Brian Walker, PhD
Daniel and Lori Efroymson Professor of Oncology
Professor of Medicine
Professor of Medical & Molecular Genetics
Adjunct Professor, BioHealth Informatics
- bw75@iu.edu
- Address
-
Joseph E. Walther Hall
980 W. Walnut St., C310
Indianapolis, IN 46202-0000 - PubMed:
| Year | Degree | Institution |
|---|---|---|
| 2000 | PhD | University of London |
| 1996 | BSC | University of Edinburgh |
Genomics and epigenetics of multiple myeloma (MM) and related plasma cell dyscrasias.
Alternative splicing in multiple myeloma is associated with the non-homologous end joining pathway.
Liu E; Becker N; Sudha P; Dong C; Liu Y; Keats J; Morgan G; Walker BA; Blood cancer journal 2023 Jan 20
Liu E; Becker N; Sudha P; Dong C; Liu Y; Keats J; Morgan G; Walker BA; Blood cancer journal 2023 Jan 20
Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma.
Ansari-Pour N; Samur M; Flynt E; Gooding S; Towfic F; Stong N; Estevez MO; Mavrommatis K; Walker B; Morgan G; Munshi N; Avet-Loiseau H; Thakurta A; Blood 2023 Feb 9
Ansari-Pour N; Samur M; Flynt E; Gooding S; Towfic F; Stong N; Estevez MO; Mavrommatis K; Walker B; Morgan G; Munshi N; Avet-Loiseau H; Thakurta A; Blood 2023 Feb 9
Structural variants shape the genomic landscape and clinical outcome of multiple myeloma.
Ashby C; Boyle EM; Bauer MA; Mikulasova A; Wardell CP; Williams L; Siegel A; Blaney P; Braunstein M; Kaminetsky D; Keats J; Maura F; Landgren O; Walker BA; Davies FE; Morgan GJ; Blood cancer journal 2022 May 30
Ashby C; Boyle EM; Bauer MA; Mikulasova A; Wardell CP; Williams L; Siegel A; Blaney P; Braunstein M; Kaminetsky D; Keats J; Maura F; Landgren O; Walker BA; Davies FE; Morgan GJ; Blood cancer journal 2022 May 30
Chromosomal abnormalities in multiple myeloma.
Mikulasova A; Morgan GJ; Walker BA; Nature reviews. Disease primers 2022 Jun 16
Mikulasova A; Morgan GJ; Walker BA; Nature reviews. Disease primers 2022 Jun 16
Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes.
Bustoros M; Anand S; Sklavenitis-Pistofidis R; Redd R; Boyle EM; Zhitomirsky B; Dunford AJ; Tai YT; Chavda SJ; Boehner C; Neuse CJ; Rahmat M; Dutta A; Casneuf T; Verona R; Kastritis E; Trippa L; Stewart C; Walker BA; Davies FE; Dimopoulos MA; Bergsagel PL; Yong K; Morgan GJ; Aguet F; Getz G; Ghobrial IM; Nature communications 2022 Jun 15
Bustoros M; Anand S; Sklavenitis-Pistofidis R; Redd R; Boyle EM; Zhitomirsky B; Dunford AJ; Tai YT; Chavda SJ; Boehner C; Neuse CJ; Rahmat M; Dutta A; Casneuf T; Verona R; Kastritis E; Trippa L; Stewart C; Walker BA; Davies FE; Dimopoulos MA; Bergsagel PL; Yong K; Morgan GJ; Aguet F; Getz G; Ghobrial IM; Nature communications 2022 Jun 15
Perspectives on the Risk-Stratified Treatment of Multiple Myeloma.
Davies FE; Pawlyn C; Usmani SZ; San-Miguel JF; Einsele H; Boyle EM; Corre J; Auclair D; Cho HJ; Lonial S; Sonneveld P; Stewart AK; Bergsagel PL; Kaiser MF; Weisel K; Keats JJ; Mikhael JR; Morgan KE; Ghobrial IM; Orlowski RZ; Landgren CO; Gay F; Caers J; Chng WJ; Chari A; Walker BA; Kumar SK; Costa LJ; Anderson KC; Morgan GJ; Blood cancer discovery 2022 Jul 6
Davies FE; Pawlyn C; Usmani SZ; San-Miguel JF; Einsele H; Boyle EM; Corre J; Auclair D; Cho HJ; Lonial S; Sonneveld P; Stewart AK; Bergsagel PL; Kaiser MF; Weisel K; Keats JJ; Mikhael JR; Morgan KE; Ghobrial IM; Orlowski RZ; Landgren CO; Gay F; Caers J; Chng WJ; Chari A; Walker BA; Kumar SK; Costa LJ; Anderson KC; Morgan GJ; Blood cancer discovery 2022 Jul 6
High-resolution simulations of chromatin folding at genomic rearrangements in malignant B cells provide mechanistic insights into proto-oncogene deregulation.
Rico D; Kent D; Karataraki N; Mikulasova A; Berlinguer-Palmini R; Walker BA; Javierre BM; Russell LJ; Brackley CA; Genome research 2022 Jul 21
Rico D; Kent D; Karataraki N; Mikulasova A; Berlinguer-Palmini R; Walker BA; Javierre BM; Russell LJ; Brackley CA; Genome research 2022 Jul 21
Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma.
Sudha P; Ahsan A; Ashby C; Kausar T; Khera A; Kazeroun MH; Hsu CC; Wang L; Fitzsimons E; Salminen O; Blaney P; Czader M; Williams J; Abu Zaid MI; Ansari-Pour N; Yong KL; van Rhee F; Pierceall WE; Morgan GJ; Flynt E; Gooding S; Abonour R; Ramasamy K; Thakurta A; Walker BA; Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Jul 1
Sudha P; Ahsan A; Ashby C; Kausar T; Khera A; Kazeroun MH; Hsu CC; Wang L; Fitzsimons E; Salminen O; Blaney P; Czader M; Williams J; Abu Zaid MI; Ansari-Pour N; Yong KL; van Rhee F; Pierceall WE; Morgan GJ; Flynt E; Gooding S; Abonour R; Ramasamy K; Thakurta A; Walker BA; Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Jul 1
Diagnostic Evidence GAuge of Single cells (DEGAS): a flexible deep transfer learning framework for prioritizing cells in relation to disease.
Johnson TS; Yu CY; Huang Z; Xu S; Wang T; Dong C; Shao W; Zaid MA; Huang X; Wang Y; Bartlett C; Zhang Y; Walker BA; Liu Y; Huang K; Zhang J; Genome medicine 2022 Feb 1
Johnson TS; Yu CY; Huang Z; Xu S; Wang T; Dong C; Shao W; Zaid MA; Huang X; Wang Y; Bartlett C; Zhang Y; Walker BA; Liu Y; Huang K; Zhang J; Genome medicine 2022 Feb 1
The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states.
Rasche L; Schinke C; Maura F; Bauer MA; Ashby C; Deshpande S; Poos AM; Zangari M; Thanendrarajan S; Davies FE; Walker BA; Barlogie B; Landgren O; Morgan GJ; van Rhee F; Weinhold N; Nature communications 2022 Aug 3
Rasche L; Schinke C; Maura F; Bauer MA; Ashby C; Deshpande S; Poos AM; Zangari M; Thanendrarajan S; Davies FE; Walker BA; Barlogie B; Landgren O; Morgan GJ; van Rhee F; Weinhold N; Nature communications 2022 Aug 3
Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement.
Bomken S; Enshaei A; Schwalbe EC; Mikulasova A; Dai Y; Zaka M; Fung KT; Bashton M; Lim H; Jones L; Karataraki N; Winterman E; Ashby C; Attarbaschi A; Bertrand Y; Bradtke J; Buldini B; Burke GA; Cazzaniga G; Gohring G; De Groot-Kruseman HA; Haferlach C; Nigro LL; Parihar M; Plesa A; Seaford E; Sonneveld E; Strehl S; Van der Velden VH; Rand V; Hunger SP; Harrison CJ; Bacon CM; Van Delft FW; Loh ML; Moppett J; Vormoor J; Walker BA; Moorman AV; Russell LJ; Haematologica 2022 Apr 28
Bomken S; Enshaei A; Schwalbe EC; Mikulasova A; Dai Y; Zaka M; Fung KT; Bashton M; Lim H; Jones L; Karataraki N; Winterman E; Ashby C; Attarbaschi A; Bertrand Y; Bradtke J; Buldini B; Burke GA; Cazzaniga G; Gohring G; De Groot-Kruseman HA; Haferlach C; Nigro LL; Parihar M; Plesa A; Seaford E; Sonneveld E; Strehl S; Van der Velden VH; Rand V; Hunger SP; Harrison CJ; Bacon CM; Van Delft FW; Loh ML; Moppett J; Vormoor J; Walker BA; Moorman AV; Russell LJ; Haematologica 2022 Apr 28
Intron retention-induced neoantigen load correlates with unfavorable prognosis in multiple myeloma.
Dong C; Cesarano A; Bombaci G; Reiter JL; Yu CY; Wang Y; Jiang Z; Zaid MA; Huang K; Lu X; Walker BA; Perna F; Liu Y; Oncogene 2021 Sep 9
Dong C; Cesarano A; Bombaci G; Reiter JL; Yu CY; Wang Y; Jiang Z; Zaid MA; Huang K; Lu X; Walker BA; Perna F; Liu Y; Oncogene 2021 Sep 9
Chromosomal 1q21 abnormalities in multiple myeloma: a review of translational, clinical research, and therapeutic strategies.
Bisht K; Walker B; Kumar SK; Spicka I; Moreau P; Martin T; Costa LJ; Richter J; Fukao T; Macé S; van de Velde H; Expert review of hematology 2021 Oct 8
Bisht K; Walker B; Kumar SK; Spicka I; Moreau P; Martin T; Costa LJ; Richter J; Fukao T; Macé S; van de Velde H; Expert review of hematology 2021 Oct 8
Impact of Etiological Cytogenetic Abnormalities on the Depth of Immunoparesis and Survival in Newly Diagnosed Multiple Myeloma.
Caro J; Cairns D; Menzies T; Boyle E; Pawlyn C; Cook G; Kaiser M; Walker BA; Owen R; Jackson GH; Morgan GJ; Heaney J; Drayson MT; Davies FE; Clinical lymphoma, myeloma & leukemia 2021 Oct 18
Caro J; Cairns D; Menzies T; Boyle E; Pawlyn C; Cook G; Kaiser M; Walker BA; Owen R; Jackson GH; Morgan GJ; Heaney J; Drayson MT; Davies FE; Clinical lymphoma, myeloma & leukemia 2021 Oct 18
Chromothripsis as a pathogenic driver of multiple myeloma.
Maura F; Boyle EM; Rustad EH; Ashby C; Kaminetzky D; Bruno B; Braunstein M; Bauer M; Blaney P; Wang Y; Ghamlouch H; Williams L; Stoeckle J; Davies FE; Walker BA; Maclachlan K; Diamond B; Landgren O; Morgan GJ; Seminars in cell & developmental biology 2021 May 3
Maura F; Boyle EM; Rustad EH; Ashby C; Kaminetzky D; Bruno B; Braunstein M; Bauer M; Blaney P; Wang Y; Ghamlouch H; Williams L; Stoeckle J; Davies FE; Walker BA; Maclachlan K; Diamond B; Landgren O; Morgan GJ; Seminars in cell & developmental biology 2021 May 3
Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities.
Oben B; Froyen G; Maclachlan KH; Leongamornlert D; Abascal F; Zheng-Lin B; Yellapantula V; Derkach A; Geerdens E; Diamond BT; Arijs I; Maes B; Vanhees K; Hultcrantz M; Manasanch EE; Kazandjian D; Lesokhin A; Dogan A; Zhang Y; Mikulasova A; Walker B; Morgan G; Campbell PJ; Landgren O; Rummens JL; Bolli N; Maura F; Nature communications 2021 Mar 25
Oben B; Froyen G; Maclachlan KH; Leongamornlert D; Abascal F; Zheng-Lin B; Yellapantula V; Derkach A; Geerdens E; Diamond BT; Arijs I; Maes B; Vanhees K; Hultcrantz M; Manasanch EE; Kazandjian D; Lesokhin A; Dogan A; Zhang Y; Mikulasova A; Walker B; Morgan G; Campbell PJ; Landgren O; Rummens JL; Bolli N; Maura F; Nature communications 2021 Mar 25
Improving prognostic assignment in older adults with multiple myeloma using acquired genetic features, clonal hemopoiesis and telomere length.
Boyle EM; Williams L; Blaney P; Ashby C; Bauer M; Walker BA; Ghamlouch H; Choi J; Perrial E; Wang Y; Caro J; Stoeckle JH; Arbini A; Kaminetzky D; Braunstein M; Bruno B; Razzo B; Diamond B; Maclachlan K; Maura F; Landgren O; Litke R; Fegan CD; Keats J; Auclair D; Davies FE; Morgan GJ; Leukemia 2021 Jun 19
Boyle EM; Williams L; Blaney P; Ashby C; Bauer M; Walker BA; Ghamlouch H; Choi J; Perrial E; Wang Y; Caro J; Stoeckle JH; Arbini A; Kaminetzky D; Braunstein M; Bruno B; Razzo B; Diamond B; Maclachlan K; Maura F; Landgren O; Litke R; Fegan CD; Keats J; Auclair D; Davies FE; Morgan GJ; Leukemia 2021 Jun 19
High-risk transcriptional profiles in multiple myeloma are an acquired feature that can occur in any subtype and more frequently with each subsequent relapse.
Boyle EM; Rosenthal A; Wang Y; Farmer P; Rutherford M; Ashby C; Bauer M; Johnson SK; Wardell CP; Hoering A; Schinke C; Thanendrarajan S; Zangari M; Barlogie B; Davies FE; Walker BA; van Rhee F; Morgan GJ; British journal of haematology 2021 Jul 9
Boyle EM; Rosenthal A; Wang Y; Farmer P; Rutherford M; Ashby C; Bauer M; Johnson SK; Wardell CP; Hoering A; Schinke C; Thanendrarajan S; Zangari M; Barlogie B; Davies FE; Walker BA; van Rhee F; Morgan GJ; British journal of haematology 2021 Jul 9
The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Boyle EM; Deshpande S; Tytarenko R; Ashby C; Wang Y; Bauer MA; Johnson SK; Wardell CP; Thanendrarajan S; Zangari M; Facon T; Dumontet C; Barlogie B; Arbini A; Rustad EH; Maura F; Landgren O; Zhan F; van Rhee F; Schinke C; Davies FE; Morgan GJ; Walker BA; Nature communications 2021 Jan 12
Boyle EM; Deshpande S; Tytarenko R; Ashby C; Wang Y; Bauer MA; Johnson SK; Wardell CP; Thanendrarajan S; Zangari M; Facon T; Dumontet C; Barlogie B; Arbini A; Rustad EH; Maura F; Landgren O; Zhan F; van Rhee F; Schinke C; Davies FE; Morgan GJ; Walker BA; Nature communications 2021 Jan 12
Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers.
Mikulasova A; Kent D; Trevisan-Herraz M; Karataraki N; Fung KTM; Ashby C; Cieslak A; Yaccoby S; van Rhee F; Zangari M; Thanendrarajan S; Schinke C; Morgan GJ; Asnafi V; Spicuglia S; Brackley CA; Corcoran AE; Hambleton S; Walker BA; Rico D; Russell LJ; Genome research 2021 Dec 21
Mikulasova A; Kent D; Trevisan-Herraz M; Karataraki N; Fung KTM; Ashby C; Cieslak A; Yaccoby S; van Rhee F; Zangari M; Thanendrarajan S; Schinke C; Morgan GJ; Asnafi V; Spicuglia S; Brackley CA; Corcoran AE; Hambleton S; Walker BA; Rico D; Russell LJ; Genome research 2021 Dec 21
Insights into high-risk multiple myeloma from an analysis of the role of PHF19 in cancer.
Ghamlouch H; Boyle EM; Blaney P; Wang Y; Choi J; Williams L; Bauer M; Auclair D; Bruno B; Walker BA; Davies FE; Morgan GJ; Journal of experimental & clinical cancer research : CR 2021 Dec 2
Ghamlouch H; Boyle EM; Blaney P; Wang Y; Choi J; Williams L; Bauer M; Auclair D; Bruno B; Walker BA; Davies FE; Morgan GJ; Journal of experimental & clinical cancer research : CR 2021 Dec 2
Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs.
Jones JR; Barber A; Le Bihan YV; Weinhold N; Ashby C; Walker BA; Wardell CP; Wang H; Kaiser MF; Jackson GH; Davies FE; Chopra R; Morgan GJ; Pawlyn C; Leukemia 2021 Aug 9
Jones JR; Barber A; Le Bihan YV; Weinhold N; Ashby C; Walker BA; Wardell CP; Wang H; Kaiser MF; Jackson GH; Davies FE; Chopra R; Morgan GJ; Pawlyn C; Leukemia 2021 Aug 9
Plasma cells expression from smouldering myeloma to myeloma reveals the importance of the PRC2 complex, cell cycle progression, and the divergent evolutionary pathways within the different molecular subgroups.
Boyle EM; Rosenthal A; Ghamlouch H; Wang Y; Farmer P; Rutherford M; Ashby C; Bauer M; Johnson SK; Wardell CP; Wang Y; Hoering A; Schinke C; Thanendrarajan S; Zangari M; Barlogie B; Dhodapkar MV; Davies FE; Morgan GJ; van Rhee F; Walker BA; Leukemia 2021 Aug 7
Boyle EM; Rosenthal A; Ghamlouch H; Wang Y; Farmer P; Rutherford M; Ashby C; Bauer M; Johnson SK; Wardell CP; Wang Y; Hoering A; Schinke C; Thanendrarajan S; Zangari M; Barlogie B; Dhodapkar MV; Davies FE; Morgan GJ; van Rhee F; Walker BA; Leukemia 2021 Aug 7
PHF19 inhibition as a therapeutic target in multiple myeloma.
Schinke CD; Bird JT; Qu P; Yaccoby S; Lyzogubov VV; Shelton R; Ling W; Boyle EM; Deshpande S; Byrum SD; Washam C; Mackintosh S; Stephens O; Thanendrarajan S; Zangari M; Shaughnessy J Jr; Zhan F; Barlogie B; van Rhee F; Walker BA; Current research in translational medicine 2021 Apr 22
Schinke CD; Bird JT; Qu P; Yaccoby S; Lyzogubov VV; Shelton R; Ling W; Boyle EM; Deshpande S; Byrum SD; Washam C; Mackintosh S; Stephens O; Thanendrarajan S; Zangari M; Shaughnessy J Jr; Zhan F; Barlogie B; van Rhee F; Walker BA; Current research in translational medicine 2021 Apr 22
Cryopreservation Preserves Cell-Type Composition and Gene Expression Profiles in Bone Marrow Aspirates From Multiple Myeloma Patients.
Chen D; Abu Zaid MI; Reiter JL; Czader M; Wang L; McGuire P; Xuei X; Gao H; Huang K; Abonour R; Walker BA; Liu Y; Frontiers in genetics 2021 Apr 21
Chen D; Abu Zaid MI; Reiter JL; Czader M; Wang L; McGuire P; Xuei X; Gao H; Huang K; Abonour R; Walker BA; Liu Y; Frontiers in genetics 2021 Apr 21
Monitoring treatment response and disease progression in myeloma with circulating cell-free DNA.
Deshpande S; Tytarenko RG; Wang Y; Boyle EM; Ashby C; Schinke CD; Thanendrarajan S; Zangari M; Zhan F; Davies FE; Morgan GJ; van Rhee F; Walker BA; European journal of haematology 2020 Oct 26
Deshpande S; Tytarenko RG; Wang Y; Boyle EM; Ashby C; Schinke CD; Thanendrarajan S; Zangari M; Zhan F; Davies FE; Morgan GJ; van Rhee F; Walker BA; European journal of haematology 2020 Oct 26
Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials.
Danziger SA; McConnell M; Gockley J; Young MH; Rosenthal A; Schmitz F; Reiss DJ; Farmer P; Alapat DV; Singh A; Ashby C; Bauer M; Ren Y; Smith K; Couto SS; van Rhee F; Davies F; Zangari M; Petty N; Orlowski RZ; Dhodapkar MV; Copeland WB; Fox B; Hoering A; Fitch A; Newhall K; Barlogie B; Trotter MWB; Hershberg RM; Walker BA; Dervan AP; Ratushny AV; Morgan GJ; PLoS medicine 2020 Nov 4
Danziger SA; McConnell M; Gockley J; Young MH; Rosenthal A; Schmitz F; Reiss DJ; Farmer P; Alapat DV; Singh A; Ashby C; Bauer M; Ren Y; Smith K; Couto SS; van Rhee F; Davies F; Zangari M; Petty N; Orlowski RZ; Dhodapkar MV; Copeland WB; Fox B; Hoering A; Fitch A; Newhall K; Barlogie B; Trotter MWB; Hershberg RM; Walker BA; Dervan AP; Ratushny AV; Morgan GJ; PLoS medicine 2020 Nov 4
Two Cases of Vancomycin-Resistant <i>Enterococcus faecium</i> Bacteremia With Development of Daptomycin-Resistant Phenotype and its Detection Using Oxford Nanopore Sequencing.
Udaondo Z; Jenjaroenpun P; Wongsurawat T; Meyers E; Anderson C; Lopez J; Mohan M; Tytarenko R; Walker B; Ussery D; Kothari A; Jun SR; Open forum infectious diseases 2020 May 23
Udaondo Z; Jenjaroenpun P; Wongsurawat T; Meyers E; Anderson C; Lopez J; Mohan M; Tytarenko R; Walker B; Ussery D; Kothari A; Jun SR; Open forum infectious diseases 2020 May 23
Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns.
Schinke C; Boyle EM; Ashby C; Wang Y; Lyzogubov V; Wardell C; Qu P; Hoering A; Deshpande S; Ryan K; Thanendrarajan S; Mohan M; Yarlagadda N; Khan M; Choudhury SR; Zangari M; van Rhee F; Davies F; Barlogie B; Morgan G; Walker BA; Blood cancer journal 2020 Jun 19
Schinke C; Boyle EM; Ashby C; Wang Y; Lyzogubov V; Wardell C; Qu P; Hoering A; Deshpande S; Ryan K; Thanendrarajan S; Mohan M; Yarlagadda N; Khan M; Choudhury SR; Zangari M; van Rhee F; Davies F; Barlogie B; Morgan G; Walker BA; Blood cancer journal 2020 Jun 19
Long-term outcomes after autologous stem cell transplantation for multiple myeloma.
Nishimura KK; Barlogie B; van Rhee F; Zangari M; Walker BA; Rosenthal A; Schinke C; Thanendrarajan S; Davies FE; Hoering A; Morgan GJ; Blood advances 2020 Jan 28
Nishimura KK; Barlogie B; van Rhee F; Zangari M; Walker BA; Rosenthal A; Schinke C; Thanendrarajan S; Davies FE; Hoering A; Morgan GJ; Blood advances 2020 Jan 28
<i>BRAF</i> and <i>DIS3</i> Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma.
Boyle EM; Ashby C; Tytarenko RG; Deshpande S; Wang H; Wang Y; Rosenthal A; Sawyer J; Tian E; Flynt E; Hoering A; Johnson SK; Rutherford MW; Wardell CP; Bauer MA; Dumontet C; Facon T; Thanendrarajan S; Schinke CD; Zangari M; van Rhee F; Barlogie B; Cairns D; Jackson G; Thakurta A; Davies FE; Morgan GJ; Walker BA; Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Jan 27
Boyle EM; Ashby C; Tytarenko RG; Deshpande S; Wang H; Wang Y; Rosenthal A; Sawyer J; Tian E; Flynt E; Hoering A; Johnson SK; Rutherford MW; Wardell CP; Bauer MA; Dumontet C; Facon T; Thanendrarajan S; Schinke CD; Zangari M; van Rhee F; Barlogie B; Cairns D; Jackson G; Thakurta A; Davies FE; Morgan GJ; Walker BA; Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Jan 27
Differential RNA splicing as a potentially important driver mechanism in multiple myeloma.
Bauer MA; Ashby C; Wardell C; Boyle EM; Ortiz M; Flynt E; Thakurta A; Morgan G; Walker BA; Haematologica 2020 Feb 20
Bauer MA; Ashby C; Wardell C; Boyle EM; Ortiz M; Flynt E; Thakurta A; Morgan G; Walker BA; Haematologica 2020 Feb 20
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease.
Mason MJ; Schinke C; Eng CLP; Towfic F; Gruber F; Dervan A; White BS; Pratapa A; Guan Y; Chen H; Cui Y; Li B; Yu T; Chaibub Neto E; Mavrommatis K; Ortiz M; Lyzogubov V; Bisht K; Dai HY; Schmitz F; Flynt E; Dan Rozelle; Danziger SA; Ratushny A; Multiple Myeloma DREAM Consortium.; Dalton WS; Goldschmidt H; Avet-Loiseau H; Samur M; Hayete B; Sonneveld P; Shain KH; Munshi N; Auclair D; Hose D; Morgan G; Trotter M; Bassett D; Goke J; Walker BA; Thakurta A; Guinney J; Leukemia 2020 Feb 14
Mason MJ; Schinke C; Eng CLP; Towfic F; Gruber F; Dervan A; White BS; Pratapa A; Guan Y; Chen H; Cui Y; Li B; Yu T; Chaibub Neto E; Mavrommatis K; Ortiz M; Lyzogubov V; Bisht K; Dai HY; Schmitz F; Flynt E; Dan Rozelle; Danziger SA; Ratushny A; Multiple Myeloma DREAM Consortium.; Dalton WS; Goldschmidt H; Avet-Loiseau H; Samur M; Hayete B; Sonneveld P; Shain KH; Munshi N; Auclair D; Hose D; Morgan G; Trotter M; Bassett D; Goke J; Walker BA; Thakurta A; Guinney J; Leukemia 2020 Feb 14
The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma.
Choudhury SR; Ashby C; Tytarenko R; Bauer M; Wang Y; Deshpande S; Den J; Schinke C; Zangari M; Thanendrarajan S; Davies FE; van Rhee F; Morgan GJ; Walker BA; Journal of hematology & oncology 2020 Aug 6
Choudhury SR; Ashby C; Tytarenko R; Bauer M; Wang Y; Deshpande S; Den J; Schinke C; Zangari M; Thanendrarajan S; Davies FE; van Rhee F; Morgan GJ; Walker BA; Journal of hematology & oncology 2020 Aug 6
TarPan: an easily adaptable targeted sequencing panel viewer for research and clinical use.
Ashby C; Rutherford M; Bauer MA; Peterson EA; Wang Y; Boyle EM; Wardell CP; Walker BA; BMC bioinformatics 2020 Apr 15
Ashby C; Rutherford M; Bauer MA; Peterson EA; Wang Y; Boyle EM; Wardell CP; Walker BA; BMC bioinformatics 2020 Apr 15
A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations.
George SL; Izquierdo E; Campbell J; Koutroumanidou E; Proszek P; Jamal S; Hughes D; Yuan L; Marshall LV; Carceller F; Chisholm JC; Vaidya S; Mandeville H; Angelini P; Wasti A; Bexelius T; Thway K; Gatz SA; Clarke M; Al-Lazikani B; Barone G; Anderson J; Tweddle DA; Gonzalez D; Walker BA; Barton J; Depani S; Eze J; Ahmed SW; Moreno L; Pearson A; Shipley J; Jones C; Hargrave D; Jacques TS; Hubank M; Chesler L; European journal of cancer (Oxford, England : 1990) 2019 Sep 19
George SL; Izquierdo E; Campbell J; Koutroumanidou E; Proszek P; Jamal S; Hughes D; Yuan L; Marshall LV; Carceller F; Chisholm JC; Vaidya S; Mandeville H; Angelini P; Wasti A; Bexelius T; Thway K; Gatz SA; Clarke M; Al-Lazikani B; Barone G; Anderson J; Tweddle DA; Gonzalez D; Walker BA; Barton J; Depani S; Eze J; Ahmed SW; Moreno L; Pearson A; Shipley J; Jones C; Hargrave D; Jacques TS; Hubank M; Chesler L; European journal of cancer (Oxford, England : 1990) 2019 Sep 19
Inactivating <i>NF1</i> Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance.
Pearson A; Proszek P; Pascual J; Fribbens C; Shamsher MK; Kingston B; O'Leary B; Herrera-Abreu MT; Cutts RJ; Garcia-Murillas I; Bye H; Walker BA; Gonzalez De Castro D; Yuan L; Jamal S; Hubank M; Lopez-Knowles E; Schuster EF; Dowsett M; Osin P; Nerurkar A; Parton M; Okines AFC; Johnston SRD; Ring A; Turner NC; Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Oct 7
Pearson A; Proszek P; Pascual J; Fribbens C; Shamsher MK; Kingston B; O'Leary B; Herrera-Abreu MT; Cutts RJ; Garcia-Murillas I; Bye H; Walker BA; Gonzalez De Castro D; Yuan L; Jamal S; Hubank M; Lopez-Knowles E; Schuster EF; Dowsett M; Osin P; Nerurkar A; Parton M; Okines AFC; Johnston SRD; Ring A; Turner NC; Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Oct 7
Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma.
Mikulasova A; Ashby C; Tytarenko RG; Qu P; Rosenthal A; Dent JA; Ryan KR; Bauer MA; Wardell CP; Hoering A; Mavrommatis K; Trotter M; Deshpande S; Yaccoby S; Tian E; Keats J; Auclair D; Jackson GH; Davies FE; Thakurta A; Morgan GJ; Walker BA; Haematologica 2019 Jun 20
Mikulasova A; Ashby C; Tytarenko RG; Qu P; Rosenthal A; Dent JA; Ryan KR; Bauer MA; Wardell CP; Hoering A; Mavrommatis K; Trotter M; Deshpande S; Yaccoby S; Tian E; Keats J; Auclair D; Jackson GH; Davies FE; Thakurta A; Morgan GJ; Walker BA; Haematologica 2019 Jun 20
Daratumumab and dexamethasone is safe and effective for triple refractory myeloma patients: final results of the IFM 2014-04 (Etoile du Nord) trial.
Boyle EM; Leleu X; Petillon MO; Karlin L; Doyen C; Demarquette H; Royer B; Macro M; Moreau P; Fostier K; Marie-Lorraine C; Zarnitsky C; Perrot A; Herbaux C; Poulain S; Manier S; Beauvais D; Walker BA; Wardell CP; Vincent L; Frenzel L; Caillon H; Susanna S; Dejoie T; Avet-Loiseau H; Mohty M; Facon T; IFM2014-04 investigators.; British journal of haematology 2019 Jun 19
Boyle EM; Leleu X; Petillon MO; Karlin L; Doyen C; Demarquette H; Royer B; Macro M; Moreau P; Fostier K; Marie-Lorraine C; Zarnitsky C; Perrot A; Herbaux C; Poulain S; Manier S; Beauvais D; Walker BA; Wardell CP; Vincent L; Frenzel L; Caillon H; Susanna S; Dejoie T; Avet-Loiseau H; Mohty M; Facon T; IFM2014-04 investigators.; British journal of haematology 2019 Jun 19
Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of <i>TP53</i>.
Ashby C; Tytarenko RG; Wang Y; Weinhold N; Johnson SK; Bauer M; Wardell CP; Schinke C; Thanendrarajan S; Zangari M; van Rhee F; Davies FE; Sawyer JR; Morgan GJ; Walker BA; Oncotarget 2019 Jan 22
Ashby C; Tytarenko RG; Wang Y; Weinhold N; Johnson SK; Bauer M; Wardell CP; Schinke C; Thanendrarajan S; Zangari M; van Rhee F; Davies FE; Sawyer JR; Morgan GJ; Walker BA; Oncotarget 2019 Jan 22
Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients.
Jones JR; Weinhold N; Ashby C; Walker BA; Wardell C; Pawlyn C; Rasche L; Melchor L; Cairns DA; Gregory WM; Johnson D; Begum DB; Ellis S; Sherborne AL; Cook G; Kaiser MF; Drayson MT; Owen RG; Jackson GH; Davies FE; Greaves M; Morgan GJ; NCRI Haemato-Oncology CSG.; Haematologica 2019 Feb 7
Jones JR; Weinhold N; Ashby C; Walker BA; Wardell C; Pawlyn C; Rasche L; Melchor L; Cairns DA; Gregory WM; Johnson D; Begum DB; Ellis S; Sherborne AL; Cook G; Kaiser MF; Drayson MT; Owen RG; Jackson GH; Davies FE; Greaves M; Morgan GJ; NCRI Haemato-Oncology CSG.; Haematologica 2019 Feb 7
An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome.
Sawyer JR; Tian E; Walker BA; Wardell C; Lukacs JL; Sammartino G; Bailey C; Schinke CD; Thanendrarajan S; Davies FE; Morgan GJ; Barlogie B; Zangari M; van Rhee F; Blood cancer journal 2019 Aug 9
Sawyer JR; Tian E; Walker BA; Wardell C; Lukacs JL; Sammartino G; Bailey C; Schinke CD; Thanendrarajan S; Davies FE; Morgan GJ; Barlogie B; Zangari M; van Rhee F; Blood cancer journal 2019 Aug 9
Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes.
Went M; Kinnersley B; Sud A; Johnson DC; Weinhold N; Försti A; van Duin M; Orlando G; Mitchell JS; Kuiper R; Walker BA; Gregory WM; Hoffmann P; Jackson GH; Nöthen MM; da Silva Filho MI; Thomsen H; Broyl A; Davies FE; Thorsteinsdottir U; Hansson M; Kaiser M; Sonneveld P; Goldschmidt H; Stefansson K; Hemminki K; Nilsson B; Morgan GJ; Houlston RS; Human genomics 2019 Aug 20
Went M; Kinnersley B; Sud A; Johnson DC; Weinhold N; Försti A; van Duin M; Orlando G; Mitchell JS; Kuiper R; Walker BA; Gregory WM; Hoffmann P; Jackson GH; Nöthen MM; da Silva Filho MI; Thomsen H; Broyl A; Davies FE; Thorsteinsdottir U; Hansson M; Kaiser M; Sonneveld P; Goldschmidt H; Stefansson K; Hemminki K; Nilsson B; Morgan GJ; Houlston RS; Human genomics 2019 Aug 20
Draft Genome Sequences of 48 Vancomycin-Resistant Enterococcus faecium Strains Isolated from Inpatients with Bacteremia and Urinary Tract Infection.
Udaondo Z; Wongsurawat T; Jenjaroenpun P; Anderson C; Lopez J; Mohan M; Tytarenko R; Walker B; Nookaew I; Ussery D; Kothari A; Jun SR; Microbiology resource announcements 2019 Apr 11
Udaondo Z; Wongsurawat T; Jenjaroenpun P; Anderson C; Lopez J; Mohan M; Tytarenko R; Walker B; Nookaew I; Ussery D; Kothari A; Jun SR; Microbiology resource announcements 2019 Apr 11
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis.
Walker BA; Mavrommatis K; Wardell CP; Ashby TC; Bauer M; Davies F; Rosenthal A; Wang H; Qu P; Hoering A; Samur M; Towfic F; Ortiz M; Flynt E; Yu Z; Yang Z; Rozelle D; Obenauer J; Trotter M; Auclair D; Keats J; Bolli N; Fulciniti M; Szalat R; Moreau P; Durie B; Stewart AK; Goldschmidt H; Raab MS; Einsele H; Sonneveld P; San Miguel J; Lonial S; Jackson GH; Anderson KC; Avet-Loiseau H; Munshi N; Thakurta A; Morgan G; Leukemia 2018 Jul 2
Walker BA; Mavrommatis K; Wardell CP; Ashby TC; Bauer M; Davies F; Rosenthal A; Wang H; Qu P; Hoering A; Samur M; Towfic F; Ortiz M; Flynt E; Yu Z; Yang Z; Rozelle D; Obenauer J; Trotter M; Auclair D; Keats J; Bolli N; Fulciniti M; Szalat R; Moreau P; Durie B; Stewart AK; Goldschmidt H; Raab MS; Einsele H; Sonneveld P; San Miguel J; Lonial S; Jackson GH; Anderson KC; Avet-Loiseau H; Munshi N; Thakurta A; Morgan G; Leukemia 2018 Jul 2
Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma.
Rasche L; Alapat D; Kumar M; Gershner G; McDonald J; Wardell CP; Samant R; Van Hemert R; Epstein J; Williams AF; Thanendrarajan S; Schinke C; Bauer M; Ashby C; Tytarenko RG; van Rhee F; Walker BA; Zangari M; Barlogie B; Davies FE; Morgan GJ; Weinhold N; Leukemia 2018 Dec 20
Rasche L; Alapat D; Kumar M; Gershner G; McDonald J; Wardell CP; Samant R; Van Hemert R; Epstein J; Williams AF; Thanendrarajan S; Schinke C; Bauer M; Ashby C; Tytarenko RG; van Rhee F; Walker BA; Zangari M; Barlogie B; Davies FE; Morgan GJ; Weinhold N; Leukemia 2018 Dec 20
Royal College of Pathologists, UK
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