William R. Clark, MD
Adjunct Clinical Professor of Medicine
Adjunct Clinical Professor of Anatomy, Cell Biology & Physiology
Assistant Professor of Medicine
- Address
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FS 5100
MEDL
IN
Indianapolis, IN - PubMed:
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| Year | Degree | Institution |
|---|---|---|
| 1986 | MD | Indiana University |
| 1982 | BS | Purdue University |
The goal of my research is the development of an improved understanding ofextracorporeal solute removal in patients with end stage renal disease. In thelaboratory, the mass transfer characterization of plasma protein removal by highpermeability dialysis membranes is the primary pursuit with membrane adsorption mostextensively investigated. In collaboration with Dr. Meri Kay Scott and Dr. BruceMueller of the Purdue School of Pharmacy, I am now investigating the effect of dialyzerreprocessing agents on solute removal.
My clinical research is focused on quantification of solute removal during hemodialysis(HD). This includes comparing the various methods used to assess HD adequacy,particularly with regard to the manner in which these methods differ in high-flux HD.Another initiative is the quantification of solute removal over a wide molecular weightspectrum for HD regimens of varying duration and frequency, including daily HD. Thislatter type of quantification is performed with computer modeling.
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