Pediatrics

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Allergy/Immunology Fellowship

The IU School of Medicine Allergy/ Immunology Fellowship is an ACGME-accredited the two-year program that prepares physicians in the expert care and management of allergy and immunology issues for both children and adults. Allergy/Immunology fellows acquire a wide range of clinical and research experiences and are prepared for academic careers as a physician-scientist or clinician-educator. The fellowship produces specialists who excel in patient care skills and diagnostic acumen and who know how to analyze and apply research. On completion of the fellowship, the physician is eligible to sit for the Board Certification Exam of the American Board of Allergy and Immunology.

The Allergy/Immunology Fellowship program, accredited in 2017, is offered by IU School of Medicine Department of Pediatrics Division of Pediatric Pulmonology and Sleep Medicine. Fellows train at Riley Hospital for Children at IU Health in Indianapolis.

Clinical Experience

Fellows rotate through clinics in Indianapolis, Carmel and Lafayette, Indiana, with diverse training opportunities. IU School of Medicine allergy faculty participate in multi-disciplinary clinics at Riley Hospital for Children, such as the Gastrointestinal Eosinophilic Digestive Disease Clinic and High-Risk Asthma Clinic. Faculty are also involved in the Indiana Joint Asthma Coalition, the Indiana Allergy and Immunology Society, committees of the American Academy of Allergy, Asthma, and Immunology (AAAAI), and the Food Allergy Research and Education (FARE) Clinical Network.

Division research and clinical programs are growing in both scope and recognition. Riley Hospital is a designated Center of Clinical Excellence by the Food Allergy Research and Education Network. Current research includes projects in peanut allergy, airway microbiome in relation to airway inflammation, local pollen changes, and immune deficiency assessment. Kirsten Kloepfer, MD, received the AAAAI Faculty Development Award in 2017. More than fifteen fellowship programs are available through IU School of Medicine at Riley Hospital, providing a broad range of mentors and educational opportunities.

Research

Fellows are expected to act as a principal investigator in at least one research project in which he/she designs and implements a study, analyzes the data, presents the findings at regional and/or national meetings, and prepares a manuscript draft for publication. Numerous opportunities are available for fellows to identify research topics with faculty engaged in basic science and clinical research.

Food Allergy Research Programs

IU School of Medicine allergists are actively involved in research for emerging treatments for food allergy, including both oral and “patch” (transcutaneous) immunotherapy. Outcomes of Food Challenges are monitored, and these studies have been published and presented at national meetings.

Allergy/Immunology faculty work with the Food Allergy Research and Education (FARE) Clinical Network, and Riley Hospital for Children holds a Center of Clinical Excellence designation. Through this affiliation, IU School of Medicine faculty have access to clinical trials and innovative new research for the treatment of food allergies. Collaborating with the FARE Clinical Network also provides access to the latest evidence-based, advanced treatments and standards for pediatric food allergies.

The Division of Pediatric Pulmonology, Allergy and Sleep Medicine at IU School of Medicine houses one of the largest registries of children with peanut allergy. This database enables physician scientists to detect trends and patterns among children with peanut allergy, which could lead to new opportunities for treatment. The Division is also establishing a comprehensive food allergy registry.

Kirsten Kloepfer, MD, is pursuing a longitudinal study following a group of neonates recruited at birth. To study the relationship between the upper airway microbiome and both airway inflammation and airway function Dr. Kloepfer is using: 1) advanced methods for bacterial detection (16S rRNA sequencing); 2) cytokine analysis to measure cellular proteins linked with inflammation; and 3) infant airway function testing. Dr Kloepfer received the AAAAI Faculty Development Award in 2017.

Basic science research is conducted at the Herman B Wells Center for Pediatric Research, located in a facility attached to Riley Hospital for Children at IU Health (Indianapolis). Investigators study the initiation, pathogenesis and progression of allergic diseases in order to identify better ways to treat or prevent allergic symptoms. Research spans many areas from examining the regulation of genes important for the development of T cells involved in allergic inflammation, to the biology of cytokines and other factors that promote allergic disease and examining lung development and function and how changes contribute to lung reactivity to allergens.

The allergy program at Riley Hospital has published research in recent years comparing local and longitudinal pollen counts that have been published and presented nationally.