenoma: A Tumor More Aggressive than Neuroendocrine Carcinoma Mixed with Adenocarcinoma
R. Sekhri; X. Liu; K. Kang; D. Zhang; I. González; R. Gonzalez; X. Zhang; X. Wang; X, Liao; Z. Yang; L. Wang; M. Westerhoff; J. Cheng; H. Wang; W. Yu; W. Choi; Y. Xue; A. Anzar; L. Alpert; P. Toro; S. Karaaslan; J. Sweeney; X. Zhang; D. Allende; S. Hu
1:45 PM - 2:00 PM
BCEC Room 205 A
PLATFORM - BONE AND SOFT TISSUE PATHOLOGY
Atypical Spindle Cell/Pleomorphic Lipomatous Tumor: Where to draw the Line?
C. Dehner; J. Torres-Mora; J. Thangaiah; L. Warmke; R. Youssef; J. Davis; R. Naous; A. Alani; J. Chrisinger; A. Oliveira; J. Molligan
March26
8:00 AM - 9:30 AM
BCEC Room 155
INTERACTIVE MICROSCOPY IM33: BONE AND SOFT TISSUE PATHOLOGY
Soft Tissue Tumors With Unique Molecular Alterations: Morphological Features, Novel Immunohistochemical Markers and Molecular Testing
Shaoxiong Chen, MD, PhD
10:00 AM - 10:45 AM
BCEC Room 257 A
Short Course 59: Genitourinary Pathology
The Genitourinary Pathology That No One Talks About
Giovanna Giannico, MD
11:50 AM - 12:10 PM
BCEC Room 210 C
Long Course: BONE AND SOFT TISSUE PATHOLOGY
Keeping it Real: Merging Traditional and Contemporary Practices in Musculoskeletal Pathology
Emerging Molecular-Defined Bone and Soft Tissue Diagnoses: When do They Matter?
Jessica Davis, MD
1:30 PM - 3:00 PM
BCEC Room 156 A
INTERACTIVE MICROSCOPY IM42: GI PATHOLOGY Malignant Neoplasms of Anal Canal and Perianal Skin: A Practical Approach and HPV Status
Dongwei Zhang, MD, PhD
3:30 PM - 4:15 PM
BCEC Room 251
Short Course 57: Genitourinary Pathology
A Practical Approach to the Evaluation of Chemo-Naïve and Post-Chemotherapy Testicular Germ Cell Tumors
Andres Acosta, MD
6:00 PM - 8:30 PM
BCEC Room 205 B
Evening Specialty Conference - GENITOURINARY PATHOLOGY
New Kid on the Block
Andres Acosta, MD
IU USCAP Posters
March 24
9:30 AM - 12:00 PM
EXHIBIT HALL
POSTER (#55) Stowell-Orbison – Cytopathology
Epstein-Barr Virus Positive Inflammatory Follicular Dendritic Cell Tumor and Epstein-Barr Virus-Associated Smooth Muscle Tumor Exhibit Distinct Methylation Profiles
A. Valesano; A. Perry; J. Liu; C. Dehner; O. Saeed; D. Grier; A. Kovach; D. O'Malley; I. Siddiqi; E. Moore; M. Nasr; S. Tucker; J. Song; N. Brown; R. Bell
POSTER (117) – Stowell-Orbison - Gastrointestinal Pathology
Clinicopathologic and Molecular Characterization of Primary Anorectal Mucosal Melanomas
Y. Feng; S Zhang; C. Dehner; B. Umphress; I. González
POSTER (#124) Stowell-Orbison - Gastrointestinal Pathology
Gastrointestinal Mixed Neuroendocrine Non-Neuroendocrine Neoplasm: Assessment of the Validity of the 30% Requirement for Both Components
P. Toro; S. Karaaslan; X. Liu; L. Kang; D. Zhang; I. González; R. Gonzalez; X. Zhang; X. Wang; X. Liao; Z. Yang; L. Wang; M. Westerhoff; J. Cheng; H. Wang; W. Yu; W. Choi; Y. Xue; A. Anzar; L. Alpert; R. Sekhri; J. Sweeney; X. Zhang; D. Allende; S. Hu
Poster (#155) Stowell-Orbison - Liver Pathology
Histologic Features of Liver Biopsies in Patients with Hemophagocytic Lymphohistiocytosis: A Multi-Institutional Study of 16 Cases
A. Besen; S. Hu; W. Choi; D. Zhang; X. Liao
POSTER (#166) Stowell-Orbison - Genitourinary Pathology
Poor Clinical Outcomes in Testicular Germ Cell Tumor Teratomas That Fail to Meet Somatic-Type Malignancy Diagnostic Criteria
J. Williams; M. Hirsch; A. Acosta; S. Siegmund
POSTER (#185) – STOWELL- ORBISON - GENITOURINARY PATHOLOGY
Genome-wide copy-number landscape of germ cell tumor with so-called “somatic-type” malignancies
M. Hruby; K. Michalova; P. Martinek; N. Baniak; J. Gordetsky; M. Idrees; W. Anderson; T. Ulbright; A. Acosta
Poster (# 211) - Stowell-Orbison - Gynecologic and Obstetric Pathology
Comprehensive Immunohistochemical Characterization of Yolk Sac Tumors of the Ovary and Testis: New Diagnostic Value of FoxA2
A. Orsatti; S. Melotti; M. Sirolli; M. Grillini; A. Costantino; E. Franchini; G. Santandrea; J. Lobo; A. Acosta; M. Fiorentino; G. Tallini; C. Ricci; A. De Leo
Poster (# 233) Stowell-Orbison - Gynecologic and Obstetric Pathology
BAP1-Mutant Sex Cord-Stromal Tumors: Expanding the Morphologic Spectrum and Evaluation of DNA Methylation Signatures
C. Desai; H. Zullow; A. Acosta; Q. Lin; G. McCluggage; J. Bennett
POSTER (#242) STOWELL- ORBISON - PEDIATRIC AND PERINATAL PATHOLOGY
Gastric Intestinal Metaplasia in Pediatric Patients: A Metaplastic Process or an Incidental Finding?
M. Shaheen; I. González
1:00 PM - 4:30 PM
EXHIBIT HALL
Poster (#89) - Bone and Soft Tissue Pathology
Expanding the Morphologic and Molecular Spectrum of Extraskeletal Myxoid Chondrosarcoma: A Histopathologic and Molecular Study of 36 Genetically Confirmed Cases, Including EWSR1::NR4A3 and Non-EWSR1::NR4A3 gene fusions
S. Alvand; C. Dehner; G. Pujari; J. Thangaiah; J. Molligan; M. Shahi; K. Halling; S. Gupta; M. Atiq; B. Kipp
Poster (#116) Education
Expanding Continuing Pathology Education Beyond One Institution: Utilization of Zoom for Cost-Effective Regional Pathology Case Sharing
K. Byrnes; S. Ballentine; A. Dessain; L. Kang; C. Ma; P. Navale; Y. Xue; F. Yin; D. Zhang; L. Ha; X. Liu
Poster (#146) Genitourinary Pathology
Visium-HD Spatial RNAseq Analysis of Aggressive Prostatic Adenocarcinoma (PCa) Identifies Distinct RNA Signatures That Distinguish Between Gleason Grade 4 and 5 Tumors, and Subset Associated with Stroma Adjacent to PCa
C. Moreno; R. Shiradkar; T. Pathak; K. Hammouda; I. Lawal; O. Abiodun-Ojo; M. G. Sanda; D. Schuster; A. Osunkoya
Poster (#146) Genitourinary Pathology
Immune Response Transcriptional Pathways are Downregulated in Cribriform vs Non-Cribriform Prostate Cancer: A Laser Capture Microdissection Study
G. Fanelli; A. Acosta; R. Umeton; B. Robinson; F. Khani; M. Hirsch; H. Pakula; C. Scatena; A. Naccarato; M. Loda
Poster (#164) Genitourinary Pathology
Post-therapeutic Squamous Cell Transformation of Metastatic Prostatic Adenocarcinoma with Paired Molecular Profiling: A Multi-Institutional Cohort of an Under-reported Entity
S. Kaushal; J. Dhillon; V. Malik; M. Akgul; A. Acosta; A. Lobo; S. Smith; M. Aron; K. Al-Obaidy; S. Williamson; A. Sangoi; L. Cheng; M. Amin; T. Lotan; S. Mohanty
Poster (#193) Pediatric and Perinatal Pathology
Molecular Insight into Nephroblastoma-like Lesions in Germ Cell Tumors: A Comparative Study of Prepubertal-type and Postpubertal-type Teratomas
M. Hruby; K. Michalova; J. Bridge; I. Fernandez; M. Robledo Arribas; F. Contreras; S. Wobker; T. Ulbright; I. González; A. Acosta
Poster (#194) Pediatric and Perinatal Pathology
Barrett Esophagus in Children is Likely an Incidental Finding of Uncertain Clinical Significance: a Single Center Experience
M. Shaheen; I. González
Poster (#195) Pediatric and Perinatal Pathology
Evaluating Intestinal Metaplasia in Pediatric Gallbladder Specimens: Clinicopathologic Significance and Sampling Thresholds
A. Akinsanya; I. González
March 25
9:30 AM - 12:00 PM
EXHIBIT HALL
Poster (#121) Genitourinary Pathology
Expanding Horizons: A Deeper Dive into the Morphologic and Genomic Landscape of ALK-Rearranged Renal Cell Carcinomas
A. Lobo; A. Sangoi; K. Al-Obaidy; M. Akgul; A. Acosta; S. Kandukuri; S. Jha; S. Kaushal; S. Satturwar; A. Osunkoya; A. Parwani; J. Dhillon; S. Williamson; R. Shah; L. Cheng; S. Mohanty
Poster (#122) Genitourinary Pathology
Do Urinary Bladder Smooth Muscle Neoplasms Show Morphologic and Immunophenotypic Features of Their Uterine Fumarate Hydratase-Deficient Counterparts?
H. Gao; D. Ren; G. Giannico; F. Khani; L. Galea; K. Al-Obaidy; S. Falzarano; S. Wobker; K. Barry-Holson; E. Chan; A. McHenry; A. Sangoi
POSTER (#113) – LIVER PATHOLOGY
Tucatinib (HER2 Tyrosine Kinase Inhibitor)-Induced Liver Injury
Y. Feng; I. González; D. Zhang
Poster (#140) Gynecologic and Obstetric Pathology
Genome-Wide Methylation Profiling of STK11 Adnexal Tumor and Morphological Mimickers
M. Goel; H. Zullow; A. Acosta; Q. Lin; R. Young; E. Oliva; J. Bennett
1:00 PM - 4:30 PM
EXHIBIT HALL
Poster (#146) - Genitourinary Pathology
Osteoclast-Rich Undifferentiated Urothelial Carcinoma: An Expanded Immunohistochemical and Molecular Profiling with Classification Re-assessment
C. Rizkalla; M. Tretiakova; C. Suarez; S. Williamson; K. Al-Obaidy; A. Acosta; M. Idrees; E. Chan; S. Potterveld; A. Sangoi
Poster #149) - Genitourinary Pathology
GATA3 is Underexpressed in Penile Neoplasia: Potential Implications in Diagnosis and Pathogenesis
N. Kandiyil; A. Sangoi; J. Kim; C. Rodriguez; D. Tifrea; F. Rahmatpanah; C. Granada; G. Giannico
Poster (#156) - Genitourinary Pathology
DNA-sequencing Study of Low Grade Urachal Mucinous Cystic Tumors Suggest a KRAS-independent Pathogenesis
K. Michalova; J. Gordetsky; A. Sangoi; Kristine Cornejo; P. Martinek; N. Ptakova; Michael Michal; Michal Michal; A. Acosta
Poster (#136) Pancreas, Gallbladder, Ampulla, and Extra-Hepatic Biliary Tree
Pancreatobiliary and Ampullary Mixed Neuroendocrine Non-neuroendocrine Neoplasms: Any Percentage of Neuroendocrine Carcinoma is Aggressive
S. Karaaslan; X. Liu; L. Kang; D. Zhang; I. González; R. Gonzalez; X. Zhang; X. Wang; X. Liao; Z. Yang; L. Wang; M. Westerhoff; J. Cheng; H. Wang; W. Yu; W. Choi; Y. Xue; A. Anzar; L. Alpert; R. Sekhri; P. Toro; O. Basturk; N. Adsay; J. Sweeney; X. Zhang; S. Hu; D. Allende
March 26
9:30 AM - 12:00 PM
EXHIBIT HALL
Poster (#90) Liver Pathology
Hepatic Histoplasmosis as the First Manifestation in Liver Biopsy
A. Abu-Salah; G. Sheng Lei:; I. González; R. Relich; S. Mi Lee; D. Zhang
Poster (#96) Liver Pathology
The Impact of Donor Liver Frozen Evaluation in Organ Disposition and Graft Function: A Single Center Experience
Y. Feng; O. Saeed; M. Mustafa; M. Saad; S. Segura; T. Hou; K. Collins; S. Mi Lee; J. Lin; O. Cummings; D. Zhang; C. Kubal; I. González
Poster (#46) Gastrointestinal Pathology
Eosinophil-rich Esophagitis Pattern in Patients with Allogenic Hematopoietic Stem Cell Transplantation: A Multicenter Experience
R. Youssef; K. Wah Wen; Z. Alipour; S. Hu; S. Schechter; J. Cheng; I. González
Poster (#64) Gastrointestinal Pathology
Acinar and Mixed Acinar Neuroendocrine Carcinomas of the Stomach: Rare Tumors that are Often Misdiagnosed as Well-Differentiated Neuroendocrine Tumor
K. Mora; R. Gonzalez; I. González; K. Stashek; Z. Alipour
Poster (#116) Genitourinary Pathology
Current Reporting Trends, Practices, and Resource Utilization in Penile Cancer: A Survey among Genitourinary Pathologists
J. Dhillon; A. Lobo; M. Akgul; A. Acosta; V. Chumbalkar: A. Vosoughi: H. Xu; H. Al-Ahmadie; K. Al-Obaidy; M. Amin; M. Aron; S. Arora; P. Ayyanar; N. Bakshi; B. Balzer; A. Bardia; P. Baweja; I. Chakrabarti; L. Cheng; L. Cima; M. Colecchia; K. Collins; E. Compérat; D. Das; M. Dixit; M. Downes; P. Elhence; J. Epstein; L. Galea; J. Gandhi; G. Giannico; J. Gordetsky; G. Gupta; N. Gupta; A. Haider; D. Hansel; A. Hartmann; C. Ho-Yen; K. Iczkowski; E. Jain; R. Jain; S. Jha; C. Kao; S. Kaushal; G. van Leenders; K. lenka; J. Lopez; A. Lopez-Beltran; D. Luthringer; F. Maclean; C. Magi-Galluzzi; V. Malik; C. Manini; G. Martignoni; B. Mehta; S. Menon; S. Misra; S. Mohanty; R. Montironi; S. Nayak; J. Nguyen; C. Ntala; P. Oliveira; A. Osunkoya; S. Patil; M. Picken; Dr Prachi; D. Pradhan; S. Prendeville; F. Queipo; G. Quiroga-Garza; B Vishal Rao; P. Rao; M. Raspollini; S. Sabnis; S. Sancheti; D. Sanchez; J. Sarungbam; R. Satarkar; S. Satturwar; N. Sayyed; R. Shah; I. Sharma; N. Sharma; S. Sharma; D. Sirohi; P. Sobti; S. Soni; S. Sreeram; S. Sundaram; P. Tamboli; N. Tanveer; S. Tickoo; A. Tiwari; R. Tomar; M. Tretiakova; K. Trpkov; T. Tsuzuki; J. Warrick; M. Zhou; A. Sangoi; S. Williamson; S. Mohanty
POSTER (#136) Genitourinary Pathology
Interobserver Reproducibility of Pelvicalyceal Invasion in Renal Cell Carcinomas Among Genitourinary Pathologists
A. Sangoi; M. Akgul; A. Mubeen; R. Humble; A. Acosta; M. Amin; M. Aron; F. Brimo; E. Chan; L. Cheng; J. Cheville; K. Collins; K. Cornejo; J. Dhillon; M. Downes; J. Epstein; M. Hirsch; P. Kapur; A. Lobo; R. Mehra; S. Mohanty; G. Netto; A. Osunkoya; G. Paner; P. Rao; R. Saleeb; R. Shah; S. Shen; S. Smith; S. Tickoo; M. Tretiakova; K. Trpkov; S. Wobker; P. Tamboli; D. Zynger; S. Williamson
Poster (#150) Genitourinary Pathology
Interobserver Reproducibility of Hilar Soft Tissue Invasion in Testicular Germ Cell Tumors Among Genitourinary Pathologists
D. Wu; M. Akgul; S. Williamson; A. Acosta; K. Al-Obaidy; M. Amin; D. Berney; F. Brimo; L. Cheng; M. Colecchia; E. Compérat; K. Cornejo; J. Dhillon; M. Downes; J. Epstein; M. Hirsch; R. Jimenez; A. Lobo; S. Kaushal; A. Lopez-Beltran; S. Mohanty; R. Mehra; G. Paner; P. Rao; V. Reuter; R. Shah; S. Shen; S. Smith; M. Tretiakova; K. Trpkov; S. Wobker; P. Tamboli; D. Zynger; A. Sangoi
1:00 PM - 4:30 PM
EXHIBIT HALL
Poster (#114) Gastrointestinal Pathology
Clinicopathologic Characterization of Incidental Findings in Multivisceral Transplants: A Single Center Experience
H. Hyaduck; R. Mangus; I. González
Poster (#221) Hematopathology
Clinical Validation of a Novel Comprehensive Next Generation Sequencing Assay for Hematolymphoid Malignancies
L. Wang; L. Happ; K. Xu; K. Ofori; A. Vrydaghs; R. Sperling; J. Loy-Flynn; S. Dave: M. Czader
Poster (#140) Genitourinary Pathology
Determinants of Oncologic Outcomes in High Grade Organ-Confined Prostate Cancer After Radical Prostatectomy
R. Youssef; O. Saeed; E. Baraban; M. Salimian; K. Iczkowski; L. Chung; N. Baniak; E. Compérat; H. Miyamoto; G. van Leenders; A. Sangoi; D. Wu; A. Osunkoya; S. Kandukuri; K. Michalova; G. Martignoni; L. Marcolini; A. Caliò; A. Pecoraro; A. Strakova-Peterikova; Y. Wang; A. Cuber; T. Tsuzuki; A. Acosta
Poster (#186) Gynecologic and Obstetric Pathology
NR4A3-Rearranged Sarcomas of Gynecologic (GYN) Tract: Expanding the Spectrum of Morphologic and Immunohistochemical Findings
S. Alvand; G. Pujari; C. Dehner; J. Chrisinger; B. Kipp; S. Martin; C. Gilks; M. Atiq; K. Halling; J. Torres-Mora; M. Shahi
Poster (#91) Head and Neck Pathology
Adenoid Cystic Carcinomas with Amplification of KDR, KIT and PDGFRA: Histologic Features and Comprehensive Molecular Genetic Findings
M. Hussein; E. Honaker; S. Rock; J. Dueber; D. Allison; T. Bocklage