Skip to main content
Indiana O'Brien Center for Advanced Renal Microscopy and Molecular Imaging

Most Current Publications

Bryniarski MA, Sandoval RM, Ruszaj DM, Fraser-McArthur J, Yee BM, Yacoub R, Chaves LD, Campos-Bilderback SB, Molitoris BA, Morris ME. Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide. Mol Pharm. 2023 Feb 6;20(2):987-996. eng. Epub 2023/01/11. doi:10.1021/acs.molpharmaceut.2c00671. Cited in: Pubmed; PMID 36626167.

Datta-Mannan A, Molitoris BA, Feng Y, Martinez MM, Sandoval RM, Brown RM, Merkel D, Croy JE, Dunn KW. Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody. Drug Metab Dispos. 2023 Mar;51(3):403-412. eng. Epub 2022/12/03. doi:10.1124/dmd.122.001049. Cited in: Pubmed; PMID 36460476.

Dunn KW, Hall AM, Molitoris BA. Editorial: Proceedings of the 2021 Indiana O'Brien Center Microscopy Workshop. Front Physiol. 2022;13:891526. eng. Epub 2022/05/20. doi:10.3389/fphys.2022.891526. Cited in: Pubmed; PMID 35586716.

Dunn KW, Molitoris BA, Dagher PC. The Indiana O'Brien Center for Advanced Renal Microscopic Analysis. Am J Physiol Renal Physiol. 2021 May 1;320(5):F671-f682. eng. Epub 2021/03/09. doi:10.1152/ajprenal.00007.2021. Cited in: Pubmed; PMID 33682441.

Molitoris BA, Sandoval RM, Wagner MC. Intravital Multiphoton Microscopy as a Tool for Studying Renal Physiology, Pathophysiology and Therapeutics. Front Physiol. 2022;13:827280. eng. Epub 2022/04/12. doi:10.3389/fphys.2022.827280. Cited in: Pubmed; PMID 35399274.

Molitoris BA, Sandoval RM, Yadav SPS, Wagner MC. Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications. Physiol Rev. 2022 Oct 1;102(4):1625-1667. eng. Epub 2022/04/06. doi:10.1152/physrev.00014.2021. Cited in: Pubmed; PMID 35378997.

Rosin DL, Hall JP, Zheng S, Huang L, Campos-Bilderback S, Sandoval R, Bree A, Beaumont K, Miller E, Larsen J, Hariri G, Kaila N, Encarnacion IM, Gale JD, van Elsas A, Molitoris BA, Okusa MD. Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors. Front Med (Lausanne). 2022;9:931293. eng. Epub 2022/08/16. doi:10.3389/fmed.2022.931293. Cited in: Pubmed; PMID 35966871.

Wagner MC, Sandoval RM, Campos-Bilderback SB, Molitoris BA. Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes. J Vis Exp. 2022 Mar 4;(181). eng. Epub 2022/03/22. doi:10.3791/63329. Cited in: Pubmed; PMID 35311826.

Wagner MC, Sandoval RM, Yadav SPS, Campos SB, Rhodes GJ, Phillips CL, Molitoris BA. Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity. Kidney360. 2023 Feb 27. eng. Epub 2023/02/28. doi:10.34067/kid.0000000000000094. Cited in: Pubmed; PMID 36848531.


Imaging Methods in Publications

Highlighted Publications

Dunn KW, Molitoris BA, Dagher PC. The Indiana O'Brien Center for Advanced Renal Microscopic Analysis. Am J Physiol Renal Physiol. 2021 May 1;320(5):F671-f682. eng. Epub 2021/03/09. doi:10.1152/ajprenal.00007.2021. Cited in: Pubmed; PMID 33682441.

Thielmann M, Corteville D, Szabo G, Swaminathan M, Lamy A, Lehner LJ, Brown CD, Noiseux N, Atta MG, Squiers EC, Erlich S, Rothenstein D, Molitoris B, Mazer CD. Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study. Circulation. 2021 Oct 5;144(14):1133-1144. eng. Epub 2021/09/04. doi:10.1161/circulationaha.120.053029. Cited in: Pubmed; PMID 34474590.

Yadav SPS, Sandoval RM, Zhao J, Huang Y, Wang E, Kumar S, Campos-Bilderback SB, Rhodes G, Mechref Y, Molitoris BA, Wagner MC. Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance. Am J Physiol Renal Physiol. 2021 Jan 1;320(1):F114-f129. eng. Epub 2020/12/08. doi:10.1152/ajprenal.00428.2020. Cited in: Pubmed; PMID 33283642.

Yu A, Zhao J, Yadav SPS, Molitoris BA, Wagner MC, Mechref Y. Changes in the Expression of Renal Brush Border Membrane N-Glycome in Model Rats with Chronic Kidney Diseases. Biomolecules. 2021 Nov 11;11(11). eng. Epub 2021/11/28. doi:10.3390/biom11111677. Cited in: Pubmed; PMID 34827675.

Yu A, Zhao J, Zhong J, Wang J, Yadav SPS, Molitoris BA, Wagner MC, Mechref Y. Altered O-glycomes of Renal Brush-Border Membrane in Model Rats with Chronic Kidney Diseases. Biomolecules. 2021 Oct 21;11(11). eng. Epub 2021/11/28. doi:10.3390/biom11111560. Cited in: Pubmed; PMID 34827558.

Liu XF, Wei J, Zhou Q, Molitoris BA, Sandoval R, Kobayashi H, Okada R, Nagaya T, Karim B, Butcher D, Pastan I. Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):6086-6091. eng. Epub 2020/03/04. doi:10.1073/pnas.1919038117. Cited in: Pubmed; PMID 32123080.

Otterpohl KL, Busselman BW, Ratnayake I, Hart RG, Hart KR, Evans CM, Phillips CL, Beach JR, Ahrenkiel P, Molitoris BA, Surendran K, Chandrasekar I. Conditional Myh9 and Myh10 inactivation in adult mouse renal epithelium results in progressive kidney disease. JCI Insight. 2020 Nov 5;5(21). eng. Epub 2020/10/02. doi:10.1172/jci.insight.138530. Cited in: Pubmed; PMID 33001861.

Schneider AG, Molitoris BA. Real-time glomerular filtration rate: improving sensitivity, accuracy and prognostic value in acute kidney injury. Curr Opin Crit Care. 2020 Dec;26(6):549-555. eng. Epub 2020/10/02. doi:10.1097/mcc.0000000000000770. Cited in: Pubmed; PMID 33002974.

Ferrell N, Sandoval RM, Molitoris BA, Brakeman P, Roy S, Fissell WH. Application of physiological shear stress to renal tubular epithelial cells. Methods Cell Biol. 2019;153:43-67. eng. Epub 2019/08/10. doi:10.1016/bs.mcb.2019.04.010. Cited in: Pubmed; PMID 31395384.

Molitoris BA. DNA damage response protects against progressive kidney disease. J Clin Invest. 2019 Nov 1;129(11):4574-4575. eng. Epub 2019/10/08. doi:10.1172/jci131171. Cited in: Pubmed; PMID 31589167.

Sandoval RM, Molitoris BA, Palygin O. Fluorescent Imaging and Microscopy for Dynamic Processes in Rats. Methods Mol Biol. 2019;2018:151-175. eng. Epub 2019/06/23. doi:10.1007/978-1-4939-9581-3_7. Cited in: Pubmed; PMID 31228156.

Uchida M, Maier B, Waghwani HK, Selivanovitch E, Pay SL, Avera J, Yun E, Sandoval RM, Molitoris BA, Zollman A, Douglas T, Hato T. The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration. J Clin Invest. 2019 Sep 3;129(9):3941-3951. eng. Epub 2019/08/20. doi:10.1172/jci127511. Cited in: Pubmed; PMID 31424427.

Ferrell, N.; Sandoval, R. M.; Molitoris, B. A.; Brakeman, P.; Roy, S.; Fissell, W. H., Application of physiological shear stress to renal tubular epithelial cells. Methods Cell Biol 2019, 153, 43-67.

Molitoris, B. A., DNA damage response protects against progressive kidney disease. The Journal of clinical investigation 2019, 129 (11), 4574-4575.

Molitoris, B. A., Beyond Biomarkers: Machine Learning in Diagnosing Acute Kidney Injury. Mayo Clinic proceedings 2019, 94 (5), 748-750.

Molitoris, B. A., Rethinking CKD Evaluation: Should We Be Quantifying Basal or Stimulated GFR to Maximize Precision and Sensitivity? American journal of kidney diseases : the official journal of the National Kidney Foundation 2017, 69 (5), 675-683.

Molitoris, B. A.; George, A. G.; Murray, P. T.; Meier, D.; Reilly, E. S.; Barreto, E.; Sandoval, R. M.; Rizk, D. V.; Shaw, A. D.; Peacock, W. F., A Novel Fluorescent Clinical Method to Rapidly Quantify Plasma Volume. Cardiorenal Med 2019, 9 (3), 168-179.

Sandoval, R. M.; Molitoris, B. A.; Palygin, O., Fluorescent Imaging and Microscopy for Dynamic Processes in Rats. Methods in molecular biology (Clifton, N.J.) 2019, 2018, 151-175.

Uchida, M.; Maier, B.; Waghwani, H. K.; Selivanovitch, E.; Pay, S. L.; Avera, J.; Yun, E.; Sandoval, R. M.; Molitoris, B. A.; Zollman, A.; Douglas, T.; Hato, T., The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration. The Journal of clinical investigation 2019, 129 (9), 3941-3951.

Bayliss, G. P.; Cobb, J.; Decker, B.; Hellman, R.; Vasavada, N.; Mackelaite, L.; Shadur, C.; Ilori, T.; Ibrahim, T.; Leight, K.; Hsiao, L. L.; Molitoris, B. A.; Okusa, M. D.; Parker, M. G., Kidney Mentoring and Assessment Program for Students: a guide for engaging medical students in nephrology. Clin Kidney J 2019, 12 (6), 761-766.

Liu, X. F.; Wei, J.; Zhou, Q.; Molitoris, B. A.; Sandoval, R.; Kobayashi, H.; Okada, R.; Nagaya, T.; Karim, B.; Butcher, D.; Pastan, I., Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proc Natl Acad Sci U S A 2020, 117 (11), 6086-6091.

Kolb AL, et al. (2018) Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection. J Am Soc Nephrol. (4):1154-1164

Sandoval RM, Molitoris BA. (2017) Intravital multiphoton microscopy as a tool for studying renal physiology and pathophysiology. Methods. 128:20-32. 

Endres BT, et al. (2017) Intravital imaging of the kidney in a rat model of salt-sensitive hypertension. Am J Physiol Renal Physiol. (2):F163-F173

Hato T, et al.(2017) Two-photon intravital fluorescence lifetime imaging of the kidney reveals cell-type specific metabolic signatures. J Am Soc Nephrol In Process.

Day RN, Tao W, & Dunn KW (2016) A simple approach for measuring FRET in fluorescent biosensors using two-photon microscopy. Nat Protoc 11(11):2066-2080.

Hato T, et al. (2016) Novel application of complimentary imaging techniques to examine in vivo glucose metabolism in the kidney. Am J Physiol Renal Physiol:ajprenal 00535 02015.

Wagner MC, et al. (2016) Proximal Tubules Have the Capacity to Regulate Uptake of Albumin. J Am Soc Nephrol 27(2):482-494.

Wagner MC, et al. (2016) Mechanism of increased clearance of glycated albumin by proximal tubule cells. Am J Physiol Renal Physiol 310(10):F1089-1102.

Tao W, et al. (2015) A practical method for monitoring FRET-based biosensors in living animals using two-photon microscopy. Am J Physiol Cell Physiol 309(11):C724-735.

El-Achkar TM & Dagher PC (2015) Tubular cross talk in acute kidney injury: a story of sense and sensibility. Am J Physiol Renal Physiol 308(12):F1317-1323.

Hato T & Dagher PC (2015) How the Innate Immune System Senses Trouble and Causes Trouble. Clin J Am Soc Nephrol 10(8):1459-1469.

Hato T, et al. (2015) The macrophage mediates the renoprotective effects of endotoxin preconditioning. J Am Soc Nephrol 26(6):1347-1362.

Hato T, Sandoval R, & Dagher PC (2015) The caspase 3 sensor Phiphilux G2D2 is activated non-specifically in S1 renal proximal tubules. Intravital 4(2).

Ferrell N, et al. (2015) Shear stress is normalized in glomerular capillaries following (5/6) nephrectomy. Am J Physiol Renal Physiol 308(6):F588-593.

Ryan JC, Dunn KW, & Decker BS (2014) Effects of chronic kidney disease on liver transport: quantitative intravital microscopy of fluorescein transport in the rat liver. Am J Physiol Regul Integr Comp Physiol 307(12):R1488-1492.

Sandoval RM, Wang E, & Molitoris BA (2014) Finding the bottom and using it: Offsets and sensitivity in the detection of low intensity values in vivo with 2-photon microscopy. Intravital 2(1).

Dickson LE, Wagner MC, Sandoval RM, & Molitoris BA (2014) The proximal tubule and albuminuria: really! J Am Soc Nephrol 25(3):443-453.

Carrisoza-Gaytan R, et al. (2014) Effects of biomechanical forces on signaling in the cortical collecting duct (CCD). Am J Physiol Renal Physiol 307(2):F195-204.

Molitoris BA (2014) Therapeutic translation in acute kidney injury: the epithelial/endothelial axis. J Clin Invest 124(6):2355-2363.

Hall AM & Molitoris BA (2014) Dynamic multiphoton microscopy: focusing light on acute kidney injury. Physiology (Bethesda) 29(5):334-342.

Hato T, El-Achkar TM, & Dagher PC (2013) Sisters in arms: myeloid and tubular epithelial cells shape renal innate immunity. Am J Physiol Renal Physiol 304(10):F1243-1251.

Hall AM, Rhodes GJ, Sandoval RM, Corridon PR, & Molitoris BA (2013) In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury. Kidney Int 83(1):72-83.

Sandoval RM & Molitoris BA (2013) Quantifying glomerular permeability of fluorescent macromolecules using 2-photon microscopy in Munich Wistar rats. J Vis Exp (74).

Molitoris BA & Sandoval RM (2009) Techniques to study nephron function: microscopy and imaging. Pflugers Arch 458(1):203-209.

Dunn KW, Sutton TA, & Sandoval RM (2012) Live-animal imaging of renal function by multiphoton microscopy. Curr Protoc Cytom Chapter 14:Unit12 19.

Babbey CM, et al. (2012) Quantitative intravital microscopy of hepatic transport. Intravital 1:1-10.

Wang E, et al. (2012) A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals. Kidney Int 81(1):112-117.

Sandoval RM, et al. (2012) Multiple factors influence glomerular albumin permeability in rats. J Am Soc Nephrol 23(3):447-457.

Imamura R, et al. (2012) A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney. Clin Exp Nephrol 16(6):852-862.

Saleh MA, et al. (2012) Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat. Life Sci 91(13-14):634-637.

Thompson JD, et al. (2012) Toxicological and pharmacokinetic properties of chemically modified siRNAs targeting p53 RNA following intravenous administration. Nucleic Acid Ther 22(4):255-264.

Choong FX, Sandoval RM, Molitoris BA, & Richter-Dahlfors A (2012) Multiphoton microscopy applied for real-time intravital imaging of bacterial infections in vivo. Methods Enzymol 506:35-61.

Presson RG, Jr., et al. (2011) Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact. Am J Pathol 179(1):75-82.

Kalakeche R, et al. (2011) Endotoxin uptake b     by S1 proximal tubular segment causes oxidative stress in the downstream S2 segment. J Am Soc Nephrol 22(8):1505-1516.

Basile DP, et al. (2011) Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury. Am J Physiol Renal Physiol 300(3):F721-733.

Melican K, et al. (2011) Uropathogenic Escherichia coli P and Type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction. PLoS Pathog 7(2):e1001298.

Sharfuddin AA & Molitoris BA (2011) Pathophysiology of ischemic acute kidney injury. Nat Rev Nephrol 7(4):189-200.

Molitoris BA & Sandoval RM (2011) Kidney endothelial dysfunction: ischemia, localized infections and sepsis. Contrib Nephrol 174:108-118.

Kamocka MM, et al. (2010) Two-photon intravital imaging of thrombus development. J Biomed Opt 15(1):016020.

Wang E, Sandoval RM, Campos SB, & Molitoris BA (2010) Rapid diagnosis and quantification of acute kidney injury using fluorescent ratio-metric determination of glomerular filtration rate in the rat. Am J Physiol Renal Physiol 299(5):F1048-1055.

Imamura R, et al. (2010) Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models. Cell Transplant 19(12):1659-1670.

Molitoris BA & Sandoval RM (2010) Multiphoton imaging techniques in acute kidney injury. Contrib Nephrol 165:46-53.

Campos SB, et al. (2009) Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation. Am J Physiol Renal Physiol 296(3):F487-495.

Sharfuddin AA, et al. (2009) Soluble thrombomodulin protects ischemic kidneys. J Am Soc Nephrol 20(3):524-534.

Russo LM, et al. (2009) Impaired tubular uptake explains albuminuria in early diabetic nephropathy. J Am Soc Nephrol 20(3):489-494.

Molitoris BA, et al. (2009) siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury. J Am Soc Nephrol 20(8):1754-1764.

Gupta A, Williams MD, Macias WL, Molitoris BA, & Grinnell BW (2009) Activated protein C and acute kidney injury: Selective targeting of PAR-1. Curr Drug Targets 10(12):1212-1226.

Dunn KW & Sutton TA (2008) Functional studies in living animals using multiphoton microscopy. ILAR J 49(1):66-77.

Melican K, et al. (2008) Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis. Cell Microbiol 10(10):1987-1998.

Wagner MC, et al. (2008) Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1. J Biol Chem 283(51):35579-35589.

Sandoval RM & Molitoris BA (2008) Quantifying endocytosis in vivo using intravital two-photon microscopy. Methods Mol Biol 440:389-402.

Sharfuddin AA, Sandoval RM, & Molitoris BA (2008) Imaging techniques in acute kidney injury. Nephron Clin Pract 109(4):c198-204.

El-Achkar TM, Plotkin Z, Marcic B, & Dagher PC (2007) Sepsis induces an increase in thick ascending limb Cox-2 that is TLR4 dependent. Am J Physiol Renal Physiol 293(4):F1187-1196.

Mansson LE, et al. (2007) Real-time studies of the progression of bacterial infections and immediate tissue responses in live animals. Cell Microbiol 9(2):413-424.

Horbelt M, et al. (2007) Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy. Kidney Int 72(4):422-429.

Gupta A, et al. (2007) Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2. Am J Physiol Renal Physiol 293(1):F245-254.

Yu W, Sandoval RM, & Molitoris BA (2007) Rapid determination of renal filtration function using an optical ratiometric imaging approach. Am J Physiol Renal Physiol 292(6):F1873-1880.

Russo LM, et al. (2007) The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int 71(6):504-513.

Ashworth SL, Sandoval RM, Tanner GA, & Molitoris BA (2007) Two-photon microscopy: visualization of kidney dynamics. Kidney Int 72(4):416-421.

Molitoris BA & Sandoval RM (2007) Quantifying dynamic kidney processes utilizing multi-photon microscopy. Contrib Nephrol 156:227-235.

Mansson LE, Melican K, Molitoris BA, & Richter-Dahlfors A (2007) Progression of bacterial infections studied in real time--novel perspectives provided by multiphoton microscopy. Cell Microbiol 9(10):2334-2343.

Wagner MC, Molnar EE, Molitoris BA, & Goebl MG (2006) Loss of the homotypic fusion and vacuole protein sorting or golgi-associated retrograde protein vesicle tethering complexes results in gentamicin sensitivity in the yeast Saccharomyces cerevisiae. Antimicrob Agents Chemother 50(2):587-595.

Suurna MV, et al. (2006) Cofilin mediates ATP depletion-induced endothelial cell actin alterations. Am J Physiol Renal Physiol 290(6):F1398-1407.

Sandoval RM, et al. (2006) A non-nephrotoxic gentamicin congener that retains antimicrobial efficacy. J Am Soc Nephrol 17(10):2697-2705.

Molitoris BA & Sandoval RM (2006) Pharmacophotonics: utilizing multi-photon microscopy to quantify drug delivery and intracellular trafficking in the kidney. Adv Drug Deliv Rev 58(7):809-823.

Herget-Rosenthal S & Molitoris BA (2006) Advances in imaging the kidney and cellular processes. Nephron Exp Nephrol 103(2):e31-32.

Molitoris BA & Sandoval RM (2005) Intravital multiphoton microscopy of dynamic renal processes. Am J Physiol Renal Physiol 288(6):F1084-1089.

Yu W, Sandoval RM, & Molitoris BA (2005) Quantitative intravital microscopy using a Generalized Polarity concept for kidney studies. Am J Physiol Cell Physiol 289(5):C1197-1208.

Tanner GA, Sandoval RM, Molitoris BA, Bamburg JR, & Ashworth SL (2005) Micropuncture gene delivery and intravital two-photon visualization of protein expression in rat kidney. Am J Physiol Renal Physiol 289(3):F638-643.

Tanner GA, Sandoval RM, & Dunn KW (2004) Two-photon in vivo microscopy of sulfonefluorescein secretion in normal and cystic rat kidneys. Am J Physiol Renal Physiol 286(1):F152-160.

Atkinson SJ, Hosford MA, & Molitoris BA (2004) Mechanism of actin polymerization in cellular ATP depletion. J Biol Chem 279(7):5194-5199.

Sandoval RM & Molitoris BA (2003) Gentamicin traffics retrograde through the secretory pathway and is released in the cytosol via the endoplasmic reticulum. Am J Physiol Renal Physiol 286(4):F617-624.

Ashworth SL, et al. (2004) Renal ischemia induces tropomyosin dissociation-destabilizing microvilli microfilaments. Am J Physiol Renal Physiol 286(5):F988-996.

Sandoval RM, Kennedy MD, Low PS, & Molitoris BA (2004) Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy. Am J Physiol Cell Physiol 287(2):C517-526.

Molitoris BA & Sutton TA (2004) Endothelial injury and dysfunction: role in the extension phase of acute renal failure. Kidney Int 66(2):496-499.

Kelly KJ, Sandoval RM, Dunn KW, Molitoris BA, & Dagher PC (2003) A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis. Am J Physiol Cell Physiol 284(5):C1309-1318.

Dunn KW, Sandoval RM, & Molitoris BA (2003) Intravital imaging of the kidney using multiparameter multiphoton microscopy. Nephron Exp Nephrol 94(1):e7-11.

Ashworth SL, et al. (2003) ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion. Am J Physiol Renal Physiol 284(4):F852-862.

Sutton TA, et al. (2003) Injury of the renal microvascular endothelium alters barrier function after ischemia. Am J Physiol Renal Physiol 285(2):F191-198.

Dunn KW, et al. (2002) Functional studies of the kidney of living animals using multicolor two-photon microscopy. Am J Physiol Cell Physiol 283(3):C905-916.