Howard C. Masuoka, MD, PhD

Faculty

Howard C. Masuoka, MD, PhD

Assistant Professor of Clinical Medicine

Phone (317) 944-0980

Address

Regenstrief Health Center, Room 4100
1050 Wishard Blvd.

Indianapolis , IN 46202-2859

Titles & Appointments

Assistant Professor of Clinical Medicine
Adjunct Assistant Professor of Anatomy, Cell Biology & Physiology

Education

2011 FEL Mayo Clinic College of Medicine, Rochester, MN

2010 FEL Mayo Clinic College of Medicine, Rochester, MN

2006 RES University of Alabama at Birmingham

2003 MD University of Alabama at Birmingham

2002 PhD University of Alabama at Birmingham

1988 MS Vanderbilt University

1986 BA Brown University
Research

Non-alcoholic fatty liver disease, insulin resistance, obesity, hepatic fibrosis, and apoptosis.
Publications

Function of inhibitor of Bruton's tyrosine kinase isoform a (IBTKa) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response.
Willy JA; Young SK; Mosley AL; Gawrieh S; Stevens JL; Masuoka HC; Wek RC; The Journal of biological chemistry 2017 Jul 14

Multifocal Gastric Ulcers Caused by Diffuse Large B Cell Lymphoma in a Patient With Significant Weight Loss.
Gromski MA; Peng JL; Zhou J; Masuoka HC; Suvannasankha A; Liangpunsakul S; Journal of investigative medicine high impact case reports 2016 Dec 1

Liver injury and fibrosis induced by dietary challenge in the Ossabaw miniature Swine.
Liang T; Alloosh M; Bell LN; Fullenkamp A; Saxena R; Van Alstine W; Bybee P; Werling K; Sturek M; Chalasani N; Masuoka HC; PloS one 2015 May 15

Individuals with Primary Sclerosing Cholangitis Have Elevated Levels of Biomarkers for Apoptosis but Not Necrosis.
Masuoka HC; Vuppalanchi R; Deppe R; Bybee P; Comerford M; Liangpunsakul S; Ghabril M; Chalasani N; Digestive diseases and sciences 2015 Jul 21

CHOP links endoplasmic reticulum stress to NF-?B activation in the pathogenesis of nonalcoholic steatohepatitis.
Willy JA; Young SK; Stevens JL; Masuoka HC; Wek RC; Molecular biology of the cell 2015 Apr 22

Relationship between changes in serum levels of keratin 18 and changes in liver histology in children and adults with nonalcoholic fatty liver disease.
Vuppalanchi R; Jain AK; Deppe R; Yates K; Comerford M; Masuoka HC; Neuschwander-Tetri BA; Loomba R; Brunt EM; Kleiner DE; Molleston JP; Schwimmer JB; Lavine JE; Tonascia J; Chalasani N; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2014 May 17

Nonalcoholic fatty liver disease: an emerging threat to obese and diabetic individuals.
Masuoka HC; Chalasani N; Annals of the New York Academy of Sciences 2013 Jan 30

Transplantation for cholangiocarcinoma.
Masuoka HC; Rosen CB; Clinics in liver disease 2011 Nov
Board Certifications

American Board of Internal Medicine - Gastroenterology

American Board of Internal Medicine - Internal Medicine
Clinical Interests

Non-alcoholic fatty liver disease, biliary tract diseases, cholangiocarcinoma, hepatocellular carcinoma, and liver transplantation.

Research Labs

Faculty research at IU School of Medicine is transforming health. Details about the medical research being conducted in faculty labs throughout IU School of Medicine are available in the Research section of this site.

Faculty Labs