63019-Davis, Jessica L.

Jessica L. Davis, MD

Centennial Professor of Pathology & Laboratory Medicine

Professor of Clinical Pathology & Laboratory Medicine

Director of Surgical Pathology

CP 4010
350 West 11st Street
Indianapolis, IN 46202
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Jessica L. Davis, M.D., is the Centennial Professor of Pathology and Laboratory Medicine and serves as the Vice Chair of Anatomic Pathology at Indiana University School of Medicine/Health. Dr. Davis received her medical degree from Oregon Health & Science University (OHSU) and subsequently completed training in anatomic and clinical pathology at the University of California San Francisco (UCSF). While at UCSF, she also completed a surgical pathology fellowship with an emphasis on bone and soft tissue pathology. Dr. Davis then joined Seattle Children’s Hospital and the University of Washington for a pediatric pathology fellowship before returning to UCSF as Assistant Professor. She was later recruited to OHSU to lead the pediatric and bone and soft tissue pathology divisions and served as their Director of Surgical Pathology.  She is thrilled to now be at Indiana University to serve amongst the fabulous pathology group at IU!  

In addition to her clinical and administrative responsibilities at IU, Dr. Davis teaches residents and fellows in pathology and is actively engaged in clinical and translational research on soft tissue tumors. Nationally, Dr. Davis serves the Children’s Oncology Group (COG) as a central pathology reviewer for non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) and bone sarcomas and is on the steering committee for bone tumors. Dr. Davis is an active member of the United States and Canadian Academy of Pathology (USCAP) and the Society for Pediatric Pathology (SPP), where she serves on committees and reviews scientific abstracts. She is the pediatric representative to the College of American Pathologists (CAP) Cancer Committee, which helped propel her interest into large scale systems/data standardization and data harmonization efforts.  These efforts include collaborative work through the NIH/NCI sponsored initiatives CancerPathCHART, SEER ClinCORE, and efforts with the Childhood Cancer Data Initiative in providing pathology support in sarcoma and pediatrics for data harmonization and review of pathology slides.  Dr. Davis is a founding member of and serves as Vice President for a non-profit organization focused on collaborative research on pediatric sarcomas (SPPRITEs; Sarcoma Pediatric Pathology Research Interests). She has written more than 60 peer reviewed publications, review articles and book chapters, the latter of which include invited contributions to the 5th editions of the World Health Organization Classifications of Bone and Soft Tissue Tumours, Paediatric Tumours, and Skin Tumors. She is a bone and soft tissue section editor for the journal Diagnostic Pathology and serves as an invited reviewer for other pathology journals. She has been an invited lecturer at numerous regional, national and international meetings and conferences.  

Key Publications

Davis JL, Lockwood CM, Stohr B, Boecking C, Al-Ibraheemi A, DuBois SG, Vargas SO, Black JO, Cox MC, Luquette M, Turpin B, Szabo S, Laetsch TW, Albert CM, Parham DM, Hawkins DS, Rudzinski ER. Expanding the Spectrum of Pediatric NTRK-rearranged Mesenchymal Tumors. Am J Surg Pathol. 2019 Apr;43(4):435-445. doi: 10.1097/PAS.0000000000001203. PubMed PMID: 30585824.

Davis JL, Vargas SO, Rudzinski ER, López Marti JM, Janeway K, Forrest S, Winsnes K, Pinto N, Yang SE, VanSandt M, Boyd TK, Corless CL, Liu YJ, Surrey LF, Harris MH, Church A, Al-Ibraheemi A. Recurrent RET gene fusions in paediatric spindle mesenchymal neoplasms. Histopathology. 2020 Jun;76(7):1032-1041. doi: 10.1111/his.14082. Epub 2020 May 15. PubMed PMID: 31994201.

Penning AJ, Al-Ibraheemi A, Michal M, Larsen BT, Cho SJ, Lockwood CM, Paulson VA, Liu YJ, Plank L, Fritchie K, Beadling C, Neff TL, Corless CL, Rudzinski ER, Davis JL. Novel BRAF gene fusions and activating point mutations in spindle cell sarcomas with histologic overlap with infantile fibrosarcoma. Mod Pathol. 2021 Aug;34(8):1530-1540. doi: 10.1038/s41379-021-00806-w. Epub 2021 Apr 13. PubMed PMID: 33850302.

Tan SY, Al-Ibraheemi A, Ahrens WA, Oesterheld JE, Fanburg-Smith JC, Liu YJ, Spunt SL, Rudzinski ER, Coffin C, Davis JL. ALK rearrangements in infantile fibrosarcoma-like spindle cell tumours of soft tissue and kidney. Histopathology. 2022 Mar;80(4):698-707. doi: 10.1111/his.14603. Epub 2022 Jan 2. PubMed PMID: 34843129.

Davis JL, Al-Ibraheemi A, Rudzinski ER, Surrey LF. Mesenchymal neoplasms with NTRK and other kinase gene alterations. Histopathology. 2022 Jan;80(1):4-18. doi: 10.1111/his.14443. Review. PubMed PMID: 34958503.

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