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P. Artur Plett, PhD
P. Artur Plett, PhD
Assistant Scientist in Medicine
Cancer Research Institute, Room 202
1044 W. Walnut St.
Indianapolis, IN 46202-5254
Titles & Appointments
Assistant Scientist in Medicine
MCP Hahnemann University
Warren Wilson College
Prostaglandin E<sub>2</sub> Enhances Aged Hematopoietic Stem Cell Function.
Patterson AM; Plett PA; Sampson CH; Simpson E; Liu Y; Pelus LM; Orschell CM; Stem cell reviews and reports 2021 May 11
Optimizing and Profiling Prostaglandin E2 as a Medical Countermeasure for the Hematopoietic Acute Radiation Syndrome.
Patterson AM; Wu T; Chua HL; Sampson CH; Fisher A; Singh P; Guise TA; Feng H; Muldoon J; Wright L; Plett PA; Pelus LM; Orschell CM; Radiation research 2021 Feb 1
Establishing Pediatric Mouse Models of the Hematopoietic Acute Radiation Syndrome and the Delayed Effects of Acute Radiation Exposure.
Patterson AM; Sellamuthu R; Plett PA; Sampson CH; Chua HL; Fisher A; Vemula S; Feng H; Katz BP; Tudor G; Miller SJ; MacVittie TJ; Booth C; Orschell CM; Radiation research 2021 Apr 1
Immune Reconstitution and Thymic Involution in the Acute and Delayed Hematopoietic Radiation Syndromes.
Wu T; Plett PA; Chua HL; Jacobsen M; Sandusky GE; MacVittie TJ; Orschell CM; Health physics 2020 Nov
Development of a Model of the Acute and Delayed Effects of High Dose Radiation Exposure in Jackson Diversity Outbred Mice; Comparison to Inbred C57BL/6 Mice.
Patterson AM; Plett PA; Chua HL; Sampson CH; Fisher A; Feng H; Unthank JL; Miller SJ; Katz BP; MacVittie TJ; Orschell CM; Health physics 2020 Nov
A Single Radioprotective Dose of Prostaglandin E<sub>2</sub> Blocks Irradiation-Induced Apoptotic Signaling and Early Cycling of Hematopoietic Stem Cells.
Patterson AM; Liu L; Sampson CH; Plett PA; Li H; Singh P; Mohammad KS; Hoggatt J; Capitano ML; Orschell CM; Pelus LM; Stem cell reports 2020 Jul 30
Cardiac and Renal Delayed Effects of Acute Radiation Exposure: Organ Differences in Vasculopathy, Inflammation, Senescence and Oxidative Balance.
Unthank JL; Ortiz M; Trivedi H; Pelus LM; Sampson CH; Sellamuthu R; Fisher A; Chua HL; Plett A; Orschell CM; Cohen EP; Miller SJ; Radiation research 2019 Mar 22
Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass.
Maupin KA; Himes ER; Plett AP; Chua HL; Singh P; Ghosh J; Mohamad SF; Abeysekera I; Fisher A; Sampson C; Hong JM; Childress P; Alvarez M; Srour EF; Bruzzaniti A; Pelus LM; Orschell CM; Kacena MA; Bone 2019 Jul 9
Lifelong Residual bone Marrow Damage in Murine Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS): A Compilation of Studies Comprising the Indiana University Experience.
Chua HL; Plett PA; Fisher A; Sampson CH; Vemula S; Feng H; Sellamuthu R; Wu T; MacVittie TJ; Orschell CM; Health physics 2019 Apr
An oral Hemokine<sup>TM</sup>, a-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo.
Faller DV; Castaneda SA; Zhou D; Vedamony M; Newburger PE; White GL; Kosanke S; Plett PA; Orschell CM; Boosalis MS; Perrine SP; Blood cells, molecules & diseases 2016 Oct 31
The H-ARS Dose Response Relationship (DRR): Validation and Variables.
Plett PA; Sampson CH; Chua HL; Jackson W; Vemula S; Sellamuthu R; Fisher A; Feng H; Wu T; MacVittie TJ; Orschell CM; 2015 Nov
Delayed Effects of Acute Radiation Exposure in a Murine Model of the H-ARS: Multiple-Organ Injury Consequent to <10 Gy Total Body Irradiation.
Unthank JL; Miller SJ; Quickery AK; Ferguson EL; Wang M; Sampson CH; Chua HL; DiStasi MR; Feng H; Fisher A; Katz BP; Plett PA; Sandusky GE; Sellamuthu R; Vemula S; Cohen EP; MacVittie TJ; Orschell CM; 2015 Nov
Survival efficacy of the PEGylated G-CSFs Maxy-G34 and neulasta in a mouse model of lethal H-ARS, and residual bone marrow damage in treated survivors.
Chua HL; Plett PA; Sampson CH; Katz BP; Carnathan GW; MacVittie TJ; Lenden K; Orschell CM; Health physics 2014 Jan
PEGylated G-CSF (BBT-015), GM-CSF (BBT-007), and IL-11 (BBT-059) analogs enhance survival and hematopoietic cell recovery in a mouse model of the hematopoietic syndrome of the acute radiation syndrome.
Plett PA; Chua HL; Sampson CH; Katz BP; Fam CM; Anderson LJ; Cox GN; Orschell CM; Health physics 2014 Jan
Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation.
Cheng YH; Hooker RA; Nguyen K; Gerard-O'Riley R; Waning DL; Chitteti BR; Meijome TE; Chua HL; Plett AP; Orschell CM; Srour EF; Mayo LD; Pavalko FM; Bruzzaniti A; Kacena MA; 2013 Jun
Long-term hematopoietic stem cell damage in a murine model of the hematopoietic syndrome of the acute radiation syndrome.
Chua HL; Plett PA; Sampson CH; Joshi M; Tabbey R; Katz BP; MacVittie TJ; Orschell CM; Health physics 2012 Oct
Establishing a murine model of the hematopoietic syndrome of the acute radiation syndrome.
Plett PA; Sampson CH; Chua HL; Joshi M; Booth C; Gough A; Johnson CS; Katz BP; Farese AM; Parker J; MacVittie TJ; Orschell CM; Health physics 2012 Oct
Recovery from hematopoietic injury by modulating prostaglandin E(2) signaling post-irradiation.
Hoggatt J; Singh P; Stilger KN; Plett PA; Sampson CH; Chua HL; Orschell CM; Pelus LM; Blood cells, molecules & diseases 2012 Nov 30
Thrice weekly azacitidine does not improve hematological responses in lower-risk myelodysplastic syndromes: a study of the Hoosier Oncology Group.
Sayar H; Chan RJ; Orschell CM; Chan EM; Yu Z; Hood D; Plett A; Yang Z; Hui CL; Nabinger SC; Kohlbacher KJ; West ES; Walter A; Sampson C; Wu J; Cripe LD; 2011 Mar 21
Endothelial-monocyte-activating polypeptide II induces migration of endothelial progenitor cells via the chemokine receptor CXCR3.
Hou Y; Plett PA; Ingram DA; Rajashekhar G; Orschell CM; Yoder MC; March KL; Clauss M; Experimental hematology 2006 Aug
Cord blood stem and progenitor cells.
Broxmeyer HE; Srour E; Orschell C; Ingram DA; Cooper S; Plett PA; Mead LE; Yoder MC; Methods in enzymology 2006
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.
Broxmeyer HE; Orschell CM; Clapp DW; Hangoc G; Cooper S; Plett PA; Liles WC; Li X; Graham-Evans B; Campbell TB; Calandra G; Bridger G; Dale DC; Srour EF; The Journal of experimental medicine 2005 Apr 18
A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint.
Freie BW; Ciccone SL; Li X; Plett PA; Orschell CM; Srour EF; Hanenberg H; Schindler D; Lee SH; Clapp DW; 2004 Sep 17
Modulation of in vitro proliferation kinetics and primitive hematopoietic potential of individual human CD34+CD38-/lo cells in G0.
Srour EF; Tong X; Sung KW; Plett PA; Rice S; Daggy J; Yiannoutsos CT; Abonour R; Orschell CM; 2004 Dec 21
Impact of modeled microgravity on migration, differentiation, and cell cycle control of primitive human hematopoietic progenitor cells.
Plett PA; Abonour R; Frankovitz SM; Orschell CM; 2004 Aug
Distribution of marrow repopulating cells between bone marrow and spleen early after transplantation.
Plett PA; Frankovitz SM; Orschell CM; 2003 May 29
Fanconi anemia type C-deficient hematopoietic stem/progenitor cells exhibit aberrant cell cycle control.
Li X; Plett PA; Yang Y; Hong P; Freie B; Srour EF; Orschell CM; Clapp DW; Haneline LS; 2003 May 22
Treatment of circulating CD34(+) cells with SDF-1alpha or anti-CXCR4 antibody enhances migration and NOD/SCID repopulating potential.
Plett PA; Frankovitz SM; Wolber FM; Abonour R; Orschell-Traycoff CM; 2002 Sep
In vivo trafficking, cell cycle activity, and engraftment potential of phenotypically defined primitive hematopoietic cells after transplantation into irradiated or nonirradiated recipients.
Plett PA; Frankovitz SM; Orschell-Traycoff CM; 2002 Nov 15
Homing efficiency, cell cycle kinetics, and survival of quiescent and cycling human CD34(+) cells transplanted into conditioned NOD/SCID recipients.
Jetmore A; Plett PA; Tong X; Wolber FM; Breese R; Abonour R; Orschell-Traycoff CM; Srour EF; 2002 Mar 1
Homing, cell cycle kinetics and fate of transplanted hematopoietic stem cells.
Srour EF; Jetmore A; Wolber FM; Plett PA; Abonour R; Yoder MC; Orschell-Traycoff CM; 2001 Nov
Proliferation of human hematopoietic bone marrow cells in simulated microgravity.
Plett PA; Frankovitz SM; Abonour R; Orschell-Traycoff CM; 2001 Feb
Age-related changes in interferon-alpha/beta receptor expression, binding, and induction of apoptosis in natural killer cells from C57BL/6 mice.
Plett PA; Gardner EM; Murasko DM; 2000 Sep 29
Genetic differences in the age-associated decrease in inducibility of natural killer cells by interferon-alpha/beta.
Plett A; Murasko DM; 2000 Jan 10
Cloning of the haemocin locus of Haemophilus influenzae type b and assessment of the role of haemocin in virulence.
Murley YM; Edlind TD; Plett PA; LiPuma JJ; 1998 Sep
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