6469-Messina, Frank

Frank C. Messina, MD

Associate Professor of Clinical Emergency Medicine

Medical Director, Eskenazi Hospital Transition Support Department

Medical Director, Eskenazi Clinical Decision Unit

Eskenazi Health 720 Eskenazi Avenue
FOB 3rd Fl. Department of Emergency Medicine
Indianapolis, IN 46202
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Frank is a 1983 graduate of Columbia University (President Obama’s classmate) and graduated from the Mount Sinai School of Medicine (now Icahn) of the City University of New York in 1987. He completed an Internal Medicine residency at Thomas Jefferson University in Philadelphia. He subsequently did a fellowship in General Internal Medicine/Primary Care Education/Clinical Research Methods at Indiana University School of Medicine. He is ABIM and ABEM certified.

Frank has been on the faculty since 1990. He is currently the Medical Director of the Eskenazi Hospital Transition Support Department, and the Medical Director of the Eskenazi Emergency Department’s Clinical Decision (Observation) Unit. He has been an associate medical director of the emergency department at Eskenazi Hospital (now Eskenazi Hospital) where he still works clinically. His clinical/administrative interests overlap around Observation Medicine, Utilization Review and health care financing and revenue cycle.  He continues to collaborate with Department of Geriatrics members on research pertninent to older adults in the ED including delirium and dementia.

Frank has been recognized for teaching excellence with several awards, and was the recipient of a $80,000 Clarian Values Fund educational grant, several grants to sponsor "mini-medical schools" for the local public, and grants to support the cadaver training labs. He has been a co-host for the Public Radio show “Sound Medicine” which is also podcasted.

Frank is a reviewer for the American Journal of Emergency Medicine and for the MedEdPortal of the Association of American Medical Colleges for which he was honored in 2010-2011 as one of its top 20 reviewers for comprehensiveness and quality.

When Frank is not helping his 21 year old and 20 year old children or working, he rides his bike to work, sometimes along with his wife of 29 years who is a retired manager at Eli Lilly and Company also in downtown Indy.

Key Publications

Messina FC, Cooper D, Huffman G, Wilbur L, Bartkus E. A Human Cadaver Fascial Compartment Pressure Measurement Model. Journal of Emergency Medicine, 45:e127–e131, 2013. PMID: 23845521.


Messina FC, McDaniel MA, Trammel AC, Ervin DR, Kozak MA, Weaver CS. Improving specialty care follow-up after an ED visit using a unique referral system. American Journal of Emergency Medicine 31:1495-1500, 2013. PMID: 24035046.


LaMantia MA, Messina FC, Hobgood CD, Miller DK. Screening for delirium in the emergency department: a systematic review. Ann Emerg Med. 2014 May;63(5):551-560.e2. doi: 10.1016/j.annemergmed.2013.11.010. Epub 2013 Dec 16. Review. PubMed PMID: 24355431.


LaMantia MA, Boustani MA, Jhanji S, Maina M, Nazir A, Messina FC, Frame A, Alder C, Chodosh J. Redesigning acute care for cognitively impaired older adults: Optimizing health care services Dementia (London). 2016 Sep;15(5):913-30. doi: 10.1177/1471301214547089. Epub 2014 Aug 15. PMID: 25128821


LaMantia, Messina, FC, McGuire, SM ; Jhanji, SS Maina, M; Nazir, A Hobgood, C; Miller, DK; Emergency Medical Service, Nursing, and Physician Providers’ Perspectives on Delirium Identification and Management; Dementia (London). 2017 Apr;16(3):329-343. doi: 10.1177/1471301215591896. Epub 2016 Jul 26. PMID:26112165


LaMantia MA, Stump TE, Messina FC, Miller DK, Callahan CM. Emergency Department Use Among Older Adults With Dementia. Alzheimer Dis Assoc Disord. 2016 Jan-Mar;30(1):35-40. doi: 10.1097/WAD.0000000000000118. PMID:26523710


Lamantia Michael, Lane Kathleen, Tu Wanzhu, Carnahan Jennifer, Messina Frank, Unroe Kathleen (2016). Patterns of Emergency Department Use Among Long-Stay Nursing Home Residents with Differing Levels of Dementia Severity. Journal of the American Medical Directors Association, 17(6), 541-546.


Sher SJ, Aftab W, Moorthi RN, Moe SM, Weaver CS, Messina FC, Martinez-Hoover NM, Anderson MD, Eadon MT. Healthcare outcomes in undocumented immigrants undergoing two emergency dialysis approaches. Clin Nephrol. 2017 Oct;88(10):181-192. doi: 10.5414/CN109137. PMID: 28818188

Fisher-Trotter H, Collins S, Danagoulian S, Hunter B, Li X, Levy P, Messina F, Pressler S, Pang P.  Design and Rationale of a Randomized Trial: Using Short Stay Units Instead of Routine Admission to Improve Patient Centered Health Outcomes for Acute Heart Failure Patients (SSU-AHF). Contemp Clin Trials. 2018 Sep;72:137-145. doi: 10.1016/j.cct.2018.08.003. Epub 2018 Aug 17

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